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The new edition of Mathematical Modeling, the survey text of choice for mathematical modeling courses, adds ample instructor support and online delivery for solutions manuals and software ancillaries.

From genetic engineering to hurricane prediction, mathematical models guide much of the decision making in our society. If the assumptions and methods underlying the modeling are flawed, the outcome can be disastrously poor. With mathematical modeling growing rapidly in so many scientific and technical disciplines, Mathematical Modeling, Fourth Edition provides a rigorous treatment of the subject. The book explores a range of approaches including optimization models, dynamic models and probability models.
Offers increased support for instructors, including MATLAB material as well as other on-line resources Features new sections on time series analysis and diffusion models Provides additional problems with international focus such as whale and dolphin populations, plus updated optimization problems

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Principles of Environmental Physics: Plants, Animals, and the Atmosphere, 4e, provides a basis for understanding the complex physical interactions of plants and animals with their natural environment. It is the essential reference to provide environmental and ecological scientists and researchers with the physical principles, analytic tools, and data analysis methods they need to solve problems. This book describes the principles by which radiative energy reaches the earths surface and reviews the latest knowledge concerning the surface radiation budget. The processes of radiation, convection, conduction, evaporation, and carbon dioxide exchange are analyzed. Many applications of environmental physics principles are reviewed, including the roles of surface albedo and atmospheric aerosols in modifying microclimate and climate, remote sensing of vegetation properties, wind forces on trees and crops, dispersion of pathogens and aerosols, controls of evaporation from vegetation and soil (including implications of changing weather and climate), and interpretation of micrometeorological measurements of carbon dioxide and other trace gas fluxes.
Presents a unique synthesis of micrometeorology and ecology in its widest sense Deals quantitatively with the impact of weather on living systems but also with the interactions between organisms and the atmosphere that are a central feature of life on earth Offers numerous worked examples and problems with solutions Provides many examples of laboratory and field measurements and their interpretation Includes an up-to-date bibliography and review of recent micrometeorological applications in forestry, ecology, hydrology, and agriculture

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Strategy and Statistics in Clinical Trials

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A Non-Statisticians Guide to Thinking, Designing and Executing

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Strategy and Statistics in Clinical Trials deals with the research processes and the role of statistics in these processes. The book offers real-life case studies and provides a practical, how to guide to biomedical R&D.; It describes the statistical building blocks and concepts of clinical trials and promotes effective cooperation between statisticians and important other parties.

The discussion is organized around 15 chapters. After providing an overview of clinical development and statistics, the book explores questions when planning clinical trials, along with the attributes of medical products. It then explains how to set research objectives and goes on to consider statistical thinking, estimation, testing procedures, and statistical significance, explanation and prediction. The rest of the book focuses on exploratory and confirmatory clinical trials; hypothesis testing and multiplicity; elements of clinical trial design; choosing trial endpoints; and determination of sample size.

This book is for all individuals engaged in clinical research who are interested in a better understanding of statistics, including professional clinical researchers, professors, physicians, and researchers in laboratory. It will also be of interest to corporate and government laboratories, clinical research nurses, members of the allied health professions, and post-doctoral and graduate students.
Enables non-statisticians to better understand research processes and statistics' role in these processes Offers real-life case studies and provides a practical, "how to" guide to biomedical R&D; Delineates the statistical building blocks and concepts of clinical trials Promotes effective cooperation between statisticians and important other parties

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Numerical Methods using MATLAB, 3e, is an extensive reference offering hundreds of useful and important numerical algorithms that can be implemented into MATLAB for a graphical interpretation to help researchers analyze a particular outcome. Many worked examples are given together with exercises and solutions to illustrate how numerical methods can be used to study problems that have applications in the biosciences, chaos, optimization, engineering and science across the board.
Over 500 numerical algorithms, their fundamental principles, and applications Graphs are used extensively to clarify the complexity of problems Includes coded genetic algorithms Includes the Lagrange multiplier method User-friendly and written in a conversational style

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Computer and Machine Vision: Theory, Algorithms, Practicalities (previously entitled Machine Vision) clearly and systematically presents the basic methodology of computer and machine vision, covering the essential elements of the theory while emphasizing algorithmic and practical design constraints. This fully revised fourth edition has brought in more of the concepts and applications of computer vision, making it a very comprehensive and up-to-date tutorial text suitable for graduate students, researchers and R&D; engineers working in this vibrant subject.

