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First published in 1943, Vitamins and Hormones is the longest-running serial published by Academic Press.

Under the capable and qualified editorial leadership of Dr. Gerald Litwack, Vitamins and Hormones continues to publish cutting-edge reviews of interest to endocrinologists, biochemists, nutritionists, pharmacologists, cell biologists and molecular biologists. Others interested in the structure and function of biologically active molecules like hormones and vitamins will, as always, turn to this series for comprehensive reviews by leading contributors to this and related disciplines.

This volume focuses on hedgehog signaling.
Contributions from leading authorities Informs and updates on all the latest developments in the field

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The growth of implant and fixed prosthodontics practices in dentistry has created a rapidly increasing demand for advanced ceramics and ceramic processes. Innovations in ceramics and ceramic processes are vital to ensure reliable and affordable dental-restoration solutions with aesthetically pleasing outcomes.

The work aims to engage the bioceramics and engineering communities to meet the challenges of modern dental restoration using advanced ceramics. Incorporating fundamental science, advanced engineering concepts, and clinical outcomes, the work is suitable for bioceramicists, ceramics manufacturers, dental clinicians and biologists.
State-of-the-art-coverage encompasses bioresorbable ceramics for bone regeneration and bioactivating surfaces of inert, high-strength ceramics for implantation, keeping research knowledge appropriately updated Discusses transition from the baseline stable and physically stiff ceramics research into engineering of highly coherent laminate composites for prosthetic crowns and bridges Showcases current feasible techniques for producing, in cost-effective and materials-saving ways, long-lasting individualized ceramic components with biocompatibility, complexity and high precision

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The 4e of The Science and Technology of Rubber provides a broad survey of elastomers with special emphasis on materials with a rubber-like elasticity. As in previous editions, the emphasis remains on a unified treatment of the material, exploring chemical aspects such as elastomer synthesis and curing, through recent theoretical developments and characterization of equilibrium and dynamic properties, to the final applications of rubber, including tire engineering and manufacturing. Updated material stresses the continuous relationship between ongoing research in synthesis, physics, structure and mechanics of rubber technology and industrial applications. Special attention is paid to recent advances in rubber-like elasticity theory and new processing techniques for elastomers. Exciting new developments in green tire manufacturing and tire recycling are covered. Provides a complete survey of elastomers for engineers and researchers in a unified treatment: from chemical aspects like elastomer synthesis and curing to the final applications of rubber, including tire engineering and manufacturing Contains important updates to several chapters, including elastomer synthesis, characterization, viscoelastic behavior, rheology, reinforcement, tire engineering, and recycling Includes a new chapter on the burgeoning field of bioelastomers

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This volume explores some of the most exciting recent advances in basic research on animal models of molecular pathology. This series provides a forum for discussion of new discoveries, approaches, and ideas Contributions from leading scholars and industry experts Reference guide for researchers involved in molecular biology and related fields

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Get a comprehensive and detailed insight into the Evolved Packet Core (EPC) with this clear, concise and authoritative guide a fully updated second edition that covers the latest standards and industry developments. The latest additions to the Evolved Packet System (EPS) including e.g. Positioning, User Data Management, eMBMS, SRVCC, VoLTE, CSFB. A detailed description of the nuts and bolts of EPC that are required to really get services up and running on a variety of operator networks. An in-depth overview of the EPC architecture and its connections to the wide variety of network accesses, including LTE, LTE-Advanced, WCDMA/HSPA, GSM, WiFi, etc. The most common operator scenarios of EPS and the common issues faced in their design. The reasoning behind many of the design decisions taken in EPC, in order to understand the full details and background of the all-IP core

