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Written by two experienced penetration testers the material presented discusses the basics of the OS X environment and its vulnerabilities. Including but limited to; application porting, virtualization utilization and offensive tactics at the kernel, OS and wireless level. This book provides a comprehensive in-depth guide to exploiting and compromising the OS X platform while offering the necessary defense and countermeasure techniques that can be used to stop hackers

As a resource to the reader, the companion website will provide links from the authors, commentary and updates.
Provides relevant information including some of the latest OS X threats Easily accessible to those without any prior OS X experience Useful tips and strategies for exploiting and compromising OS X systems Includes discussion of defensive and countermeasure applications and how to use them Covers mobile IOS vulnerabilities

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Alijohn Ghassemlouei, Robert Bathurst, Russ Rogers

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Agile Data Warehousing Project Management

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Business Intelligence Systems Using Scrum

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You have to make sense of enormous amounts of data, and while the notion of agile data warehousing might sound tricky, it can yield as much as a 3-to-1 speed advantage while cutting project costs in half. Bring this highly effective technique to your organization with the wisdom of agile data warehousing expert Ralph Hughes.

Agile Data Warehousing Project Management will give you a thorough introduction to the method as you would practice it in the project room to build a serious data mart. Regardless of where you are today, this step-by-step implementation guide will prepare you to join or even lead a team in visualizing, building, and validating a single component to an enterprise data warehouse.
Provides a thorough grounding on the mechanics of Scrum as well as practical advice on keeping your team on track Includes strategies for getting accurate and actionable requirements from a teams business partner Revolutionary estimating techniques that make forecasting labor far more understandable and accurate Demonstrates a blends of Agile methods to simplify team management and synchronize inputs across IT specialties Enables you and your teams to start simple and progress steadily to world-class performance levels

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The Advances in Inorganic Chemistry presents timely and informative summaries of the current progress in a variety of subject areas within inorganic chemistry, ranging from bio-inorganic to solid state studies. This acclaimed serial features reviews written by experts in the field and serves as an indispensable reference to advanced researchers. Each volume contains an index, and each chapter is fully referenced. The Advances in Inorganic Chemistry presents timely and informative summaries of the current progress in a variety of subject areas within inorganic chemistry, ranging from bio-inorganic to solid state studies

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Rudi van Eldik, Ivana Ivanovic-Burmacovic

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Established in 1960, Advances in Heterocyclic Chemistry is the definitive serial in the areaone of great importance to organic chemists, polymer chemists and many biological scientists. Written by established authorities in the field, the comprehensive reviews combine descriptive chemistry and mechanistic insight and yield an understanding of how the chemistry drives the properties. Established in 1960, Advances in Heterocyclic Chemistry is the definitive serial in the area - one of great importance to organic chemists, polymer chemists and many biological scientists Written by established authorities in the field, the comprehensive reviews combine descriptive chemistry and mechanistic insight and yield an understanding of how the chemistry drives the properties

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Advances in Heat Transfer fills the information gap between regularly scheduled journals and university-level textbooks by providing in-depth review articles over a broader scope than in journals or texts. The articles, which serve as a broad review for experts in the field, will also be of great interest to non-specialists who need to keep up-to-date with the results of the latest research. This serial is essential reading for all mechanical, chemical and industrial engineers working in the field of heat transfer, graduate schools or industry. Advances in Heat Transfer fills the information gap between regularly scheduled journals and university-level textbooks by providing in-depth review articles over a broader scope than in journals or texts Of great interest to non-specialists who need to keep up-to-date with the results of the latest research Essential reading for all mechanical, chemical and industrial engineers working in the field of heat transfer, graduate schools or industry

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Ephraim M. Sparrow, Young I. Cho, John Patrick Abraham, John M. Gorman

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Established in 1960, Advances in Heterocyclic Chemistry is the definitive serial in the areaone of great importance to organic chemists, polymer chemists and many biological scientists. Written by established authorities in the field, the comprehensive reviews combine descriptive chemistry and mechanistic insight and yield an understanding of how the chemistry drives the properties. Established in 1960, Advances in Heterocyclic Chemistry is the definitive serial in the areaone of great importance to organic chemists, polymer chemists and many biological scientists. Written by established authorities in the field, the comprehensive reviews combine descriptive chemistry and mechanistic insight and yield an understanding of how the chemistry drives the properties.