Key features include:

Practical examples and case studies give the ins and outs of developing real-world vision systems, giving engineers the realities of implementing the principles in practice New chapters containing case studies on surveillance and driver assistance systems give practical methods on these cutting-edge applications in computer vision Necessary mathematics and essential theory are made approachable by careful explanations and well-illustrated examples Updated content and new sections cover topics such as human iris location, image stitching, line detection using RANSAC, performance measures, and hyperspectral imaging The recent developments section now included in each chapter will be useful in bringing students and practitioners up to date with the subject Mathematics and essential theory are made approachable by careful explanations and well-illustrated examples Updated content and new sections cover topics such as human iris location, image stitching, line detection using RANSAC, performance measures, and hyperspectral imaging The recent developments section now included in each chapter will be useful in bringing students and practitioners up to date with the subject

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Adverse Effects of Engineered Nanomaterials

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Exposure, Toxicology, and Impact on Human Health

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Adverse Effects of Engineered Nanoparticles: A Disease-Oriented Approach provides a systematic evaluation of representative engineered nanomaterial (ENM) of high volume production and of high economic importance. Each class of nanomaterials discussed includes information on what scientists, industry, regulatory agencies and the general public need to know about nanosafety. This book, written by leading international experts in nanotoxicology and nanmoedicine, gives a comprehensive view of the health impact of ENM, focusing on their potential adverse effects in exposed workers, consumers and patients. The beneficial applications, both diagnostic and therapeutic, of ENM are also highlighted. This book fills an important need in terms of bridging the gap between experimental findings and human exposure to ENM, and the clinical and pathological consequences of such exposure in the human population.
Multi-authored book written by leading US and European experts on nanotoxicology and nanomedicine Discusses the health implications and a clinical translation of experimental data in this area Takes a schematic, non-exhaustive approach to summarize the most important research data in this field Includes a glossary, with a brief explanation of the term and with a reference to where the term or phrase has been used will be included within the book

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Bengt Fadeel, Antonio Pietroiusti, Anna A. Shvedova

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Handbook of Natural Gas Transmission and Processing

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A unique, well-documented, and forward-thinking work, the second edition of Handbook of Natural Gas Transmission and Processing continues to present a thoroughly updated, authoritative, and comprehensive description of all major aspects of natural gas transmission and processing. It provides an ideal platform for engineers, technologists, and operations personnel working in the natural gas industry to get a better understanding of any special requirements for optimal design and operations of natural gas transmission pipelines and processing plants. First book of its kind that covers all aspects of natural gas transmission and processing Provides pivotal updates on the latest technologies, which have not been addressed in-depth in any existing books Offers practical advice for design and operation based on sound engineering principles and established techniques Examines ways to select the best processing route for optimal design of gas-processing plants Contains new discussions on process modeling, control, and optimization in gas processing industry

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Polymer Electrolyte Fuel Cell Degradation

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For full market implementation of PEM fuel cells to become a reality, two main limiting technical issues must be overcome-cost and durability. This cutting-edge volume directly addresses the state-of-the-art advances in durability within every fuel cell stack component. Designed to be relevant to the professional community in addition to researchers, this book will serve as a valuable reference featuring topics covered nowhere else and a one-stop-shop to create a solid platform for understanding this important area of development. The reference covers aspects of durability in the entire fuel cell stack. Each chapter also includes vision of pathways forward and an explanation of the tools needed to continue along the path toward commercialization. Features expert insights from contributing authors who are key industrial and academic leaders in the field Includes coverage of two key topics in the field- Testing and Protocol for Durability, and Computational Modeling Aspects of PEFC Durability- which are newly emerging, pivotally important subjects not systematically covered anywhere else Undertakes aspects of durability across the entire fuel stack, from membranes to bipolar plates

