# data[].attributes.subtitle
Structure, Function, and Genetic Control

# data[].attributes.description
The Plasma Proteins: Structure, Function, and Genetic Control, Second Edition, Volume I is a systematic account of the structure, function, and genetic control of plasma proteins. Clinical relevance is introduced in terms of principles, with emphasis on human proteins. Animal proteins are also used as examples in some cases.

Comprised of nine chapters, this volume begins with a historical background on plasma proteins, along with their nomenclature, characterization, and genetic markers. The primary structure and three-dimensional conformation of plasma proteins are also considered. The discussion then turns to the chemical, physical, and biological properties of various plasma proteins such as serum albumin, lipoproteins, and immunoglobulins. Subsequent chapters deal with protease inhibitors in plasma; purification, physical properties, chemical composition, and molecular structure of transferrin; biosynthesis and metabolism of serum lipoproteins; and physical, chemical, and functional properties of the proteins of the complement system. The final chapter is devoted to ?2-microglobulin, with particular reference to its purification and physical properties; chemical composition and structure; physiological function, biosynthesis, and catabolism; and presence and function in cell membranes.

This monograph will be of interest to molecular biologists and biochemists.

# data[].attributes.description
Biochemistry: An Analysis of Global Change provides information pertinent to the chemistry of the surface of the Earth. This book presents the basics about the effect of life on the chemistry of the Earth.  Organized into two parts encompassing 14 chapters, this book begins with an overview of the connection between the elements that are significant to life. This text then describes how computer models are employed to help understand elemental cycling and ecosystem function. Other chapters consider how satellite technology is beneficial in understanding global biochemistry. This book discusses as well the essential role theta the Earth Observing System (EOS) will play in investigations of global ecology. The final chapter deals with the human effect on global biochemical cycles, with focus on controlling human population growth to maintain life and quality of life on Earth.  This book is a valuable resource for college-level and graduate students who are interested in global change.

# data[].attributes.description
Aperiodicity and Order, Volume 1: Introduction to Quasicrystals deals with various aperiodic types of order in quasicrystals as well as the basic physics of quasicrystalline order and materials. Questions about the nature of order and the order of nature are addressed.  This volume is comprised of six chapters; the first of which introduces the reader to icosahedral coordination in metallic crystals, with emphasis on the structural principles of metallic materials that are crystalline and may be expected to carry over to aperiodic materials. The discussion then turns to short- and long-range icosahedral orders in glass, crystals, and quasicrystals. The origins of icosahedral order are explained, and the physical properties of icosahedral materials are described. The chapters that follow focus on the metallurgy of quasicrystals, the crystallography of ideal icosahedral crystals, and stability and deformations in quasicrystalline solids. The book concludes with a discussion on symmetry, elasticity, and hydrodynamics in quasiperiodic structures. A pedagogical review of continuum elastic-hydrodynamic theory for quasicrystals and related structures is presented.  This book is intended primarily as an introduction for new students in the field and as a reference for active researchers.

# data[].attributes.description
Air PollutionPhysiological Effects focuses on the physiological effects of air pollution and reviews research findings concerning physiological responses to air pollutants such as oxidant gases, sulfur dioxide, carbon monoxide, and particulates. Topics range from cellular cytotoxicity and lung infections to carbon monoxide toxicity, deposition of aerosols to the respiratory airway, physiological effects of cotton dusts and lead dusts, and workers' exposure to dust at high altitude.  This book is organized in three sections and is comprised of 11 chapters. The discussion begins with an overview of cellular cytotoxicity and the biochemical basis of oxidative cell killing. The reader is methodically introduced to the effects of minute concentrations of pollutants on animal respiratory defenses, air pollution by sulfur products, and mechanisms of carbon monoxide toxicity. Consideration is also given to alterations in airway mechanics that occur with exposures to ozone, nitrogen dioxide, and sulfur dioxide, as well as the mechanisms that might be responsible for these changes in breathing mechanics. The rest of the book discusses both particulate (silica, diesel, cotton, and lead dusts) pollution and the special physiological problems posed by working at high altitudes in dusty environments.  This book will be useful not only to environmental health scientists but also to students and researchers in areas peripheral to environmental physiology.