# data[].attributes.description
Established in 1960, Advances in Heterocyclic Chemistry is the definitive serial in the areaone of great importance to organic chemists, polymer chemists and many biological scientists. Written by established authorities in the field, the comprehensive reviews combine descriptive chemistry and mechanistic insight and yield an understanding of how the chemistry drives the properties. Provides up-to-date material on a fast-growing and highly topical subject area Contains the latest research covering a wide variety of heterocyclic topics Written by leading authorities and designed as a handbook for students and industry and academic researchers

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Since its first volume in 1960, Advances in Computers has presented detailed coverage of innovations in computer hardware, software, theory, design, and applications. It has also provided contributors with a medium in which they can explore their subjects in greater depth and breadth than journal articles usually allow. As a result, many articles have become standard references that continue to be of sugnificant, lasting value in this rapidly expanding field.
In-depth surveys and tutorials on new computer technology Well-known authors and researchers in the field Extensive bibliographies with most chapters Many of the volumes are devoted to single themes or subfields of computer science

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Since its first volume in 1960, Advances in Computers has presented detailed coverage of innovations in computer hardware, software, theory, design, and applications. It has also provided contributors with a medium in which they can explore their subjects in greater depth and breadth than journal articles usually allow. As a result, many articles have become standard references that continue to be of sugnificant, lasting value in this rapidly expanding field.
In-depth surveys and tutorials on new computer technology Well-known authors and researchers in the field Extensive bibliographies with most chapters Many of the volumes are devoted to single themes or subfields of computer science

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Advances in Carbohydrate Chemistry and Biochemistry

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Since its inception in 1945, this serial has provided critical and integrating articles written by research specialists that integrate industrial, analytical, and technological aspects of biochemistry, organic chemistry, and instrumentation methodology in the study of carbohydrates. The articles provide a definitive interpretation of the current status and future trends in carbohydrate chemistry and biochemistry.
Features contributions from leading authorities and industry experts Informs and updates on all the latest developments in the field

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There has been major growth in understanding immune suppression mechanisms and its relationship to cancer progression and therapy. This book highlights emerging new principles of immune suppression that drive cancer, and it offers radically new ideas about how therapy can be improved by attacking these principles. Following work that firmly establishes immune escape as an essential trait of cancer, recent studies have now defined specific mechanisms of tumor immune suppression. It also demonstrates how attacking tumors with molecular targeted therapeutics or traditional chemotherapeutic drugs can produce potent anti-tumor effects in preclinical models. This book provides basic, translational, and clinical cancer researchers with an indispensable overview of immune escape as a critical trait in cancer and how applying specific combinations of immunotherapy and chemotherapy to attack this trait may radically improve the treatment of advanced disease.
Offers a synthesis of concepts that are useful to cancer immunologists and pharmacologists, who tend to work in disparate fields with little cross-communication Drs. Prendergast and Jaffee are internationally recognized leaders in cancer biology and immunology who have created a unique synthesis of fundamental and applied concepts in this important new area of cancer research Summarizes the latest insights into how immune escape defines an essential trait of cancer Includes numerous illustrations, including how molecular-targeted therapeutic drugs or traditional chemotherapy can be combined with immunotherapy to improve anti-tumor efficacy and how reversing immune suppression by the tumor can cause tumor regression

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George C. Prendergast, Elizabeth M. Jaffee

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Dependable and Secure Systems Engineering

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Since its first volume in 1960, Advances in Computers has presented detailed coverage of innovations in computer hardware, software, theory, design, and applications. It has also provided contributors with a medium in which they can explore their subjects in greater depth and breadth than journal articles usually allow. As a result, many articles have become standard references that continue to be of sugnificant, lasting value in this rapidly expanding field.
In-depth surveys and tutorials on new computer technology Well-known authors and researchers in the field Extensive bibliographies with most chapters Many of the volumes are devoted to single themes or subfields of computer science

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Translational Approaches from Preclinical Studies to Clinical Implementation

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Gene therapy as a treatment for cancer is at a critical point in its evolution. Exciting new developments in gene targeting and vector technology, coupled with results from the first generation of preclinical and clinical studies have led to the design and testing of new therapeutic approaches. The Third Edition of Gene Therapy of Cancer provides crucial updates on the basic and applied sciences of gene therapy. It offers a comprehensive assessment of the field including the areas of suicide gene therapy, oncogene and suppressor gene targeting, immunotherapy, drug resistance gene therapy, and the genetic modification of stem cells. Researchers at all levels of development, from basic laboratory investigators to clinical practitioners, will find this book to be instructive.

Cancer gene therapy, like cancer therapy in general, is evolving rapidly, testing new concepts, targets and pathways, evoking new technologies, and passing new regulatory hurdles. Its essence, however, has not changed: the hope and challenges of returning altered genes to normal, using targeted gene expression to alter the function of both tumor and microenvironment, and in some cases normal cells, and delivering functionally important genes to specific cell types to increase sensitivity to killing or to protect normal cells from cancer therapies.