NEW CONTENT TO THIS EDITION

150+ New pages, new illustrations and call flows Covers 3GPP Release 9, 10 and 11 in addition to release 8 Expanded coverage on Diameter protocol, interface and messages Architecture overview Positioning User Data Management eMBMS (LTE Broadcasting) H(e)NodeB/Femto Cells LIPA/SIPTO/Breakout architectures Deployment Scenarios WiFi interworking VoLTE/MMTel, CS fallback and SRVCC
SAE is the core network that supports LTE, the next key stage in development of the UMTS network to provide mobile broadband. It aims to provide an efficient, cost-effective solution for the ever-increasing number of mobile broadband subscribers There is no other book on the market that covers the entire SAE network architecture; this book summarizes the important parts of the standards, but goes beyond mere description and offers real insight and explanation of the technology Fully updated with the latest developments since the first edition published, and now including additional material and insights on industry trends and views regarding future potential applications of SAE

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This book explains how UHF tags and readers communicate wirelessly. It gives an understanding of what limits the read range of a tag, how to increase it (and why that might result in breaking the law), and the practical things that need to be addressed when designing and implementing RFID technology. Avoiding heavy math but giving breadth of coverage with the right amount of detail, it is an ideal introduction to radio communications for engineers who need insight into how tags and readers work.

New to this edition:

Examples of near-metal antenna techniques

Discussion of the wakeup challenge for battery-assisted tags, with a BAT architecture example

Latest development of protocols: EPC Gen 1.2.0

Update 18000-6 discussion with battery-assisted tags, sensor tags, Manchester tags and wakeup provisions
Named a 2012 Notable Computer Book for Computer Systems Organization by Computing Reviews The only book to give an understanding of radio communications, the underlying technology for radio frequency identification (RFID) Praised for its readability and clarity, it balances breadth and depth of coverage New edition includes latest developments in chip technology, antennas and protocols

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Providing fundamental knowledge necessary to understand graphenes atomic structure, band-structure, unique properties and an overview of groundbreaking current and emergent applications, this new handbook is essential reading for materials scientists, chemists and physicists.Since the 2010 physics Nobel Prize awarded to Geim and Novosolev for their groundbreaking work isolating graphene from bulk graphite, there has been a huge surge in interest in the area. This has led to a large number of news books on graphene. However, for such a vast inflow of new entrants, the current literature is surprisingly slight, focusing exclusively on current research or books on previous "hot topic" allotropes of carbon.This book covers fundamental groundwork of the structure, property, characterization methods and applications of graphene, along with providing the necessary knowledge of graphenes atomic structure, how it relates to its band-structure and how this in turn leads to the amazing properties of graphene. And so it provides new graduate students and post-docs with a resource that equips them with the knowledge to undertake their research. Discusses graphenes fundamental structure and properties, acting as a time-saving handbook for validated research Demonstrates 100+ high-quality graphical representations, providing the reader with clear images to convey complex situations Reviews characterization techniques relevant to grapheme, equipping the reader with experimental knowledge relevant for practical use rather than just theoretical understanding

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Jamie H. Warner, Franziska Schaffel, Mark Rummeli, Alicja Bachmatiuk

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Caenorhabditis elegans: Cell Biology and Physiology

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The second part of an updated edition of the classic Methods in Cell Biology, Volume 48, this book emphasizes diverse methods and technologies needed to investigate C. elegans, both as an integrated organism and as a model system for research inquiries in cell, developmental, and molecular biology, as well as in genetics and pharmacology. By directing its audience to tried-and-true and cutting-edge recipes for research, this comprehensive collection is intended to guide investigators of C. elegans for years to come.
Diverse, up-to-date techniques covered will be useful to the broadening community of C. elegans researchers for years to come Chapters written by leaders in the field Tried and true methods deliver busy researchers a one-stop compendium of essential protocols

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Proteomic and Metabolomic Approaches to Biomarker Discovery

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Proteomic and Metabolomic Approaches to Biomarker Discovery demonstrates how to leverage biomarkers to improve accuracy and reduce errors in research. Disease biomarker discovery is one of the most vibrant and important areas of research today, as the identification of reliable biomarkers has an enormous impact on disease diagnosis, selection of treatment regimens, and therapeutic monitoring. Various techniques are used in the biomarker discovery process, including techniques used in proteomics, the study of the proteins that make up an organism, and metabolomics, the study of chemical fingerprints created from cellular processes.