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Matthew M. Mench, Emin Caglan Kumbur, T. Nejat Veziroglu

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Structural Analysis of Complex Materials

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Underneath the Bragg Peaks: Structural Analysis of Complex Materials focuses on the structural determination of crystalline solids with extensive disorder. Well-established methods exist for characterizing the structure of fully crystalline solids or fully disordered materials such as liquids and glasses, but there is a dearth of techniques for the cases in-between, crystalline solids with internal atomic and nanometer scale disorder. Egami and Billinge discuss how to fill the gap using modern tools of structural characterization. This problem is encountered in the structural characterization of a surprisingly wide range of complex materials of interest to modern technology and is becoming increasingly important.

Takeshi Egami received the 2003 Eugene Bertram Warren Diffraction Physics Award for the work described in the book.

The authors received 2010 J. D. Hanawalt Award from the International Union of Crystallography largely based on the success of this book.
Introduces a unique method to study the atomic structure of nanomaterials Lays out the basic theory and methods of this important emerging technique The first edition is considered the seminal text on the subject

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Design Recipes for FPGAs provides a rich toolbox of design techniques and templates to solve practical, every-day problems using FPGAs. Using a modular structure, it provides design techniques and templates at all levels, together with functional code, which you can easily match and apply to your application. Written in an informal and easy to grasp style, this invaluable resource goes beyond the principles of FPGAs and hardware description languages to demonstrate how specific designs can be synthesized, simulated and downloaded onto an FPGA. In addition, the book provides advanced techniques to create real world designs that fit the device required and which are fast and reliable to implement.
Examples are rewritten and tested in Verilog and VHDL Describes high-level applications as examples and provides the building blocks to implement them, enabling the student to start practical work straight away Singles out the most important parts of the language that are needed for design, giving the student the information needed to get up and running quickly

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Produced by microbes on a large scale, methane is an important alternative fuel as well as a potent greenhouse gas. This volume focuses on microbial methane metabolism, which is central to the global carbon cycle. Both methanotrophy and methanogenesis are covered in detail. Topics include isolation and classification of microorganisms, metagenomics approaches, biochemistry of key metabolic enzymes, gene regulation and genetic systems, and field measurements. The state of the art techniques described here will both guide researchers in specific pursuits and educate the wider scientific community about this exciting and rapidly developing field.
Topics include isolation and classification of microorganisms, metagenomics approaches, biochemistry of key metabolic enzymes, gene regulation and genetic systems and field measurements The state-of-the-art techniques described here will both guide researchers in specific pursuits and educate the wider scientific community about this exciting and rapidly developing field

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Private Security and the Law, Fourth Edition, is a unique resource that provides a comprehensive analysis of practices in the security industry as they relate to law, regulation, licensure, and constitutional questions of case and statutory authority. It is an authoritative, scholarly treatise that serves as a solid introduction for students regarding the legal and ethical standards that shape the industry.

The book takes you step-by-step through the analysis of case law as it applies to situations commonly faced by security practitioners. It describes the legal requirements faced by security firms and emphasizes the liability problems common to security operations, including negligence and tortious liability, civil actions frequently litigated, and strategies to avoid legal actions that affect business efficiency. It also examines the constitutional and due-process dimensions of private security both domestically and internationally, including recent cases and trends that are likely to intensify in the future. New features of this edition include: a chapter on the legal implications of private contractors operating in war zones like Afghanistan; updated coverage of statutory authority, as well as state and federal processes of oversight and licensure; and special analysis of public-private cooperative relationships in law enforcement. A historical background helps readers understand the present by seeing the full context of recent developments.

