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Arsenic abatement from groundwater in locations with a central water distribution system is relatively simple. The real challenge is selecting the most effective and affordable treatment and scale up option for locations which lack the appropriate infrastructure. Groundwater Arsenic Remediation: Treatment Technology and Scale UP provides the latest breakthrough groundwater treatment technologies and modeling and simulation methods for project scale up and eventually field deployment in locations which lack the proper central water distribution system to ensure arsenic free groundwater.
Covers the different removal methods, such as chemical, adsorption, separation by membranes, and membrane distillation Includes the state-of-the-art modeling & simulation methods for optimization and field deployment Provides economic and comparative analysis of each arsenic treatment technology

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Neuroimmune Signaling in Drug Actions and Addictions

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This well-established international series examines major areas of basic and clinical research within neuroscience, as well as emerging and promising subfields. This volume concentrates on Neuroimmune Signaling in Drug Actions and Addictions.
This book looks at neuroimmune signaling in drug actions and addictions in the light of the newest scholarly discoveries and insights

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Changhai Cui, David Shurtleff, R. Adron Harris

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A giant in the field and at times a polarizing figure, F. Albert Cottons contributions to inorganic chemistry and the area of transitions metals are substantial and undeniable. In his own words, My Life in the Golden Age of Chemistry: More Fun than Fun describes the late chemists early life and college years in Philadelphia, his graduate training and research contributions at Harvard with Geoffrey Wilkinson, and his academic career from becoming the youngest ever full professor at MIT (aged 31) to his extensive time at Texas A&M.; Professor Cottons autobiography offers his unique perspective on the advances he and his contemporaries achieved through one of the most prolific times in modern inorganic chemistry, in research on the then-emerging field of organometallic chemistry, metallocenes, multiple bonding between transition metal atoms, NMR and ESR spectroscopy, hapticity, and more. Working during a time of generous government funding of science and strong sponsorship for good research, Professor Cottons experience and observations provide insight into this prolific and exciting period of chemistry.
Offers personal and often wry perspective from this prominent chemist and recipient of some of sciences highest honors: the U.S. National Medal of Science (1982), the Priestley Medal (the American Chemical Society's highest recognition, 1998), membership in the U. S. National Academy of Sciences and corresponding international bodies, and 29 honorary doctorates Details the background behind the development and emergence of groundbreaking research in organometallic chemistry and transition metals Provides beautifully-written and engaging insight into a "Golden Age of Chemistry" and the work of historically renowned chemists

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Introduction to Actuarial and Financial Mathematical Methods

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This self-contained module for independent study covers the subjects most often needed by non-mathematics graduates, such as fundamental calculus, linear algebra, probability, and basic numerical methods. The easily-understandable text of Introduction to Actuarial and Mathematical Methods features examples, motivations, and lots of practice from a large number of end-of-chapter questions. For readers with diverse backgrounds entering programs of the Institute and Faculty of Actuaries, the Society of Actuaries, and the CFA Institute, Introduction to Actuarial and Mathematical Methods can provide a consistency of mathematical knowledge from the outset.
Presents a self-study mathematics refresher course for the first two years of an actuarial program Features examples, motivations, and practice problems from a large number of end-of-chapter questions designed to promote independent thinking and the application of mathematical ideas Practitioner friendly rather than academic Ideal for self-study and as a reference source for readers with diverse backgrounds entering programs of the Institute and Faculty of Actuaries, the Society of Actuaries, and the CFA Institute

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Pain is the number one reason that people seek medical attention but pain is still under- and poorly-treated world-wide. The purpose of this book is to give an up to date picture of what causes pain, how pain becomes chronic and what pharmacological targets might be manipulated to alleviate acute and chronic pain. The book will cover a wide array of topics from gene polymorphisms to voltage-gated ion channels moving from cellular biology to whole animal physiology.
Written by future leaders in the pain field Covers a wide range of targets Contains provocative ideas about the future direction of the pain field.

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Catalysis by Materials with Well-Defined Structures

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Catalysis by Materials with Well-Defined Structures examines the latest developments in the use of model systems in fundamental catalytic science. A team of prominent experts provides authoritative, first-hand information, helping readers better understand heterogeneous catalysis by utilizing model catalysts based on uniformly nanostructured materials.