Proteomic and Metabolomic Approaches to Biomarker Discovery is the only publication that covers techniques from both proteomics and metabolomics and includes all steps involved in biomarker discovery, from study design to study execution. The book describes methods, and presents a standard operating procedure for sample selection, preparation, and storage, as well as data analysis and modeling. This new standard effectively eliminates the differing methodologies used in studies and creates a unified approach. Readers will learn the advantages and disadvantages of the various techniques discussed, as well as potential difficulties inherent to all steps in the biomarker discovery process.

A vital resource for biochemists, biologists, analytical chemists, bioanalytical chemists, clinical and medical technicians, researchers in pharmaceuticals, and graduate students, Proteomic and Metabolomic Approaches to Biomarker Discovery provides the information needed to reduce clinical error in the execution of research.
Describes the use of biomarkers to reduce clinical errors in research Includes techniques from a range of biomarker discoveries Covers all steps involved in biomarker discovery, from study design to study execution

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Advances in Botanical Research publishes in-depth and up-to-date reviews on a wide range of topics in plant sciences. The series features a wide range of reviews by recognized experts on all aspects of plant genetics, biochemistry, cell biology, molecular biology, physiology and ecology. This thematic volume features reviews on The Genomics of Cyanobacteria. Chapters by internationally renowned researchers share the most up-to-date knowledge on cyanobacteria Even if you have no previous background in the subject, the book's clear language and illustrations tell you what you need to know about the biology and genomics of cyanobacteria and it highlights important directions for future research An essential book for students and researchers

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In this 2nd edition of Micro-Drops and Digital Microfluidics, Jean Berthier explores the fundamentals and applications of digital microfluidics, enabling engineers and scientists to design this important enabling technology into devices and harness the considerable potential of digital microfluidics in testing and data collection.

This book describes the most recent developments in digital microfluidics, with a specific focus on the computational, theoretical and experimental study of microdrops.

Unique in its emphasis on digital microfluidics and with diverse applications ranging from drug delivery to point-of-care diagnostic chips, organic synthesis to microreactors, Micro-Drops and Digital Microfluidics meets the needs of audiences across the fields of bioengineering and biotechnology, and electrical and chemical engineering.
Authoritative reporting on the latest changes in microfluidic science, where microscopic liquid volumes are handled as ""microdrops"" and separately from ""nanodrops." A methodical examination of how liquid microdrops behave in the complex geometries of modern miniaturized systems and interact with different morphological (micro-fabricated, textured) solid substrates A thorough explanation of how capillary forces act on liquid interfaces in contact with micro-fabricated surfaces Analysis of how droplets can be manipulated, handled, or transported using electric fields (electrowetting), acoustic actuation (surface acoustic waves), or by a carrier liquid (microflow) A fresh perspective on the future of microfluidics

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The commercial PVF film Tedlar was first trademarked by DuPont 50 years ago. Since that time it has established itself as a polymer with excellent resistance to sunlight degradation (UV resistance), thermal stability, chemical attack, water absorption, and solvents. These properties, together with a high solar energy transmittance rate, have led to it becoming established worldwide as the number one choice for the backsheets of photovoltaic solar panels, and a fire-retardent coating used in aircraft.

This book is the first and only handbook that describes polyvinyl fluoride preparation, technology, processing, fabrication and applications making it essential reading for engineers and scientists working in industry sectors where PVF is utilized.
Complete guide to the applications of polyvinyl fluoride in photovoltaics, aerospace, signage, etc. Technology guide for processing and fabrication of PVF films Reference for properties and characteristics of PVF films The only book available that focuses on PVF properties, processing and applications