This book will appeal to: students in physical security, security management, and criminal justice programs in traditional and for-profit schools; security professionals; and those working in law enforcement.
Authoritative, scholarly treatise sheds light on this increasingly important area of the law Historical background helps readers understand the present by seeing the full context of recent developments National scope provides crucial parameters to security practitioners throughout the US NEW TO THIS EDITION! A chapter on the legal implications of private contractors operating in war zones like Afghanistan, updated coverage of statutory authority, updated coverage of state and federal processes of oversight and licensure, special analysis of public-private cooperative relationships in law enforcement

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Experiment and Calculation of Reinforced Concrete at Elevated Temperatures

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Concrete as a construction material goes through both physical and chemical changes under extreme elevated temperatures. As one of the most widely used building materials, it is important that both engineers and architects are able to understand and predict its behavior in under extreme heat conditions. Brief and readable, this book provides the tools and techniques to properly analysis the effects of high temperature of reinforced concrete which will lead to more stable, safer structures.

Based on years of the authors research, Reinforced Concrete at Elevated Temperatures four part treatment starts with an unambiguous and thorough exposition of the mechanical behaviors of materials at elevated temperature followed by a discussion of Temperature field of member sections, Mechanical behaviors of members and structures at elevated temperature, ending with Theoretical analysis and practical calculation methods. The book provides unique insight into:

Coupling thermal-mechanical constitutive relation of concrete
Exceptional analyses of beams and columns of rectangular section with three surfaces and two adjacent surfaces exposing to high temperature
Measurement and analysis of redistribution of internal forces of statically indeterminate structure during heating-loading process
Finite element analysis and calculation charts for two-dimensional temperature field of structural members
Finite element analysis and simplified calculation method for reinforced concrete structure at elevated temperature
With this book, engineers and architects can effectively analyze the effect of high temperature on concrete and materials which will lead to better designs of fire resistant and damage evaluation and treatment after fire.
Tools and techniques for analyzing the effects of high temperature on concrete and reinforcement materials Measurement and analysis of redistribution of internal forces of statically indeterminate structure during the heating-loading process Finite element analysis and calculation charts for two-dimensional temperature field of structural members Finite element analysis and simplified calculation method for reinforced concrete structure at elevated temperature

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First published in 1943, Vitamins and Hormones is the longest-running serial published by Academic Press. The Editorial Board now reflects expertise in the field of hormone action, vitamin action, X-ray crystal structure, physiology and enzyme mechanisms.

Under the capable and qualified editorial leadership of Dr. Gerald Litwack, Vitamins and Hormones continues to publish cutting-edge reviews of interest to endocrinologists, biochemists, nutritionists, pharmacologists, cell biologists and molecular biologists. Others interested in the structure and function of biologically active molecules like hormones and vitamins will, as always, turn to this series for comprehensive reviews by leading contributors to this and related disciplines.

This volume focuses on vitamins and the immune system.
Longest running series published by Academic Press Contributions by leading international authorities

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The first edition of Geometric Morphometrics for Biologists has been the primary resource for teaching modern geometric methods of shape analysis to biologists who have a stronger background in biology than in multivariate statistics and matrix algebra. These geometric methods are appealing to biologists who approach the study of shape from a variety of perspectives, from clinical to evolutionary, because they incorporate the geometry of organisms throughout the data analysis. The second edition of this book retains the emphasis on accessible explanations, and the copious illustrations and examples of the first, updating the treatment of both theory and practice. The second edition represents the current state-of-the-art and adds new examples and summarizes recent literature, as well as provides an overview of new software and step-by-step guidance through details of carrying out the analyses.
Contains updated coverage of methods, especially for sampling complex curves and 3D forms and a new chapter on applications of geometric morphometrics to forensics Offers a reorganization of chapters to streamline learning basic concepts Presents detailed instructions for conducting analyses with freely available, easy to use software Provides numerous illustrations, including graphical presentations of important theoretical concepts and demonstrations of alternative approaches to presenting results

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Miriam Zelditch, Donald Swiderski, H. David Sheets

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Machinery Failure Analysis and Troubleshooting

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Practical Machinery Management for Process Plants

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Solve the machinery failure problems costing you time and money with this classic, comprehensive guide to analysis and troubleshooting
Provides detailed, complete and accurate information on anticipating risk of component failure and avoiding equipment downtime Includes numerous photographs of failed parts to ensure you are familiar with the visual evidence you need to recognize Covers proven approaches to failure definition and offers failure identification and analysis methods that can be applied to virtually all problem situations Demonstrates with examples how the progress and results of failure analysis and troubleshooting efforts can be documented and monitored
Failures of machinery in a plant setting can have wide-ranging consequences and in order to stay competitive, corporations across all industries must optimize the efficiency and reliability of their machinery.