The text addresses topics and issues related to material synthesis, characterization, catalytic reactions, surface chemistry, mechanism, and theoretical modeling, and features a comprehensive review of recent advances in catalytic studies on nanomaterials with well-defined structures, including nanoshaped metals and metal oxides, nanoclusters, and single sites in the areas of heterogeneous thermal catalysis, photocatalysis, and electrocatalysis.

Users will find this book to be an invaluable, authoritative source of information for both the surface scientist and the catalysis practitioner
Outlines the importance of nanomaterials and their potential as catalysts Provides detailed information on synthesis and characterization of nanomaterials with well-defined structures, relating surface activity to catalytic activity Details how to establish the structure-catalysis relationship and how to reveal the surface chemistry and surface structure of catalysts Offers examples on various in situ characterization instrumental techniques Includes in-depth theoretical modeling utilizing advanced Density Functional Theory (DFT) methods

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Seaweed Sustainability: Food and Non-Food Applications is the only evidence-based resource that offers an abundance of information on the applications of seaweed as a solution to meet an increasing global demand for sustainable food source.

The book uncovers seaweed potential and describes the various sources of seaweed, the role of seaweeds as a sustainable source for human food and animal feeds, and the role of seaweed farming for sustainability. In addition to harvesting and processing information, the book discusses the benefits of seaweed in human nutrition and its nutraceutical properties.
Offers different perspectives by presenting examples of commercial utilization of wild-harvested or cultivated algae, marine and freshwater seaweeds Discusses seasonal and cultivar variations in seaweeds for a better understanding of their implications in commercial applications Includes a wide range of micro and macro algae for food and feed production and provides perspectives on seaweed as a potential energy source

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Emerging Issues, Technologies and Systems

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Food Safety: Emerging Issues, Technologies and Systems offers a systems approach to learning how to understand and address some of the major complex issues that have emerged in the food industry. The book is broad in coverage and provides a foundation for a practical understanding in food safety initiatives and safety rules, how to deal with whole-chain traceability issues, handling complex computer systems and data, foodborne pathogen detection, production and processing compliance issues, safety education, and more. Recent scientific industry developments are written by experts in the field and explained in a manner to improve awareness, education and communication of these issues.
Examines effective control measures and molecular techniques for understanding specific pathogens Presents GFSI implementation concepts and issues to aid in implementation Demonstrates how operation processes can achieve a specific level of microbial reduction in food Offers tools for validating microbial data collected during processing to reduce or eliminate microorganisms in foods

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Steven Ricke, Janet R Donaldson, Carol A Phillips

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From Natural-origin Surfactants to Prospective Delivery Systems

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The on-going green trend in the personal care industry coupled with global environmental concerns, place natural-origin, biodegradable and skin-friendly surfactants such as alkyl polyglucosides (APGs) in high demand. After successful use in cosmetics, sufficient data has been obtained to welcome some sugar emulsifiers into the field of drug dosage. Alkyl Polyglucosides presents a comprehensive compendium which guides a researcher from the APG-related preformulation stages to formulation processing, including the investigation of various APG-stabilized systems skin performance. This book introduces various APG representatives, their benefits in relation to certain conventional surfactants, physicochemical and interfacial properties, possible interaction with commonly used ingredients and diverse characterization techniques indispensable for the assessment of colloidal systems. The first chapter introduces alkyl polyglucosides, followed by chapters on their properties, behaviour, an overview of the patent protection mechanisms and guidelines for submitting patent applications. Finally, a conclusion surveys international patent applications involving APGs.
Introduces the field of alkyl polyglucoside emulsifiers, listing all the contemporary and newly synthesized APG emulsifiers Provides detailed information on various aspects of APG-based structures Reveals potential of APG-stabilized vehicles as prospective delivery systems using several model drugs and cosmetic actives Includes an up-to-date review of research conducted in the field of APGs, facilitating future preformulation and formulation studies for researchers Offers a concise and practical compendium of characterization techniques

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Very few polymer mechanics problems are solved with only pen and paper today, and virtually all academic research and industrial work relies heavily on finite element simulations and specialized computer software. Introducing and demonstrating the utility of computational tools and simulations, Mechanics of Solid Polymers provides a modern view of how solid polymers behave, how they can be experimentally characterized, and how to predict their behavior in different load environments.

Reflecting the significant progress made in the understanding of polymer behaviour over the last two decades, this book will discuss recent developments and compare them to classical theories. The book shows how best to make use of commercially available finite element software to solve polymer mechanics problems, introducing readers to the current state of the art in predicting failure using a combination of experiment and computational techniques. Case studies and example Matlab code are also included.