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This book provides the bridge between engineering design and medical device development. There is no single text that addresses the plethora of design issues a medical devices designer meets when developing new products or improving older ones. It addresses medical devices' regulatory (FDA and EU) requirements--some of the most stringent engineering requirements globally. Engineers failing to meet these requirements can cause serious harm to users as well as their products commercial prospects. This Handbook shows the essential methodologies medical designers must understand to ensure their products meet requirements. It brings together proven design protocols and puts them in an explicit medical context based on the author's years of academia (R&D; phase) and industrial (commercialization phase) experience. This design methodology enables engineers and medical device manufacturers to bring new products to the marketplace rapidly.
The medical device market is a multi-billion dollar industry. Every engineered product for this sector, from scalpelsstents to complex medical equipment, must be designed and developed to approved procedures and standards. This book shows how Covers US, and EU and ISO standards, enabling a truly international approach, providing a guide to the international standards that practicing engineers require to understand Written by an experienced medical device engineers and entrepreneurs with products in the from the US and UK and with real world experience of developing and commercializing medical products

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Subsea Pipeline Design, Analysis, and Installation

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As deepwater wells are drilled to greater depths, pipeline engineers and designers are confronted with new problems such as water depth, weather conditions, ocean currents, equipment reliability, and well accessibility. Subsea Pipeline Design, Analysis and Installation is based on the authors' 30 years of experience in offshore. The authors provide rigorous coverage of the entire spectrum of subjects in the discipline, from pipe installation and routing selection and planning to design, construction, and installation of pipelines in some of the harshest underwater environments around the world. All-inclusive, this must-have handbook covers the latest breakthroughs in subjects such as corrosion prevention, pipeline inspection, and welding, while offering an easy-to-understand guide to new design codes currently followed in the United States, United Kingdom, Norway, and other countries. Gain expert coverage of international design codes Understand how to design pipelines and risers for today's deepwater oil and gas Master critical equipment such as subsea control systems and pressure piping

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Theory and Applications of Ligand Binding, ELISA and Related Techniques

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The fourth edition of The Immunoassay Handbook provides an excellent, thoroughly updated guide to the science, technology and applications of ELISA and other immunoassays, including a wealth of practical advice. It encompasses a wide range of methods and gives an insight into the latest developments and applications in clinical and veterinary practice and in pharmaceutical and life science research.

Highly illustrated and clearly written, this award-winning reference work provides an excellent guide to this fast-growing field. Revised and extensively updated, with over 30% new material and 77 chapters, it reveals the underlying common principles and simplifies an abundance of innovation.

The Immunoassay Handbook reviews a wide range of topics, now including lateral flow, microsphere multiplex assays, immunohistochemistry, practical ELISA development, assay interferences, pharmaceutical applications, qualitative immunoassays, antibody detection and lab-on-a-chip.

This handbook is a must-read for all who use immunoassay as a tool, including clinicians, clinical and veterinary chemists, biochemists, food technologists, environmental scientists, and students and researchers in medicine, immunology and proteomics. It is an essential reference for the immunoassay industry.

Provides an excellent revised guide to this commercially highly successful technology in diagnostics and research, from consumer home pregnancy kits to AIDS testing.www.immunoassayhandbook.com is a great resource that we put a lot of effort into. The content is designed to encourage purchases of single chapters or the entire book.

David Wild is a healthcare industry veteran, with experience in biotechnology, pharmaceuticals, medical devices and immunodiagnostics, which remains his passion. He worked for Amersham, Eastman-Kodak, Johnson & Johnson, and Bristol-Myers Squibb, and consulted for diagnostics and biotechnology companies. He led research and development programs, design and construction of chemical and biotechnology plants, and integration of acquired companies. Director-level positions included Research and Development, Design Engineering, Operations and Strategy, for billion dollar businesses. He retired from full-time work in 2012 to focus on his role as Editor of The Immunoassay Handbook, and advises on product development, manufacturing and marketing.
Provides a unique mix of theory, practical advice and applications, with numerous examples Offers explanations of technologies under development and practical insider tips that are sometimes omitted from scientific papers Includes a comprehensive troubleshooting guide, useful for solving problems and improving assay performancee Provides valuable chapter updates, now available on www.immunoassayhandbook.com

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The Dictionary of Cell and Molecular Biology

