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Nerve Agents Poisoning and its Treatment in Schematic Figures and Tables

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Organophosphate compounds, first synthesized in the 1800s, have been used for insecticides, pesticides, and in war and terrorism, such as the 1995 Tokyo subway poisoning. This book provides an in-depth examination of the effects of organophosphates and nerve agents and offers therapeutic and prophylactic countermeasures. Beginning with an overview of milestones in the use of toxic chemicals and chemical warfare agents, the formulae and toxicities of compounds are given, along with tables outlining animal toxicities. Data on various compounds inhibitions and subsequent accumulations are also provided. Along with data on organophosphates and nerve agents, possible first aid and medical responses are compared among potential responses in the United States and other countries in the east and west. Using clear schematics and tables, this book provides a detailed account of the most common organophosphates and nerve agents, ideas of how to countermeasure their effects, and offers detailed suggestions for where research needs to proceed in the future. This book will prove useful to students, researchers, and military personnel needing to know more about how to deal with nerve agents.
Dedicated to organophosphates/nerve agent, this book contains tables on toxicities in animals and simple figures useable for brief orientation and education

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The second edition of Agriculture's Ethical Horizon is a carefully considered application of philosophical concepts, such as utilitarianism and positivism, to the practice of agricultural science. Author Robert Zimdahl argues for an approach to agriculture guided by foundational values, and addresses the questions: What are the goals of agricultural and weed science? What should their goals be? How do and how should the practitioners of agriculture address complex ethical questions?

This book engages students, researchers, and professionals across disciplines including horticulture, soil and plant science, entomology, and more, all without requiring a background in philosophy. It examines topics such as scientific truth and myth, moral confidence in agriculture, the relevance of ethics to sustainability, and biotechnology. New to this edition is a chapter examining the raising, housing and slaughter of animals for human food, and a chapter on alternative and organic agricultural systems.
Easily understood by non-philosophers Chapter sidebars highlight important concepts and can be used to engage students in further discussion Companion website includes further teaching aids and a discussion board

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Principles of Data Integration is the first comprehensive textbook of data integration, covering theoretical principles and implementation issues as well as current challenges raised by the semantic web and cloud computing. The book offers a range of data integration solutions enabling you to focus on what is most relevant to the problem at hand. Readers will also learn how to build their own algorithms and implement their own data integration application.

Written by three of the most respected experts in the field, this book provides an extensive introduction to the theory and concepts underlying today's data integration techniques, with detailed, instruction for their application using concrete examples throughout to explain the concepts.

This text is an ideal resource for database practitioners in industry, including data warehouse engineers, database system designers, data architects/enterprise architects, database researchers, statisticians, and data analysts; students in data analytics and knowledge discovery; and other data professionals working at the R&D; and implementation levels.
Offers a range of data integration solutions enabling you to focus on what is most relevant to the problem at hand Enables you to build your own algorithms and implement your own data integration applications

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A Ticking Time Bomb for Reproductive Health

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Obesity is a continuing issue around the world and in many contexts. The growing number of obese people is an increasing concern for those in the medical profession, and obesity can pose specific challenges in relation to fertility and pregnancy. Patients who are obese require specific considerations and knowledge. Bringing together experts from a variety of specialties to examine the issues and challenges of obesity, this book discusses how obesity affects fertility, reproduction, and pregnancy. Beginning with an exploration of the epidemiology of obesity, further chapters focus on specific issues related to obesity and both male and female reproduction, the complications of obesity during pregnancy and labour, and the long term effects of obesity. This is the most comprehensive resource to examine the topic of obesity and reproductive issues, making it invaluable for medical students, professionals, and researchers in public policy and medicine.
Comprehensive examination of fertility issues arising from male and female obesity Clinical knowledge and expertise given to the subjects In-depth examination through 47 chapters of a growing, but often overlooked, issue in fertility and pregnancy

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Tahir A. Mahmood, Sabaratnam Arulkumaran

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The Mediterranean region contains a diverse and interesting climate ranging from areas with permanent glaciers to areas of subtropical, semiarid regions. The region is potentially sensitive to climate change and its progress has environmental, social, and economic implications within and beyond the region. Produced by the Mediterranean Climate Variability and Predictability Research Networking Project, this book reviews the evolution of the Mediterranean climate over the past two millennia with projections further into the twenty-first century as well as examining in detail various aspects of the Mediterranean regions climate including evolution, atmospheric variables, and oceanic and land elements. Integrated with this, the book also considers the social and economic problems or vulnerabilities associated with the region. Written and reviewed by multiple researchers to ensure a high level of information presented clearly, Mediterranean Climate Variables will be an invaluable source of information for geologists, oceanographers, and anyone interested in learning more about the Mediterranean climate.
Written by leading experts in the field Presents clear, compelling, and concise evidence Includes the latest thinking in Mediterranean climate research

