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The Structural Basis of Membrane Function

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The Structural Basis of Membrane Function is a documentation of an international symposium of the same title. This book serves as a collection of the significant articles pertaining to the field of membrane research. It is composed of seven parts, where the first and last parts are articles contributed by scientific authorities.   The book generally discusses the membrane research and this studys relevance to the society. Then, the book specifically looks into membrane features, including its structure, processes in it, functions, and types. Some of the specific topics included in the discussion of each part are phospholipases and monolayers used in studies of membrane structure; molecular aspects of active transport; and electron-transfer in energy-transducing membranes. The book also explains the two functions in common of biological membranes; synaptic receptor proteins; and liver microsomal membranes.   The scope of this book is broad and helpful to many fields of scienec. It will be of great benefit to students, teachers, scientists, and researchers in the field of biochemistry, biology, molecular biology, chemistry, pharmacology, and cellular biology among others.

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Dynamics of Gas-Surface Scattering deals with the dynamics of scattering as inferred from known properties of gases and solids. This book discusses measurements of spatial distributions of scattered atomic and molecular streams, and of the energy and momentum which gas particles exchange at solid surfaces. It also considers two regimes of scattering, both of which are associated with a lower range of incident gas energies: the thermal and structure scattering regimes.  Comprised of 10 chapters, this book opens with a brief historical overview of the early experiments that investigated the dynamics of scattering of gases by surfaces. The discussion then turns to some elements of the kinetic theory of gases; intermodular potentials and interaction regimes; and classical-mechanical lattice models used in gas-surface scattering theory. The applications of molecular beams to the study of gas-surface scattering phenomena are also described. The remaining chapters focus on experiments and theories on scattering of molecular streams by surfaces of solids, with emphasis on thermal and structure regimes of inelastic scattering; quantum theory of gas-surface scattering; and quantum mechanical scattering phenomena. This text concludes with an analysis of energy exchange processes that may occur when a solid surface is completely immersed in a still gas.  This monograph will be a valuable resource for students and practitioners of physics, chemistry, and applied mathematics.

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Development and Evolution of Brain Size: Behavioral Implications contains the proceedings of a symposium entitled ""Development and Evolution of Brain Size: Behavioral Implications,"" held at William Paterson College in Wayne, New Jersey, in April 1978. The papers explore the relationship between evolution and development and its implications for brain size and behavior.   This book is comprised of 18 chapters and begins with an overview of the brain-behavior relationship, with emphasis on the importance of brain size for behavior; the effects of genetic selection for brain size on brain substructures and behavior; and whether genetic and environmental manipulations of brain size have similar consequences. The next two chapters explain evolutionary theory and the evolution of the human brain as well as diversity in brain size. A general model for brain evolution that offers some synthetic possibilities for approaching the questions of brain evolution, size, allometry, and reorganization is then described. The correlation between cerebral indices and behavioral differences is also discussed, along with biochemical correlates of selective breeding for brain size. The results of an experiment that assessed the effects of early undernutrition on brain and behavior of developing mice are presented.  This monograph should be of interest to students and practitioners in a wide range of disciplines, including evolutionary biology and clinical psychology.

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High Temperature Vapors: Science and Technology focuses on the relationship of the basic science of high-temperature vapors to some areas of discernible practical importance in modern science and technology. The major high-temperature problem areas selected for discussion include chemical vapor transport and deposition; the vapor phase aspects of corrosion, combustion, and energy systems; and extraterrestrial high-temperature species.  This book is comprised of seven chapters and begins with an introduction to the nature of the high-temperature vapor state, the scope and literature of high-temperature vapor-phase chemistry, and the role of high-temperature vapors in materials science. The discussion then turns to gas-solid reactions with vapor products; chemical vapor transport and deposition; vapor-phase aspects of corrosion at high temperature; and flames and combustion. High-temperature vapor-phase processes associated with gas turbine systems are also considered. The final chapter is devoted to the chemistry of high-temperature species in space.  This monograph should serve as a valuable reference for undergraduate and graduate students, as well as scientists in fields such as chemistry, physics, materials science, and metallurgy.