# data[].attributes.name
Nucleosides, Nucleotides and their Biological Applications

# data[].attributes.description
Nucleosides, Nucleotides, and Their Biological Applications contains the proceedings of the Fifth International Round Table on Nucleosides, Nucleotides, and Their Biological Applications held at Research Triangle Park, North Carolina on October 20-22, 1982. Contributors focus on the biological applications of nucleosides and nucleotides, along with advances in synthetic chemistry. Topic range from fast-moving biochemical subjects such as the 2',5'-oligoadenylates and their relationship to interferons; adenosine and adenine nucleotide receptors; and nucleosides with selective antiviral action.  This volume is organized into 11 chapters and begins with an overview of nucleosides that are used as antiviral agents and their mechanism of action, including idoxuridine, vidarabine, and trifluridine. The discussion then shifts to the chemical and biological properties of nucleosides of purines and ring analogs; 2'-fluoroarabinosyl pyrimidines and purine-like C-nucleosides; and the potential of 2',5'-oligoadenylates as chemotherapeutic agents. The reader is also introduced to receptors for adenosine and adenine nucleotides; the function of pyrrolo[2,3-d]pyrimidine nucleosides in polynucleotides; and unusual nucleoside synthons and oligonucleotide synthesis. A chapter on the synthesis of versatile C-nucleoside precursors and certain C-nucleosides concludes the book.  This book will be of value to chemists, biologists, and those with an interest in nucleosides and nucleotides.

# data[].attributes.description
The Carbohydrates: Chemistry and Biochemistry, Second Edition, Volume IA deals with the chemical and biochemical aspects of carbohydrates such as monosaccharides, sugars, esters, halogen derivatives, phosphates, glycosides, glycosans, alditols, and cyclitols. Topics range from carbohydrate chemistry and stereochemistry to the synthesis of naturally occurring monosaccharides, mutarotations and actions of acids and bases, conformations of sugars, and reactivity of saccharide hydroxyl groups toward esterification.  This book consists of 15 chapters that explore the effects of ionizing radiations and autoxidation reactions, physical methods and methods of separation, nucleosides and antibiotics, and the biosynthesis of sugars and complex saccharides. The rapidly growing fields of glycolipids and glycoproteins are also discussed. In addition, the reader is introduced to halogen derivatives such as glycosyl halides and nonanomeric halides, along with the hydrolysis and synthesis of phosphates and other inorganic esters, determination of the structure of glycosides, and the physical and chemical properties of acyclic derivatives. The two final chapters cover the official nomenclature rules for carbohydrates and for enzymes having carbohydrates as substrates.  This book will be of interest to chemists and biochemists.

# data[].attributes.description
Plasma Polymerization aims to bridge the conceptual gap between the academic and practical approaches to plasma polymerization and highlights the significance of plasma polymerization in materials science and technology. The major topics covered are gas-phase kinetics, ionization of gases, fundamentals of polymerization, mechanism of polymer formation in plasma, competitive aspects of polymer formation and ablation, mechanism of polymer deposition, operational factors of plasma polymerization, and electrical properties of plasma polymers.  This book is comprised of 11 chapters and begins with a brief overview of plasma polymerization and its growing importance for the formation of entirely new kinds of materials. The discussion then shifts to a comparison between plasma-state polymerization and plasma-induced polymerization, between plasma polymerization and graft polymerization, and between plasma polymerization and radiation polymerization. The reader is also introduced to fundamental aspects of gas-phase reactions, paying particular attention to the classical kinetic theory of gas, as well as the mechanisms of formation of polymeric materials in plasma, competitive ablation and polymer formation in plasma, and polymer deposition in plasma polymerization. The operational parameters of plasma polymerization are described and a chapter devoted to the electrical properties of plasma-polymerized thin organic films concludes the book.  This book will be of interest to students and researchers of material science.

# data[].attributes.description
The Initiation of DNA Replication contains the proceedings of the 1981 ICN-UCLA Symposia on Structure and DNA-Protein Interactions of Replication Origins, held in Salt Lake City, Utah on March 8-13, 1981. The papers explore the initiation of DNA replication and address relevant topics such as whether there are specific protein recognition sites within an origin; how many proteins interact at an origin and whether they interact in a specific temporal sequence; or whether origins can be subdivided into distinct functional domains. The specific biochemical steps in DNA chain initiation and how they are catalyzed are also discussed.  This book is organized into six sections and comprised of 41 chapters. The discussion begins by analyzing the replication origin region of the Escherichia coli chromosome and the precise location of the region carrying autonomous replicating function. A genetic map of the replication and incompatibility regions of the resistance plasmids R100 and R1 is described, and several gene products produced in vivo or in vitro from the replication region are considered. The sections that follow focus on the DNA initiation determinants of bacteriophage M13 and of chimeric derivatives carrying foreign replication determinants; suppressor loci in E. coli; and enzymes and proteins involved in initiation of phage and bacterial chromosomes. The final chapters examine the origins of eukaryotic replication.  This book will be of interest to scientists, students, and researchers in fields ranging from microbiology and molecular biology to biochemistry, molecular genetics, and physiology.