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The accelerated globalization of the food supply, coupled with toughening government standards, is putting global food production, distribution, and retail industries under a high-intensity spotlight. High-publicity cases about foodborne illnesses over recent years have heightened public awareness of food safety issues, and momentum has been building to find new ways to detect and identify foodborne pathogens and eliminate food-related infections and intoxications. This extensively revised 4e covers how the incidence and impact of foodborne diseases is determined, foodborne intoxications with an introduction noting common features among these diseases and control measures that are applicable before and after the basic foodstuff is harvested. Provides a summary of the

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Protein Engineering for Therapeutics, Part A

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This volume of Methods in Enzymology looks at Protein Engineering for Therapeutics. The chapters provide an invaluable resource for academics, researchers and students alike. With an international board of authors, this volume is split into sections that cover subjects such as Antibodies, Protein conjugates, Peptides, Enzymes and Scaffolds
Chapters provide an invaluable resource for academics, researchers and students alike Iinternational board of authors This volume is split into sections that cover subjects such as Antibodies, Protein conjugates, Peptides, Enzymes and Scaffolds

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Dental defects may be the physical expression of genetic defects, and so they can often be seen in a variety of syndromes associated with malformations of organs. However, dental defects are often not recognized, identified, nor characterised despite representing a possible diagnostic sign for an undiagnosed condition. This book addresses this gap by providing an understanding of dental genetics and its developmental biology counterpart. With approximately seventy well-illustrated examples, the authors present the clinical oro-facial manifestations accompanying various syndromes, providing the necessary knowledge for diagnostic purposes, as well as giving insight into recent development for each specific condition. The clarity and format of this book make it an ideal support guide both in the clinic and while conducting research.
Comprehensive examination of dento/oro/craniofacial anomalies Well-illustrated examples Presented in a compact, easy to use format

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Agnes Bloch-Zupan, Heddie Sedano, Crispian Scully

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Polyphosphoesters are a multifunctional, environmentally friendly, and cost-efficient material, making them an important subject. The design of this type of material plays a key role in the progress of industry, agriculture, and medicine. This book introduces the chemistry, characterization and application of polyphosphoesters including comprehensive coverage of poly(alkylene H-phosphonate)s, poly(alkylene phosphate)s, poly(alkyl or aryl phosphonate)s, and poly(alkyl phosphite)s and poly(alkyl phosphinite)s. Each polymer is discussed in detail including methods, properties, and applications.

This book is useful for students and practitioners preparing to work, or in the process of working, in the exciting field of polymer chemistry.
Presents a unique look at an important, multifunctional and environmentally friendly material Outlines methods used to prepare different polyphosphoesters Comprehensive examination of the properties of polyphosphoesters

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Cargo Theft, Loss Prevention, and Supply Chain Security

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Cargo Theft, Loss Prevention, and Supply Chain Security outlines steps for identifying the weakest links in the supply chain and customizing a security program to help you prevent thefts and recover losses. Written by one of the worlds leading experts in cargo theft analysis, risk assessment and supply chain security, this is the most comprehensive book available on the topic of cargo theft and loss prevention. Part history of cargo theft, part analysis and part how-to guide, the book is the one source supply chain professionals and students can turn to in order to understand every facet of cargo theft and take steps to prevent losses.This groundbreaking book contains methods of predictive cargo theft modeling, allowing proactive professionals to develop prevention solutions at every step along the supply chain. It provides a complete methodology for use in creating your own customized supply chain security program as well as in-depth analysis of commonly encountered supply chain security problems. It also supplies a massive amount of credible cargo theft statistics and provides solutions and best practices to supply chain professionals who must determine their companys risk and mitigate their losses by adopting customizable security programs. Furthermore, it presents cutting-edge techniques that industry professionals can use to prevent losses and keep their cargo secure at every stage along the supply chain.This book will be of interest to manufacturing, logistics and security professionals including chief security officers, VPs of logistics or supply chain operations, and transportation managers, as well as professionals in any company that manufactures, ships, transports, stores, distributes, secures or is otherwise responsible for bulk product and cargo. Outlines steps you can take to identify the weakest links in the supply chain and customize a security program to help you prevent thefts and recover losses Offers detailed explanations of downstream costs in a way that makes sense - including efficiency losses, customer dissatisfaction, product recalls and more - that dramatically inflate the impact of cargo theft incidents Provides a complete methodology for use in creating your own customized supply chain security program as well as in-depth analysis of commonly encountered supply chain security problems

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Implications and Applications: Animals and Microbes