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Experimental Neutron Resonance Spectroscopy deals with the experimental technique of neutron resonance spectroscopy. Pulsed accelerator time-of-flight spectrometers and gamma rays from neutron capture in resonances are discussed. Total neutron cross section measurements are presented, along with neutron scattering and capture cross-section measurements and measurements on fissile nuclides.   This book is comprised of five chapters and begins with an introduction to pulsed accelerator time-of-flight spectrometers with moderated continued neutron spectra, together with the pulsed Van De Graaff. Experimental techniques used for neutron cross section measurements, including detectors and data acquisition equipment, are then outlined. Scattering measurements and capture measurements as well as gamma-ray spectra from the capture of neutrons in resonances are considered. The final chapter focuses on the detailed and varied experiments that have been performed on the complicated fission process, together with the parameters of the resonances of the fissile nuclides.  This monograph will be a useful resource for spectroscopists and physicists.

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Aspects of Sponge Biology is the result of a symposium about sponge biology held in Albany, New York in May 1975. The symposium not only presents investigations, but also problem areas in the field of sponge biology. This book therefore shows that sponges are a very challenging and untouched subject area for future studies.   This book is divided into three major parts, wherein the first part introduces and discusses sponge biology. The introduction and discussion include sponge biology principles, perspectives, and problems. The next two parts discuss cell and development biology, taxonomy, and ecology. Part 2 deals with several topics of the cellular aspect, including an analysis of reproduction in sponge populations and cytochemical studies of connective tissues in sponges. This part also looks into the cytological abnormalities in various normal and transformed cell lines. Part 3 describes the different types of sponge in their various habitats. Sponge feeding mechanisms, ecological factors controlling sponge distribution, and zoogeography of Brazilian marine Demospongiae are also discussed in this part.  This book will be of important value to biology students and teachers. Specialists including zoologists, ecologists, comparative physiologists, and biologists will also benefit from this book.

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ISDN Design: A Practical Approach is an easy-to-understand reference for ISDN and covers topics relating to both theoretical and practical issues concerning ISDN design, including the ISDN terminal and the ISDN exchange. Software programs for ISDN applications are considered, and many design examples are given throughout the text.  This book is comprised of nine chapters and begins with a brief discussion of the need for ISDN technology, both from the point of view of telephone design and from the perspective of PBX design. A refresher of basic concepts needed to understand the subject follows. This includes topics ranging from the theoretical side of data transmission to the requirements of ISDN circuit layout. After this foundation is laid, an overview of the relevant international and national standards that exist in the ISDN telephone world is given. Subsequent chapters deal with ISDN terminal equipment design; the primary access side of the network; software issues raised by ISDN, with emphasis on the effects on system and hardware design; and testing of ISDN designs. The final chapter brings together all of the salient issues facing the ISDN designer and describes an actual ISDN design.  This monograph will be a useful resource for both newcomers in design engineering and experienced design engineers.

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Hazard Assessment of Chemicals: Current Developments, Volume 1 is a comprehensive and authoritative account of major developments in hazard assessment of chemicals. In addition to subject reviews, this volume contains case histories of topical chemicals and/or chemical classes in order to show examples of the applications of available methods and approaches for evaluating chemicals. Primary and secondary sources of information on chemicals are considered, along with the environmental and health hazards associated with chemicals.  Comprised of 10 chapters, this volume begins with an assessment of information sources on toxic substances, followed by a discussion on pre-concentration of trace metals from aquatic environmental samples. Subsequent chapters focus on the reproductive toxicology of aquatic contaminants; partition coefficient and water solubility in environmental chemistry; in vitro metabolism and activation of chemical carcinogens; and modeling of toxic spills into waterways. Estimation of exposure to hazardous chemicals is also described, along with structure-activity relationships in hazard assessment. The final chapter presents a case study of azaarenes, with emphasis on their sources, distribution, environmental impact, and health effects.  This book will be of interest to toxicologists, chemists, and environmental and public health officials.