# data[].attributes.description
Biology and Geology of Coral Reefs, Volume I: Geology 1 focuses on the evolution, reef types, geology, and structural and tectonic factors causing the development of coral reefs.   The selection first offers information on the coral reefs of the Caribbean and Indian Ocean, including evolution, physical environment, coral diversity, reef communities, reef types and zonation, and reef morphology and sea-level change. The manuscript then takes a look at the Bikini and Eniwetok Atolls in Marshall Islands; geomorphology and geology of coral reefs in French Polynesia; and the coral reefs of New Caledonia.   The publication examines the coral reefs of the New Guinea region and waters of the Great Barrier Reef province. Topics include climate, seasonal variations in temperature and salinity, and water masses in the Coral Sea and their effect on the Great Barrier Reef. The book also ponders on the geomorphology of Eastern Queensland in relation to the Great Barrier Reef; structural and tectonic factors influencing the development of coral reefs off Northeastern Queensland; and sediments of the Great Barrier Reef province.   The selection is a vital source of information for marine biologists and readers interested in the geology, evolution, physical environment, and diversity of coral reefs.

# data[].attributes.description
Enzymes as Targets for Drug Design is a collection of scientific discussions related to enzyme inhibitors that show the many facets of the drug discovery process from the basic sciences through clinical applications. Topics include the biogenesis of phosphatidylinositol glycosyl membrane proteins, structure and catalytic function of ADP-ribose polymerase (ADPRT), and modulation of the dopaminergic system in cardiovascular therapeutics. The therapeutic utility of selected enzyme-activated irreversible inhibitors, the role of proteinases in the fibrosis of systemic sclerosis, and therapeutic opportunities in eicosanoid biosynthesis are also discussed.

This book consists of 18 chapters and begins with examples of enzymes whose activities have recently been elucidated, or for which newer insights have been gleaned, but which do not yet have selective or potent inhibitors. The second part provides examples of enzymes where inhibitors have been identified but it is still not clear whether or not such an enzymatic blockade will be therapeutically beneficial. The final section describes clinical studies of newer, and not so new, enzyme inhibitors that are clearly of therapeutic importance. The therapeutic activity of monoamine oxidase inhibitors and the associated clinical issues are considered.

This book is intended for clinicians as well as basic scientists in biochemistry, chemistry, pharmacology, and cell biology.

# data[].attributes.description
Nutrition and Aging is a collection of papers presented at the Fifth Bristol-Myers Symposium on Nutrition Research, held in Boston, Massachusetts from October 31 to November 1, 1985. Contributors discuss the significant influence of nutrition on aging, and specifically the role of nutrition in preventing and limiting the physical, mental, and emotional problems associated with the aging process.  This book reviews findings that include the effects of the aging process on the body's physiological functions and the effects of nutrient intake on organ function. Consideration is also given to the gap between the documented nutrient intake and nutrient needs of the elderly as it may influence the aging process. The first chapter is a brief overview of the variety of problems that have to be resolved in determining the role of nutrition in aging. The discussion then turns to the relationship of nutrition to changes in physiological function during the aging process, along with factors that influence the nutrient needs of the elderly. The final chapters focus on the impact of nutrition on the etiology of age-related degenerative diseases.  This book will be of interest to scientists as well as students and researchers engaged in nutrition research and its growing importance to the prevention and treatment of disease.

# data[].attributes.description
A Textbook of Physical Chemistry, Second Edition serves as an introductory text to physical chemistry. Topics covered range from wave mechanics and chemical bonding to molecular spectroscopy and photochemistry; ideal and nonideal gases; the three laws of thermodynamics; thermochemistry; and solutions of nonelectrolytes. The kinetics of gas-phase reactions; colloids and macromolecules; and nuclear chemistry and radiochemistry are also discussed.  This edition is comprised of 22 chapters; the first of which introduces the reader to the behavior of ideal and nonideal gases, with particular emphasis on the van der Waals equation. The discussion then turns to the kinetic molecular theory of gases and the application of the Boltzmann principle to the treatment of molar polarization; dipole and magnetic moments; the phenomenology of light absorption; and classical and statistical thermodynamics. The chapters that follow focus on the traditional sequence of chemical and phase equilibria, electrochemistry, and chemical kinetics in gas phase and solution phase. This book also considers wave mechanics and its applications; molecular spectroscopy and photochemistry; and the excited state, and then concludes with an analysis of crystal structure, colloid and polymer chemistry, and radio and nuclear chemistry.  This reference material is intended primarily as an introductory text for students of physical chemistry.