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This volume on medicinal foods from the sea narrates the bioactive principles of various marine floral (vertebrate and Invertebrate), faunal (Macro and Micro algal) and microbial sources. Contributions from eminent scientists worldwide explain about the latest advance implications in the development and application of marine originated functional foods, as potential pharmaceuticals and medicines for the benefit of humankind by meeting the present nutraceutical demands. The latest important information for food scientists and nutritionists Peer-reviewed articles by a panel of respected scientists The go-to series since 1948

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Nanoparticles in Translational Science and Medicine

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This volume explores some of the most exciting recent advances in basic research on nanoparticles in translational science and medicine and how this knowledge is leading to advances in the various fields. This series provides a forum for discussion of new discoveries, approaches, and ideas Contributions from leading scholars and industry experts Reference guide for researchers involved in molecular biology and related fields

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This is a comprehensive book addressing steroid disorders from hormonal, genetic, psychological, and surgical perspectives. It is meant to educate adult and pediatric endocrinologists, clinical geneticists, genetic counselors, reproductive endocrinologists, neonatologists, urologists, and psychoendocrinologists. It will assist these specialists in the diagnosis and treatment of steroid disorders. The book is written for postgraduate and faculty-level physicians. The content consists of steroid disorders, genetic bases for the disorder and case presentations of each disorder.
Provides a common language for professionals to discuss and diagnose genetic steroid disorders Includes the very latest details on genetic tests and diagnoses Offers a strong understanding of the molecular basis for the diseases and therefore correct diagnosis and treatment of steroid disorders Presents insight into which medications to use based on the genetic makeup of a patient Teaches the best strategies and most effective use of genetic information in the patient counseling setting

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Maria I. New, Oksana Lekarev, Alan Parsa, Tony T. Yuen, Bert O'Malley, Gary D. Hammer

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This second edition of a pioneering technical work in biomedical informatics provides a very readable treatment of the deep computational ideas at the foundation of the field. Principles of Biomedical Informatics, 2nd Edition is radically reorganized to make it especially useable as a textbook for courses that move beyond the standard introductory material. It includes exercises at the end of each chapter, ideas for student projects, and a number of new topics, such as: tree structured data, interval trees, and time-oriented medical data and their use On Line Application Processing (OLAP), an old database idea that is only recently coming of age and finding surprising importance in biomedical informatics a discussion of nursing knowledge and an example of encoding nursing advice in a rule-based system X-ray physics and algorithms for cross-sectional medical image reconstruction, recognizing that this area was one of the most central to the origin of biomedical computing an introduction to Markov processes, and an outline of the elements of a hospital IT security program, focusing on fundamental ideas rather than specifics of system vulnerabilities or specific technologies.

It is simultaneously a unified description of the core research concept areas of biomedical data and knowledge representation, biomedical information access, biomedical decision-making, and information and technology use in biomedical contexts, and a pre-eminent teaching reference for the growing number of healthcare and computing professionals embracing computation in health-related fields.

As in the first edition, it includes many worked example programs in Common LISP, the most powerful and accessible modern language for advanced biomedical concept representation and manipulation.

The text also includes humor, history, and anecdotal material to balance the mathematically and computationally intensive development in many of the topic areas. The emphasis, as in the first edition, is on ideas and methods that are likely to be of lasting value, not just the popular topics of the day. Ira Kalet is Professor Emeritus of Radiation Oncology, and of Biomedical Informatics and Medical Education, at the University of Washington. Until retiring in 2011 he was also an Adjunct Professor in Computer Science and Engineering, and Biological Structure. From 2005 to 2010 he served as IT Security Director for the University of Washington School of Medicine and its major teaching hospitals. He has been a member of the American Medical Informatics Association since 1990, and an elected Fellow of the American College of Medical Informatics since 2011. His research interests include simulation systems for design of radiation treatment for cancer, software development methodology, and artificial intelligence applications to medicine, particularly expert systems, ontologies and modeling.
Develops principles and methods for representing biomedical data, using information in context and in decision making, and accessing information to assist the medical community in using data to its full potential Provides a series of principles for expressing biomedical data and ideas in a computable form to integrate biological, clinical, and public health applications Includes a discussion of user interfaces, interactive graphics, and knowledge resources and reference material on programming languages to provide medical informatics programmers with the technical tools to develop systems

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The relatively new technique of solid phase microextraction (SPME) is an important tool to prepare samples both in the lab and on-site. SPME is a "green" technology because it eliminates organic solvents from analytical laboratory and can be used in environmental, food and fragrance, and forensic and drug analysis. This handbook offers a thorough background of the theory and practical implementation of SPME. SPME protocols are presented outlining each stage of the method and providing useful tips and potential pitfalls. In addition, devices and fiber coatings, automated SPME systems, SPME method development, and In Vivo applications are discussed.