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Bacterial Energetics deals with bacterial energetics and the molecular basis of how ions move between and within energy-transducing molecules. Topics covered range from respiration-driven proton pumps and primary sodium pumps to light-driven primary ionic pumps, bacterial transport ATPases, and bacterial photosynthesis. Sodium-coupled cotransport and ion-exchange systems in prokaryotes are also considered.  This volume is comprised of 17 chapters and begins with an analysis of the pumps and processes that establish electrochemical ion gradients across bacterial membranes, followed by a discussion on the major types of bioenergetic work that utilize these gradients. The energetics of periplasmic transport systems, chemolithotrophs, methanogens, and protein insertion and translocation into or across membranes are also examined, along with bioenergetics in extreme environments such as high-pressure and high-temperature environments; energetic problems of bacterial fermentations; energetics of bacterial motility; and energetics of the bacterial phosphotransferase system in sugar transport and the regulation of carbon metabolism.    This book should be of interest to molecular biologists and biochemists.

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Molecular Basis of Bacterial Pathogenesis

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Molecular Basis of Bacterial Pathogenesis focuses on the molecular mechanism of disease associated with bacterial pathogens. Topics covered include the population genetics of bacterial pathogenesis; environmental modulation of gene expression in gram-negative pathogens; and bacterial invasion and intracellular growth. Bacterial toxins are also discussed.  This volume is comprised of 20 chapters and begins with an overview of pathogenesis, paying particular attention to common elements and genetic mechanisms of regulation. The discovery that many bacterial pathogens are clonal, with individual clones often having a greater virulence than others, is then considered. The next section deals with the regulation of synthesis of surface components and their role in colonization of the host and/or evasion of the host immune defense systems; antigenic variation and its role in evasion of the host immune response; and the role of iron acquisition systems in the colonization of the host. Subsequent chapters explore the invasion and intracellular growth of facultative and obligate intracellular parasites. The last section is devoted to studies on the role of bacterial toxic products in pathogenesis. Bacterial lipopolysaccharides (endotoxins) and exotoxins are described.  This book should be of interest to molecular biologists, physiologists, clinical specialists, pathologists, and geneticists.

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Chromosome Microdissection and Cloning: A Practical Guide is a straightforward guide to chromosome microdissection and cloning. It presents an overview of the procedures and briefly reviews a few areas of research in which these techniques are applied. Topics range from preparation of chromosomes for microdissection to molecular cloning of microdissected chromosomal DNA. Methods of chromosome microdissection, including video microscope method and oil chamber method, are described.  Comprised of five chapters, this book begins with an overview of the structure and organization of chromosomes, followed by a description of methods for preparing and preserving chromosomal DNA in a manner that is useful for cloning and direct analysis. Microdissection of metaphase chromosomes and isolation of fragments can be accomplished in one of the three ways described in the next chapter: by microdissection using an upright microscope and glass capillaries in an oil chamber; by laser microbeam; and with the use of an inverted microscope equipped with a video camera and high magnification-high resolution lenses. A step-by-step guide to these techniques and solutions for common problems are given following each method. Protocols for cloning and identifying genetic sequences from defined chromosome regions, particularly using the polymerase chain reaction, are also discussed. The final chapter focuses on applications of chromosome microdissection, such as cloning of disease-specific genes and generating "sequence tagged sites" to be used in large DNA sequencing projects.  This monograph will be particularly helpful to investigators setting up microdissection systems de novo.