In some instances, gene therapy for cancer forms a continuum from gene repair through the use of molecularly modified cells; the use of viral and non-viral vector based gene delivery to both tumor and tumor microenvironment; the use of viral and gene based vaccines; and development of new gene-based therapeutics. The unique mechanistically chosen vector platforms are at the heart of this technology because they allow for direct and selective cell death and transient to sustained delivery of vaccine molecules or molecules that affect the microenvironment, vasculature, or the immune response.
Explains the underlying cancer biology necessary for understanding proposed therapeutic approaches Presents in-depth description of targeting systems and treatment strategies Covers the breadth of gene therapy approaches including immunotherapeutic, drug resistance,oncolytic viruses, as well as regulatory perspectives from both the NCI and FDA

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Biomass Gasification, Pyrolysis and Torrefaction

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Biomass is the most widely used non-fossil fuel in the world. Biomass resources show a considerable potential in the long-term given the increasing proliferation of dedicated energy crops for biofuels. The second edition of Biomass Gasification and Pyrolysis is enhanced with new topics, such as torrefaction and cofiring, making it a versatile resource that not only explains the basic principles of energy conversion systems, but also provides valuable insight into the design of biomass conversion systems. This book will allow professionals, such as engineers, scientists, and operating personnel of biomass gasification, pyrolysis or torrefaction plants, to gain a better comprehension of the basics of biomass conversion. The author provides many worked out design problems, step-by-step design procedures and real data on commercially operating systems. With a dedicated focus on the design, analysis, and operational aspects of biomass gasification, pyrolysis, and torrefaction, Biomass Gasification, Pyrolysis and Torrefaction, Second Edition offers comprehensive coverage of biomass in its gas, liquid, and solid states in a single easy-to-access source.
Contains new and updated step-by-step process flow diagrams, design data and conversion charts, and numerical examples with solutions Includes chapters dedicated to evolving torrefaction technologies, practicing option of biomass cofiring, and biomass conversion economics Expanded coverage of syngas and other Fischer-Tropsch alternatives Spotlights advanced processes such as supercritical water gasification and torrefaction of biomass Provides available research results in an easy-to-use design methodology

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This book bridges the technology and business aspects of thermoplastics, providing a guide designed for engineers working in real-world industrial settings. The author explores the criteria for material selection, provides a detailed guide to each family of thermoplastics, and also explains the various processing options for each material type.

More than 30 families of thermoplastics are described with information on their advantages and drawbacks, special grades, prices, transformation processes, applications, thermal behaviour, technological properties (tenacity, friction, dimensional stability), durability (ageing, creep, fatigue), chemical and fire behaviour, electrical properties, and joining possibilities. Biron explores the technological properties and economics of the major thermoplastics and reinforced thermoplastics, such as polyethylene, and emerging polymers such as polybenzimidazole, Thermoplastic Elastomers (TPEs) and bioplastics.

In the second edition, a new section plastics solutions for practical problems provides over 25 case studies illustrating a wide range of design and production challenges across the spectrum of thermoplastics, from metal and glass replacement solutions, to fire retardant plastics and antimicrobials. In addition, Biron provides major new material on bioplastics and wood plastic composites (WPCs), and fully updated data throughout.
Combining materials data, information on processing techniques, and economic aspects (pricing), Biron provides a unique end-to-end approach to the selection and use of materials in the plastics industry and related sectors Includes a new section of case studies, illustrating best practice across a wide range of applications and industry sectors New material on bioplastics and sustainable composites

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Immune Biology of Allogeneic Hematopoietic Stem Cell Transplantation

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Immune Biology of Allogeneic Hematopoietic Stem Cell Transplantation provides clinical and scientific researchers with a deep understanding of the current research in this field and the implications for translational practice. By providing an overview of the immune biology of HSCT, an explanation of immune rejection, and detail on antigens and their role in HSCT success, this book embraces biologists and clinicians who need a broad view of the deeply complex processes involved. It then moves on to discuss the immunobiology mechanisms that influence graft-versus-host disease (GVHD), graft-versus-leukemia (GVL) effect, and transplantation success. Using illustrative figures, highlighting key issues, describing recent successes and discussing unanswered questions, this book sums up the current state of HSCT to enhance the prospects for the future.

Allogeneic HSCT is a medical procedure in which a patient receives blood-forming stem cells from a genetically similar but not identical donor. This procedure is commonly performed for people with diseases of the blood, bone marrow, or certain cancers, but it remains risky with many possible complications. As such, experimental practice is reserved for preclinical animal models including the mouse and dog.