As industry and academia are increasingly reliant on advanced computational mechanics software to implement sophisticated constitutive models and authoritative information is hard to find in one place - this book provides engineers with what they need to know to make best use of the technology available.
Helps professionals deploy the latest experimental polymer testing methods to assess suitability for applications Discusses material models for different polymer types Shows how to best make use of available finite element software to model polymer behaviour, and includes case studies and example code to help engineers and researchers apply it to their work

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ABC Transporters and Cancer provides invaluable information on the exciting and fast-moving field of cancer research. Here, outstanding and original reviews are presented on a variety of topics. This volume covers ABC transporters and cancer, and is suitable for researchers and students alike.
Provides information on cancer research Outstanding and original reviews Suitable for researchers and students

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Allergy, Immunity and Tolerance in Early Childhood

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Allergy, Immunity and Tolerance in Early Childhood: The First Steps of the Atopic March provides valuable insights on the atopic diseases, including asthma, allergic rhinitis, atopic dermatitis, and food allergies, which have developed into major health problems in most parts of the world.

As the natural history of these chronic diseases has been extensively studied, including their major genetic, environmental, and lifestyle determinants and potential protective factors, the book presents tactics on how pediatric allergists can provide early intervention. In addition, the book unites key, global experts in the field who summarize their collective, and current, knowledge of the early stage of the "Atopic March", along with novel ideas for potential options of prevention.
Summarizes the current knowledge of the epidemiological, genetic, and cellular basis of allergic diseases Ideal reference for the study of allergies in young children, atopic dermatitis, allergic rhinitis, childhood asthma, and food allergies Provides landmark findings in the field of immunology and allergy development Fulfills the need for a book that focuses on primary and secondary allergy prevention, especially during the first years of life Unites key, global experts in the field who summarize their collective, and current, knowledge, along with novel ideas for potential options of prevention

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Environmental Biotechnology: A Biosystems Approach, Second Edition presents valuable information on how biotechnology has acted as a vital buffer among people, pollution, and the environment. It answers the most important questions on the topic, including how, and why, a knowledge and understanding of the physical, chemical, and biological principles of the environment must be achieved in order to develop biotechnology applications.

Most texts address either the applications or the implications of biotechnology. This book addresses both. The applications include biological treatment and other environmental engineering processes. The risks posed by biotechnologies are evaluated from both evidence-based and precautionary perspectives. Using a systems biology approach, the book provides a context for researchers and practitioners in environmental science that complements guidebooks on the necessary specifications and criteria for a wide range of environmental designs and applications. Users will find crucial information on the topics scientific researchers must evaluate in order to develop further technologies.
Provides a systems approach to biotechnologies which includes the physical, biological, and chemical processes in context Presents relevant case studies on cutting-edge technologies, such as nanobiotechnologies and green engineering Addresses both the applications and implications of biotechnologies by following the lifecycle of a variety of established and developing biotechnologies Includes crucial information on the topics scientific researchers must evaluate in order to develop further technologies

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Food Safety and Quality Systems in Developing Countries

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Volume One: Export Challenges and Implementation Strategies

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Food Safety and Quality Systems in Developing Countries, Volume One: Export Challenges and Implementation Strategies considers both the theoretical and practical aspects of food safety and quality systems implementation by major world markets and new and emerging markets in developing countries. This reference examines issues facing exporters and importers of traditional foods the characteristics of the food and its distribution channels, and market access from a historical and current context to present best practices.

This must-have reference offers real-life, practical approaches for foods from around the world, offering help to those who have found it difficult to implement sustainable, certifiable food safety and quality systems into their businesses and provides scientifically sound solutions to support their implementation.
Includes accessible, relevant case studies of instances when food safety was compromised and offers practical scientific input in dealing with and preventing these issues Discusses the role and importance of research and documentation of food safety when exporting products Presents risk analysis examples from the past and present for products from various countries and different perspectives including the United States, Canada, Europe, Mexico, India, South Africa, Haiti, Jamaica, and more Offers successful strategies for developing food safety and quality systems from a national and firm-level perspective relevant to academics, regulators, exporters, importers and major distributors handling food from various developing countries

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Adenosine Receptors in Neurology and Psychiatry

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This well-established international series examines major areas of basic and clinical research within neuroscience, as well as emerging and promising subfields. This volume concentrates on adenosine receptor science, providing insights useful for actual drug discovery/development in neurology and psychiatry areas.
Expertise of contributors Subject including practical drug development from basic science, as translational research taste Structure of contents focusing on two CNS areas for diseases (neurology and psychiatry)