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Cell Biology A Comprehensive Treatise V3

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Gene Expression: The Production of RNA's

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Cell Biology, A Comprehensive Treatise, Volume 3: Gene Expression: The Production of RNAs mainly discusses the molecular and cytological bases of gene expression. The coverage begins with the concepts of organization of DNA and gene sequences in chromosomes, as an introduction to a more detailed coverage of gene expression.  The book opens with a general discussion on the organization of DNA sequences in chromosomes. This chapter includes different methods of analyzing DNA sequences. As the book progresses, it looks upon the details on gene reiteration and amplification up to the transcription of prokaryotes and eukaryotes. It includes the ways of regulating transcription.  The following chapters deal mostly with the structure and activity of genes up to the different virus strains in both RNA and DNA. The cytoplasmic and environmental impact on gene expression is also discussed. Chapter 8 generally tackles the DNA conformation and template function. The succeeding chapters focus on the transfer and ribosomal RNA as a result of maturation events; the processing of hnRNA and its relation to mRNA; and recombinant DNA procedures.  The book closes with the directory of the different classes of cellular RNAs. This book will be helpful to many graduate students, teachers, scientists, and researchers in need of information regarding cell biology.

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Biological Effects of Radiation, Second Edition aims to present an organized survey of the various experiments wherein living materials have been exposed to ionizing and exciting types of radiations. However, this book focuses on the effects of radiation to lower organisms, as these have received less attention. It tells how small amount of energy can damage submicroscopic structure and ultimately alter the appearance and abilities of such organisms.  Divided into five parts, this book starts off with two introductory chapters in the first part. It explains the effects of radiation. Then, other parts of the book focus on the impact of radiation from cellular to organ level. How the lower organisms response is then discussed. Lastly, the book explains the interrelations between organisms in contaminated areas. Same with the first edition, emphasis is given on the consequences of mutations, as a whole chapter is devoted to this topic. Furthermore, this book covers discoveries from experiments with cultured cells.  This book is a good text-reference for students and professionals. Also, it can be of great help to scientists, researchers, and specialists involved in the biological response to radiation.

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The Peptides Analysis, Synthesis, Biology

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Modern Techniques of Conformational Structural, and Configurational Analysis

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The Peptides: Analysis, Synthesis, Biology: Volume 4: Modern Techniques of Conformational, Structural, and Configurational Analysis is an open-ended treatise that provides comprehensive and critical reviews of important developments in all areas of peptide research including analysis, synthesis, and biology. X-ray structure studies, amino acid analysis, and chiroptical analysis of configuration are discussed, along with solid-phase sequencing and ultramicroanalysis with the aid of fluorescence.  This volume is comprised of six chapters and begins with an account of crystal structure analysis on molecules containing 2-12 peptide units, focusing on the variety of intramolecular hydrogen bonds, cis peptide units, and multiple conformation. Conformational changes upon complexation with metal ions are considered, together with the inclusion of solvents as integral parts of a molecular structure. The following chapters explore the conformations of insulin, glucagon, pancreatic polypeptide and related molecules, as well as the molecular biology of these hormones based on crystal structures; the usefulness of chiroptical techniques for determining the absolute configuration of amino acids and small peptides; and ultramicroanalysis of peptides and proteins by high performance liquid chromatography and fluorescence detection. The final chapter looks at the status and future potential of solid-phase sequencing.  This book is intended as a reference for specialists, a guide for the novice, and a forum for investigators concerned with research on peptides and proteins.

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The Bacteria: Volume IX: Antibiotic-Producing Streptomyces explores how Streptomyces, including actinomycetes, produce a variety of antibiotics such as aminocyclitols, ansamycins, macrolides, and tetracyclines. Topics covered range from physiology and fermentation to genetic recombination and chromosome mapping in Streptomyces, biomodification of antibiotics by Streptomyces, and biosynthesis of tylosin and erythromycin. The genome structure and evolution of Streptomyces are also discussed.   This volume is comprised of 10 chapters and begins with a discussion on the taxonomy of Streptomyces based on morphology, physiological characteristics, the composition of cell constituents such as cell walls, and the presence of characteristic lipids, sugars, and quinones. The discussion then turns to the intraspecific and interspecific recombination in Streptomyces; pathways of DNA repair and mutagenesis in Streptomyces fradiae; strategies for isolation of improved Streptomyces mutants for antibiotic production; and derivation of DNA cloning vectors from Streptomyces phages. The biology and use of Streptomyces plasmids as cloning vectors are also described. The final chapter is devoted to major structural classes of antibiotics produced by Streptomyces, including anthracyclines and other quinones, -lactams, macrolides, nucleosides, peptides, polyenes, polyether antibiotics, and tetracyclines.  This book will be of value to microbiologists, bacteriologists, biochemists, and biologists.