These animal models have been essential in developing transplant protocols, including preclinical testing of conditioning regimens, treatment of GVHD, and understanding the pathology of GVHD as well as the immunological mechanisms of GVHD and GVL effect. However, recent research has revealed significant species differences between humans and animal models that must be considered when relating animal model studies to clinical allogeneic HSCT scenarios.
Brings together perspectives leading laboratories and clinical research groups to highlight advances from bench to the bedside Guides readers through the caveats that must be considered when drawing conclusions from studies with animal models before correlating to clinical allogeneic HSCT scenarios Categorizes the published advances in various aspects of immune biology of allegeneic HSCT to illustrate opportunities for clinical applications

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Public Finance remains the premier textbook on the normative theory of government policy, with the third edition propelling into the twenty-first century its examination of what government ought to be doing instead of what it is doing.

The welfare aspects of public economics receive extensively renewed examination in this third edition. With four new chapters and other significant revisions, it presents detailed and comprehensive coverage of theoretical literature, empirical work, environmental issues, social insurance, behavioral economics, and international tax issues. With increased emphasis on the European Union, it is rigid enough for use by PhDs while being accessible to students less well trained in math.
Moves skillfully from explaining normative theory to applying it in mathematically compact and precise terms Adds new chapters on social insurance, medical care, social security pensions, behavioral public economics, and international public finance Includes new pedagogical supplements, including end-of-chapter questions and answers Emphasizes European examples

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The Atlas of Drosophila Morphology: Wild-type and Classical Mutants is the guide every Drosophila researcher wished they had when first learning genetic markers, and the tool they wish they had now as a handy reference in their lab research. Previously, scientists had only poor-quality images or sketches to work with, and then scattered resources online - but no single visual resource quickly at their fingertips when explaining markers to new members of the lab, or selecting flies to do their genetic crosses, or hybrids.

This alphabetized guide to Drosophila genetic markers lays flat in the lab for easy referencing. It contains high-resolution images of flies and the appropriate marker on the left side of each page and helpful information for the marker on the facing page, such as symbol, gene name, synonyms, chromosome location, brief informative description of the morphology, and comments on marker reliability. A companion website with updated information, useful links, and additional data provided by the authors complements this extremely valuable resource.
Provides an opening chapter with a well-illustrated introduction to Drosophila morphology Features high-resolution illustrations, including those of the most common markers used by Drosophila researchers Contains brief, practical descriptions and tips for deciphering the phenotype Includes material relevant for beginners and the most experienced fly pushers

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One of the major challenges of modern biology and medicine consists in finding means to visualize biomolecules in their natural environment with the greatest level of accuracy, so as to gain insight into their properties and behaviour in a physiological and pathological setting. This has been achieved thanks to the design of novel imaging agents, in particular to fluorescent biosensors.

Fluorescence Biosensors comprise a large set of tools which are useful for fundamental purposes as well as for applications in biomedicine, drug discovery and biotechnology. These tools have been designed and engineered thanks to the combined efforts of chemists and biologists over the last decade, and developed hand in hand together with imaging technologies.

This volume will convey the many exciting developments the field of fluorescent biosensors and reporters has witnessed over the recent years, from concepts to applications, including chapters on the chemistry of fluorescent probes, on technologies for monitoring protein/protein interactions and technologies for imaging biosensors in cultured cells and in vivo. Other chapters are devoted to specific examples of genetically-encoded reporters, or to protein and peptide biosensors, together with examples illustrating their application to cellular and in vivo imaging, biomedical applications, drug discovery and high throughput screening.
Contributions from leading authorities Informs and updates on all the latest developments in the field

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The Second Edition of this best-selling introduction for practitioners uses new material and updates to describe the changing environment for project finance. Integrating recent developments in credit markets with revised insights into making project finance deals, the second edition offers a balanced view of project financing by combining legal, contractual, scheduling, and other subjects. Its emphasis on concepts and techniques makes it critical for those who want to succeed in financing large projects. With extensive cross-references and a comprehensive glossary, the Second Edition presents anew a guide to the principles and practical issues that can commonly cause difficulties in commercial and financial negotiations.
Provides a basic introduction to project finance and its relationship with other financing techniques Describes and explains: sources of project finance; typical commercial contracts (e.g., for construction of the project and sale of its product or services) and their effects on project-finance structures; project-finance risk assessment from the points of view of lenders, investors, and other project parties; how lenders and investors evaluate the risks and returns on a project; the role of the public sector in public-private partnerships and other privately-financed infrastructure projects; how all these issues are dealt with in the financing agreements