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Circadian Rhythms and Biological Clocks Part A

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Two new volumes of Methods in Enzymology continue the legacy of this premier serial with quality chapters authored by leaders in the field. Circadian Rhythms and Biological Clocks Part A and Part B is an exceptional resource for anybody interested in the general area of circadian rhythms. As key elements of timekeeping are conserved in organisms across the phylogenetic tree, and our understanding of circadian biology has benefited tremendously from work done in many species, the volume provides a wide range of assays for different biological systems.  Protocols are provided to assess clock function, entrainment of the clock to stimuli such as light and food, and output rhythms of behavior and physiology.  This volume also delves into the impact of circadian disruption on human health.  Contributions are from leaders in the field who have made major discoveries using the methods  presented here. Continues the legacy of this premier serial with quality chapters authored by leaders in the field  Covers research methods in biomineralization science Keeping with the interdisciplinary nature of the circadian rhythm field, the volume includes diverse approaches towards the study of rhythms, from assays of biochemical reactions in unicellular organisms to monitoring of behavior in humans.

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The Handbook of Nonwoven Filter Media, Second Edition provides readers with a fundamental understanding of nonwoven filter media. It is one of the few books dealing exclusively with the subject, and is primarily intended as a reference for people in the nonwovens industry (industry and academic researchers, technical, marketing , and quality control personnel) and universities offering courses in filtration theory and practice and nonwovens technology.The book includes applications for gas, liquid, and engine filtration, and identifies the types of filter media used in these applications. The various separation technologies that can be achieved with nonwoven filter media are revealed and discussed. Theoretical presentation is based on flow through porous media, and is developed around a nonwovens or engineered fabrics orientation. Presents the latest information on legislative, regulatory, environmental and sustainability issues affecting the nonwovens and filtration industries Includes a comprehensive discussion of Computational Flow Dynamics (CFD) by Dr. George Chase, University of Akron, USA Includes the latest Global and North American marketing statistics for filters and filter media prepared by Brad Kalil of INDA

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This well-established international series examines major areas of basic and clinical research within neuroscience, as well as emerging and promising subfields. This volume concentrates on Epigenetics
This book looks at Epigeneticsin the light of the newest scholarly discoveries and insights

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An Essential Toolkit for Modern VLSI Design

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Formal Verification: An Essential Toolkit for Modern VLSI Design presents practical approaches for design and validation, with hands-on advice to help working engineers integrate these techniques into their work. Formal Verification (FV) enables a designer to directly analyze and mathematically explore the quality or other aspects of a Register Transfer Level (RTL) design without using simulations. This can reduce time spent validating designs and more quickly reach a final design for manufacturing. Building on a basic knowledge of SystemVerilog, this book demystifies FV and presents the practical applications that are bringing it into mainstream design and validation processes at Intel and other companies. After reading this book, readers will be prepared to introduce FV in their organization and effectively deploy FV techniques to increase design and validation productivity.
Learn formal verification algorithms to gain full coverage without exhaustive simulation Understand formal verification tools and how they differ from simulation tools Create instant test benches to gain insight into how models work and find initial bugs Learn from Intel insiders sharing their hard-won knowledge and solutions to complex design problems

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Erik Seligman, Tom Schubert, M. V. Achutha Kiran Kumar

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Modulation of Sleep by Obesity, Diabetes, Age, and Diet

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Sleep disorder is a rampant problem in the US, with over 40 million Americans currently diagnosed according to the NIH. There is a clear association between sleep disorder and a wide range of other human disorders performance deficiencies, psychiatric illnesses, heart disease, obesity and more but in spite of this there is not yet a convenient overview on the market detailing the impact of obesity, age, diabetes and diet on sleep duration and attendant health outcomes. This volume focuses on the interaction between sleep and these factors, with special attention being paid to the potential for neurological modulation of sleep via diet. The volume aid readers in understanding the role each of these factors plays in sleep architecture and its regulation by circadian biology and neurology.
Aids in understanding the impact of age, diet, obesity and disease on sleep Offers focus on neurological changes that affect metabolism Explores diabetes induced sleep problems Aid to understanding the multifactorial causes of age-related sleep dysfunction Addresses selected studies of nutraceuticals affecting sleep for potential application clinically Discusses major impact on sleep disorders by caffeine and alcohol