Machinery Failure Analysis and Troubleshooting is a trusted, established reference in the field, authored by two well-known authorities on failure and reliability. Structured to teach failure identification and analysis methods that can be applied to almost all problem situations, this eagerly awaited update takes in the wealth of technological advances and changes in approach seen since the last edition published more than a decade ago.

Covering both the engineering detail and management theory, Machinery Failure Analysis and Troubleshooting provides a robust go-to reference and training resource for all engineers and managers working in manufacturing and process plants.
Provides detailed, complete and accurate information on anticipating risk of component failure and avoiding equipment downtime Presents documented failure case studies and analyzes the procedures employed to define events that led to component or systems failure Includes numerous photographs of failed parts to ensure readers are familiar with the visual evidence they need to recognize

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Clinical Pharmacology During Pregnancy is written for clinicians, physicians, midwives, nurses, pharmacists and other medical professionals directly involved in the care of women during pregnancy. This book focuses on the impact of pregnancy on drug disposition and also includes coverage of treatments for diseases of specific body systems as well as essential content on dosing and efficacy.

The broad range of this book encompasses analgesics, antiasthmatics, antidepressants, heart and circulatory drugs, vitamins and herbal supplements, and more. Topics in chemotherapy and substance abuse are covered, as are research issues, including clinical trial design and ethical considerations.
Uses an evidence-based approach for therapeutics during pregnancy Includes a summary of specific medications by indication with up-to-date information on dosing and efficacy in pregnancy for the given indication

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Research Methods in Human Skeletal Biology

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Research Methods in Human Skeletal Biology serves as the one location readers can go to not only learn how to conduct research in general, but how research is specifically conducted within human skeletal biology. It outlines the current types of research being conducted within each sub-specialty of skeletal biology, and gives the reader the tools  to set up a research project in skeletal biology. It also suggests several ideas for potential projects. Each chapter has an inclusive bibliography, which can serve as a good jumpstart for project references. Provides a step-by-step guide to conducting research in human skeletal biology Covers diverse topics (sexing, aging, stature and ancestry estimation) and new technologies (histology, medical imaging, and geometric morphometrics) Excellent accompaniment to existing forensic anthropology or osteology works

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This title provides comprehensive coverage of modern gas chromatography including theory, instrumentation, columns, and applications addressing the needs of advanced students and professional scientists in industry and government laboratories. Chapters are written by recognized experts on each topic. Each chapter offers a complete picture with respect to its topic so researchers can move straight to the information they need without reading through a lot of background information. Individual chapters written by recognized experts The big picture of gas chromatography from theory, to methods, to selected applications Provides references to other sources in associated areas of study to facilitate research Gives access to core data for practical work, comparison of results and decision making

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To provide an interdisciplinary readership with the necessary toolkit to work with micro- and nanofluidics, this book provides basic theory, fundamentals of microfabrication, advanced fabrication methods, device characterization methods and detailed examples of applications of nanofluidics devices and systems. Case studies describing fabrication of complex micro- and nanoscale systems help the reader gain a practical understanding of developing and fabricating such systems. The resulting work covers the fundamentals, processes and applied challenges of functional engineered nanofluidic systems for a variety of different applications, including discussions of lab-on-chip, bio-related applications and emerging technologies for energy and environmental engineering.
The fundamentals of micro- and nanofluidic systems and micro- and nanofabrication techniques provide readers from a variety of academic backgrounds with the understanding required to develop new systems and applications. Case studies introduce and illustrate state-of-the-art applications across areas, including lab-on-chip, energy and bio-based applications. Prakash and Yeom provide readers with an essential toolkit to take micro- and nanofluidic applications out of the research lab and into commercial and laboratory applications.