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The Dictionary of Cell and Molecular Biology, Fifth Edition, provides definitions for thousands of terms used in the study of cell and molecular biology. The headword count has been expanded to 12,000 from 10,000 in the Fourth Edition. Over 4,000 headwords have been rewritten. Some headwords have second, third, and even sixth definitions, while fewer than half are unchanged. Many of the additions were made to extend the scope in plant cell biology, microbiology, and bioinformatics. Several entries related to specific pharmaceutical compounds have been removed, while some generic entries (alpha blockers, NSAIDs, and tetracycline antibiotics, for example), and some that are frequently part of the experimentalists toolkit and probably never used in the clinic, have been retained. The Appendix includes prefixes for SI units, the Greek alphabet, useful constants, and single-letter codes for amino acids. Thoroughly revised and expanded by over 20% with over 12,000 entries in cellular and molecular biology Includes expanded coverage of terms, including plant molecular biology, microbiology and biotechnology areas Consistently provides the most complete short definitions of technical terminology for anyone working in life sciences today Features extensive cross-references  Provides multiple definitions, notes on word origins, and other useful features

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Recent Trends in Medicinal Plants Research

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Plants and other living organisms have great potential to treat human disease. There are two distinct types of biomedical research that seek to develop this potential. One type of research explores the value of medicinal plants as traditionally used and studies of these plants have the potential to determine which plants are most potent, optimize dosages and dose forms, and identify safety risks. Another type of research uses bioassays to identify single molecules from plants that have interesting bioactivities in isolation and might be useful lead compounds for the development of pharmaceutical drugs.

This new volume of Advances in Botanical Research covers the recent trends in Medicinal Plants Research over 11 chapters. Topics that are covered include Development of Drugs from Plants Regulation and Evaluation, Chinese Herbal Medicines for Rheumatoid Arthritis, and Taxol, camptothecin and beyond for cancer therapy.
Covers the recent trends in medicinal plants research over 11 chapters Topics that are covered include Development of Drugs from Plants Regulation and Evaluation, Chinese Herbal Medicines for Rheumatoid Arthritis, and Taxol, camptothecin and beyond for cancer therapy

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This new volume of Current Topics in Developmental Biology covers the area of Planar Cell Polarity with contributions from an international board of authors. The 12 chapters provide a comprehensive set of reviews covering such topics as PCP in Zebra fish, the role of Dishevelled in PCP regulation, and PCP in axon pathfinding.
Covers the area of planar cell polarity International board of authors 12 chapters provide a comprehensive set of reviews covering such topics as planar cell polarity in Zebrafish, the role of disheveled in planar cell polarity regulation, and planar cell polarity in axon path finding

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A best seller since 1966, Purification of Laboratory Chemicals keeps engineers, scientists, chemists, biochemists and students up to date with the purification of the chemical reagents with which they work, the processes for their purification, and guides readers on critical safety and hazards for the safe handling of chemicals and processes. The Seventh Edition is fully updated and provides expanded coverage of the latest commercially available chemical products and processing techniques, safety and hazards: over 200 pages of coverage of new commercially available chemicals since the previous edition.
The only comprehensive chemical purification reference, a market leader since 1966, Amarego delivers essential information for research and industrial chemists, pharmacists and engineers: '... (it) will be the most commonly used reference book in any chemical or biochemical laboratory' (MDPI Journal) An essential lab practice and proceedures manual. Improves efficiency, results and safety by providing critical information for day-to-day lab and processing work. Improved, clear organization and new indexing delivers accurate, reliable information on processes and techniques of purification along with detailed physical properties The Sixth Edition has been reorganised and is fully indexed by CAS Registry Numbers; compounds are now grouped to make navigation easier; literature references for all substances and techniques have been added; ambiguous alternate names and cross references removed; new chemical products and processing techniques are covered; hazards and safety remain central to the book

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Advances in Immunology, a long-established and highly respected publication, presents current developments as well as comprehensive reviews in immunology. Articles address the wide range of topics that comprise immunology, including molecular and cellular activation mechanisms, phylogeny and molecular evolution, and clinical modalities. Edited and authored by the foremost scientists in the field, each volume provides up-to-date information and directions for the future.
Contributions from leading authorities Informs and updates on all the latest developments in the field