# data[].attributes.name
The Neuroendocrine Aspects of Reproduction

# data[].attributes.description
Neuroendocrine Aspects of Reproduction contains the proceedings of the Oregon Regional Primate Research Center's Second Symposium on Primate Reproductive Biology held in Beaverton, Oregon, on October 8-9, 1982. The symposium provided a forum for discussing the neuroendocrinology of reproduction in primates and tackled topics ranging from delayed puberty as a factor in human evolution to gonadotropin-releasing hormone neurons and pathways in the primate hypothalamus and forebrain.  Comprised of 18 chapters, this book begins with an overview of some basic neuroendocrine mechanisms that influence reproductive processes, followed by a discussion on control of the onset of puberty. Control of ovulation in the rhesus macaque is considered, along with hypothalamic regulation of gonadotropin secretion in women. The next section deals with reproductive cyclicity in female primates and the extent to which the central nervous system participates in the control of such cyclicity. Subsequent chapters explore the biological basis for the contraceptive effects of breastfeeding; the effects of hyperprolactinemia on reproductive function in humans; and neuroendocrine changes during menopausal flushes.   This monograph will be of interest to students, practitioners, and researchers in the fields of reproductive biology, neuroendocrinology, and physiology.

# data[].attributes.description
Trace Analysis by Mass Spectrometry deals with trace analysis of solids and liquids by mass spectrometric techniques. Topics include the physics and techniques of electrical discharge ion sources, transmission of ions through double focusing mass spectrometers, and detection and measurement of ions by ion-sensitive plates. The ion sources used are principally electrical discharge type sources.   This book is comprised of 14 chapters. The first several chapters focus on the basic physics of electrical discharge ion sources, double focusing mass spectrometry, and the measurement of arrays of mass resolved ion beams by electrical detection methods and with ion sensitive emulsions. The discussion then shifts to the problem of obtaining the chemical composition of the recorded mass resolved ion sample and relating this composition to that of the original sample. The chapters that follow describe specific techniques for analyzing special samples such as insulators, powders, microsamples, biological materials, reactive and low melting point substances, radioactive materials, and gases in solids. The remaining chapters include the use of laser ion sources in the analysis of solids and the analysis of surfaces particularly with sputter ion sources.  This book will be of interest to students and practitioners of physics and chemistry.

# data[].attributes.description
Current Research in Protein Chemistry: Techniques, Structure, and Function reviews new techniques and methods for determining the structure and function of proteins. Topics covered include protein folding and stability, chimeric proteins, amino acid and peptide analysis, mass spectrometric methods, and protein sequencing techniques.  This book is divided into six sections comprised of 55 chapters. The discussion begins with a description of microwave irradiation that uses Teflon-Pyrex tubes for protein hydrolysis, followed by the application of high performance capillary electrophoresis to the analysis of amino acids. The sections that follow explore mass spectrometry, protein sequencing, and capillary electrophoresis as well as protein stability, chimeric proteins and enzyme modifications, and protein structure prediction. Chapters focus on the crystal structure of human interleukin-1a, the acid-denatured states of proteins, solubility of recombinant proteins expressed in Escherichia coli, and catalysis by chimeric proteins.  This book will be of value to students and researchers interested in protein chemistry.

# data[].attributes.description
Methods in Plant Biochemistry, Volume 1: Plant Phenolics reviews current knowledge about techniques used in the analysis of the biochemistry of plant polyphenols and their importance in the agricultural and food industries. It looks at the application of these techniques in the fractionation of cellular constituents, isolation of enzymes, electrophoretic separation of nucleic acids and proteins, and chromatographic identification of the intermediates and products of cellular metabolism.     Organized into 15 chapters, this book opens with an overview of the general procedures and measurement of total phenolics, from detecting phenolic substances in crude plant extracts to determining which classes they belong to and the quantitative estimation of total phenol. The reader is introduced to the chemistry, structural variation, function, and distribution of each class of plant phenolics and, in a few cases where this is practicable, detailed listings of known derivatives are given. Most chapters focus on chromatographic separations and high performance liquid chromatography (HPLC), along with thin layer and paper Rf values with HPLC retention times and NMR spectroscopy. The book also outlines the procedures for the extraction, isolation, separation, and characterization of different classes of phenolic compounds, ranging from phenols and phenolic acids to phenylpropanoids, lignins, stilbenes and phenanthrenes, flavones and flavonols, chalcones and aurones, flavanoids, anthocyanins, biflavanoids, tannins, isoflavanoids, quinones, xanthones, and lichen substances.     The book is a valuable resource for students, biochemists, and researchers in the plant sciences.