This handbook is essential for its discussion of the latest SPME developments as well as its in depth information on the history, theory, and practical application of the method.
Practical application of Solid Phase Microextraction methods including detailed steps Provides history of extraction methods to better understand the process Suitable for all levels, from beginning student to experienced practitioner

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This Expert Guide gives you the techniques and technologies in embedded multicore to optimally design and implement your embedded system. Written by experts with a solutions focus, this encyclopedic reference gives you an indispensable aid to tackling the day-to-day problems when building and managing multicore embedded systems.

Following an embedded system design path from start to finish, our team of experts takes you from architecture, through hardware implementation to software programming and debug.

With this book you will learn:

What motivates multicore

The architectural options and tradeoffs; when to use what

How to deal with the unique hardware challenges that multicore presents

How to manage the software infrastructure in a multicore environment

How to write effective multicore programs

How to port legacy code into a multicore system and partition legacy software

How to optimize both the system and software

The particular challenges of debugging multicore hardware and software
Examples demonstrating timeless implementation details Proven and practical techniques reflecting the authors expertise built from years of experience and key advice on tackling critical issues

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Dimensionless Physical Quantities in Science and Engineering

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Dimensionless quantities, such as p, e, and f are used in mathematics, engineering, physics, and chemistry. In recent years the dimensionless groups, as demonstrated in detail here, have grown in significance and importance in contemporary mathematical and computer modeling as well as the traditional fields of physical modeling. This book offers the most comprehensive and up to date resource for dimensionless quantities, providing not only a summary of the quantities, but also a clarification of their physical principles, areas of use, and other specific properties across multiple relevant fields. Presenting the most complete and clearly explained single resource for dimensionless groups, this book will be essential for students and researchers working across the sciences.
Includes approximately 1,200 dimensionless quantities Features both classic and newly developing fields Easy to use with clear organization and citations to relevant works

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An Interactive History of the Clean Air Act

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The Clean Air Act of 1970 set out for the United States a basic, yet ambitious, objective to reduce pollution to levels that protect health and welfare. The Act set out state and federal regulations to limit emissions and the Environmental Protection Agency was established to help enforce the regulations. The Act has since had several amendments, notably in 1977 and 1990, and has successfully helped to increase air quality. This book reviews the history of the Clean Air Act of 1970 including the political, business, and scientific elements that went into establishing the Act, emphasizing the importance that scientific evidence played in shaping policy. The analysis then extends to examine the effects of the Act over the past forty years including the Environmental Protection Agencys evolving role and the role of states and industry in shaping and implementing policy. Finally, the book offers best practices to guide allocation of respective government and industry roles to guide sustainable development.

The history and analysis of the Clean Air Act presented in this book illustrates the centrality of scientific analysis and technological capacity in driving environmental policy development. It would be useful for policy makers, environmental scientists, and anyone interested in gaining a clearer understand of the interaction of science and policy.
Offers an overview of the 1970 Clean Air Act and its subsequent effects Highlights the relationship between policy and scientific discovery Extracts lessons from the United States to apply to other policy and national contexts

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Resident Stem Cells and Regenerative Therapy

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In the last 3 decades, stem cells have greatly impacted the scientific and lay communities, providing huge advances in the treatment of devastating human diseases, including myocardial infarction, diabetes, muscular dystrophy, cystic fibrosis, cirrhosis, and osteoporosis. Alongside debates of induced pluripotent stem cells and embryonic stem cells has been the discovery of adult stem cells in many different tissues. While these organ resident or progenitor stem cells offer prospects to contribute to tissue regeneration, they also present challenges because of the complexity of organ structures.

This book will present the main findings to date and the important factors to be considered when considering resident stem cells in regenerative therapies. Chapters on cardiac, brain, neural, liver, kidney, skeletal muscle, bone, pancreatic, skin, and lung resident stem cells will assist in defining the level of success that has been achieved and the direction for the road ahead. With contributions from leading laboratories, open questions related to resident stem cells and regenerative therapies will also be presented for debate.
Highlights basic research in tissue specific stem cells, experiments with animal models and clinical trials that are transforming the field of regeneration Provides a clear understanding of endogenous stem cells, their role in current regenerative therapies, and prospects for future research Reports on the main-stream clinical approaches and in vivo experiments published in primary literature to help categorizes the advances in various aspects of regenerative therapy and illustrate opportunities for clinical applications

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Regina Coeli dos Santos Goldenberg, Antonio Carlos Campos de Carvalho

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This new volume of Current Topics in Developmental Biology covers the area of gametogenesis, with contributions from an international board of authors. The chapters provide a comprehensive set of reviews covering such topics as germline stem cells, signaling modalities during oogenesis in mammals, and genomic imprinting as a parental effect established in mammalian germ cells.
Covers the area of gametogenesis International board of authors Provides a comprehensive set of reviews covering such topics as germline stem cells, signaling modalities during oogenesis in mammals, and genomic imprinting as a parental effect established in mammalian germ cells