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Developmental NeuroPsychobiology reviews a variety of topics related to developmental neuropsychobiology, a discipline that encompasses developmental neuroscience and developmental psychobiology. This book discusses embryonic mechanisms and embryogenesis as well as sexual differentiation of the brain, synaptic plasticity, and parent-offspring relationships. The development of olfactory control over behavior is also discussed.  This book is comprised of 16 chapters and begins with an analysis of intrinsic mechanisms, including those underlying expression of pattern information at the cellular level and pattern formation in the vertebrate visual system. The next chapters also deal with pattern, but at a higher order, focusing upon the implications of the establishment of systems and how the sequences whereby these systems become established are manifested in the development of behavior. The morphogenetic role of neurotransmitters in embryonic development is also considered, along with structural and functional sexual dimorphisms in the brain and how steroid hormones alter brain organization. The final chapter evaluates previous models of the forces driving parent-offspring relations and offers an alternative view in which both infant-infant interactions and offspring-parent interactions result in mutually beneficial outcomes.  This monograph is intended for advanced workers in the biological and/or psychological sciences.

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Computer Image Processing and Recognition

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Computer Image Processing and Recognition

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Principles of Chemical Kinetics is devoted to the principles and applications of chemical kinetics. The phenomenology and commonly used theories of chemical kinetics are presented in a critical manner, with particular emphasis on collision dynamics. How and what mechanistic information can be obtained from various experimental approaches is stressed throughout this book.  Comprised of nine chapters, this text opens with an overview of reaction rates and their empirical analysis, along with theories of chemical kinetics. The following chapters consider reactions and unimolecular decompositions in the gas phase; chemical reactions in molecular beams; and energy transfer and partitioning in chemical reactions. Kinetics in liquid solutions and fast reactions in liquids are also described. The final chapter looks at the kinetics of enzymes, with particular reference to steady state and transient state kinetics, the pH and temperature dependence of kinetic parameters, and the mechanism underlying enzymatic action.  This monograph is intended for students with a general college background in chemistry, physics, and mathematics, and with a typical undergraduate course in physical chemistry.

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Electron Microscopy of Plant Cells serves as manual or reference of major modern techniques used to prepare plant material for transmission and scanning electron microscopy. There have been other books that generally discuss electron microscope methodology. This book focuses on problem areas encountered through the presence of tough cell walls and large central vacuole. It details preparative techniques for botanical specimens.  Each of the nine chapters of this book covers the basic principles, useful applications, and reliable procedures used on the method of electron microscopy. Other topics discussed in each chapter include the general preparation and straining of thin sections, quantitative morphological analysis, and enzyme cytochemistry. This book also explains the immunogold labelling, rapid-freezing methods, and ambient- and low-temperature scanning electron microscopy among others.  This book will be invaluable to general scientists, biologists, botanists, and students specializing in plant anatomy.

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Optical Radiation Measurements, Volume 1: Radiometry is an introduction to the measurement of optical radiant energy, with emphasis on the principles and generally applicable methods of radiometry. Topics range from basic concepts of radiant energy and its transfer to the calibration of instrumentation. Blackbody radiation and sources of radiation are also discussed, along with detectors and spectral analyzers.  Comprised of 10 chapters, this volume begins with an overview of the basic concepts and characteristics of radiometry as well as its applications such as photometry, photography, television, and vision research. The next chapters describe basic concepts such as radiation laws, terminology, and the transfer of radiant energy. The emphasis in these early chapters is on fundamentals. The major components of radiometric systems are then considered. The final three chapters focus on representative techniques, with particular reference to measurements of radiant power and radiant energy; reflectance, transmittance, and absorptance; and standards and calibration.   This book is written for students, practitioners, and researchers in physics.