# data[].attributes.name
NK Cells and Other Natural Effector Cells

# data[].attributes.description
NK Cells and Other Natural Effector Cells reviews the state of knowledge on NK cells and other natural effector mechanisms. The coverage of immune effector systems ranges from basic studies on their nature, regulation, and mechanisms of action to important practical issues such as their role in host resistance, their modulation by therapeutic intervention, and alterations of their activity in disease.  The book is organized into 12 parts. Parts I and II examine the characteristics of NK cells and other natural effector cells, respectively. Part III focuses on the cell lineage of NK and related effector cells, providing evidence for or against T cell lineage, for or against macrophage lineage, and for or against other or separate lineage. Part IV deals with the genetics of natural resistance in the mouse and rat. Part V presents studies on the regulation of cytotoxic activity. Part VI examines the specificity of natural effector cells, covering the nature of target cell structures and the nature of recognition receptors in effector cells. Part VII discusses the cytotoxicity by cultured lymphoid cells while Part VIII turns to the mechanisms of cytotoxicity. Part IX deals with natural cell-mediated reactivity against primary tumor cells and against non-tumor targets. Part X examines NK cell tumors or the presence of NK cells at the site of tumor growth. Part XI presents clinical studies with natural effector cells. Part XII provides evidence for in vivo reactivity of natural effector cells.

# data[].attributes.name
Catalytic Hydrogenation in Organic Syntheses

# data[].attributes.description
Catalytic Hydrogenation in Organic Syntheses focuses on the process of catalytic hydrogenation in organic synthesis. This book gives the reader easy access to catalytic history, to show what can be done and how to do it. A variety of working generalities and common sense guides are given as aids in selecting catalytic metal, catalyst support, concentration of metal and catalyst, solvent, and reaction conditions. All manner of hydrogenation catalysts are considered and mechanisms of hydrogenation are presented at a level that is useful to the synthetic organic chemist.  This volume is comprised of 15 chapters and begins with an overview of catalytic hydrogenation and heterogeneous hydrogenation catalysts, along with hydrogenation reactors and reaction conditions. The discussion then shifts to the hydrogenation of compounds such as acetylenes, olefins, aldehydes, ketones, nitriles, oximes, acids, esters, lactones, anhydrides, and nitro compounds as well as carbocyclic aromatics and heterocyclic compounds. The reader is also introduced to reductive alkylation, catalytic dehydrohalogenation, and hydrogenolysis of small rings. A chapter on miscellaneous hydrogenolyses concludes the book.  This book will be of interest to organic chemists working in the field of catalytic hydrogenation.

# data[].attributes.name
Genetics and Biotechnology of Bacilli, Volume 2

# data[].attributes.description
Genetics and Biotechnology of Bacilli, Volume 2 is a collection of papers from the "Fourth International Conference on Bacilli" held in California on June 21-24, 1987. One paper reviews the results of cloning and characterization of genes for secreted enzyme and of genes that control the expression of secreted enzymes in relation with other prokaryotic regulatory systems. Other papers tackle the regulation of gene expression during sporulation, the sigma factors, bacterial toxins, and antibiotic resistance genes. One paper reports that three genes responsible for the code for peptides found in BT cuboidal crystals have been successfully cloned. The three codes have different toxic characteristics in relation to tobacco hornworm larvae or mosquito larvae. Other papers examine replication. Such examination pertains to the two levels of control on the chromosome involved in DNA replication, or to the possible functional importance that several membranes associated DNA subcomplexes can have in Bacillus subtilis, where one of these appear to control initiation. Other papers discus secretion and extracellular enzymes, as well as, the different genetic systems and methods. This collection can prove beneficial for biochemists, micro-biologists, cellular researchers, and academicians involved in the study of cellular biology, microchemistry, or toxicology.

# data[].attributes.description
Environmental Toxicology of Pesticides provides an overview of the state of knowledge in the major pesticidal subject areas and describes the efforts and approaches underway in solving or understanding these problems. The book emerged from the United States-Japan seminar on ""Environmental Toxicology of Pesticides"" held in Oiso, Japan, in October 1971. The purpose of the seminar was to discuss and exchange ideas and technology on the problems associated with pesticidal contamination in these two countries.   The book is organized into eight parts. Part I reviews pesticide use and contamination levels in Japan, the United States, and Britain. Part II examines the environmental impact of mercury. Part III presents studies on chlorinated hydrocarbon pesticides. Part IV examines the effects of fungicides, herbicides, organophosphates, and carbamates. Part V deals with the microbial degradation of pesticides. Part VI examines the photodecomposition of pesticides. Part VII investigates the biological effects of pesticides on wildlife. Part VIII deals with the development of new pesticides.