# data[].attributes.description
Epilepsy is one of the most common neurological disorders, and original observations in the field are often the key to diagnosis and successful treatment. Physicians new to the field as well as seasoned practitioners will benefit from more than one hundred case vignettes that explore the universe of epilepsy as it presents in daily practice. Some of these cases challenge long-held views about epilepsy and others bring the reader to the limits of our understanding of epilepsy, both in clinical and basic science. To improve the interface of clinical and basic science in epilepsy, basic scientists comment on the potential mechanisms underlying clinical observations, and clinicians assess the potential impact of recent results of experiments in the laboratory. Puzzling Cases of Epilepsy highlights the importance that original observations have in inspiring both new treatments and continued research. Presents unique and challenging case vignettes in epilepsy contributed by eminent physicians in the field Provides practicing physicians with examples of how baffling cases were handled and solved A new section provides a translational perspective, with basic scientists discussing the potential mechanisms underlying original clinical observations, and clinical scientists discussing the clinical implications of experiments in the epilepsy laboratory

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Handbook of the Neuroscience of Language

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In the last ten years the neuroscience of language has matured as a field. Ten years ago, neuroimaging was just being explored for neurolinguistic questions, whereas today it constitutes a routine component. At the same time there have been significant developments in linguistic and psychological theory that speak to the neuroscience of language. This book consolidates those advances into a single reference.

The Handbook of the Neuroscience of Language provides a comprehensive overview of this field. Divided into five sections, section one discusses methods and techniques including clinical assessment approaches, methods of mapping the human brain, and a theoretical framework for interpreting the multiple levels of neural organization that contribute to language comprehension. Section two discusses the impact imaging techniques (PET, fMRI, ERPs, electrical stimulation of language cortex, TMS) have made to language research. Section three discusses experimental approaches to the field, including disorders at different language levels in reading as well as writing and number processing. Additionally, chapters here present computational models, discuss the role of mirror systems for language, and cover brain lateralization with respect to language. Part four focuses on language in special populations, in various disease processes, and in developmental disorders. The book ends with a listing of resources in the neuroscience of language and a glossary of items and concepts to help the novice become acquainted with the field.

Editors Stemmer & Whitaker prepared this book to reflect recent developments in neurolinguistics, moving the book squarely into the cognitive neuroscience of language and capturing the developments in the field over the past 7 years.
History section focuses on topics that play a current role in neurolinguistics research, aphasia syndromes, and lesion analysis Includes section on neuroimaging to reflect the dramatic changes in methodology over the past decade Experimental and clinical section reflects recent developments in the field

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Hierarchical Modeling and Inference in Ecology

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The Analysis of Data from Populations, Metapopulations and Communities

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A guide to data collection, modeling and inference strategies for biological survey data using Bayesian and classical statistical methods.

This book describes a general and flexible framework for modeling and inference in ecological systems based on hierarchical models, with a strict focus on the use of probability models and parametric inference. Hierarchical models represent a paradigm shift in the application of statistics to ecological inference problems because they combine explicit models of ecological system structure or dynamics with models of how ecological systems are observed. The principles of hierarchical modeling are developed and applied to problems in population, metapopulation, community, and metacommunity systems.

The book provides the first synthetic treatment of many recent methodological advances in ecological modeling and unifies disparate methods and procedures.
The authors apply principles of hierarchical modeling to ecological problems, including

* occurrence or occupancy models for estimating species distribution
* abundance models based on many sampling protocols, including distance sampling
* capture-recapture models with individual effects
* spatial capture-recapture models based on camera trapping and related methods
* population and metapopulation dynamic models
* models of biodiversity, community structure and dynamics Wide variety of examples involving many taxa (birds, amphibians, mammals, insects, plants) Development of classical, likelihood-based procedures for inference, as well as Bayesian methods of analysis Detailed explanations describing the implementation of hierarchical models using freely available software such as R and WinBUGS Computing support in technical appendices in an online companion web site

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Molecular and Therapeutic Insights From Model Systems

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Parkinsons disease is the second most prevalent neurodegenerative disease and is characterized by the irreversible loss of dopamine neurons. Despite its high prevalence in society and many decades of research, the origin of the pathogenesis and the molecular determinants involved in the disorder has remained elusive. Confounding this issue is the lack of experimental models that completely recapitulate the disease state. The identification of a number of genes thought to play a role in the cell death, and development of both toxin and genetic models to explore the function of the genes both in unaffected and diseased cells are now providing new insights into the molecular basis of the neurodegeneration, as well as therapeutic approaches. In this reference, we will describe the advances and the advantages that various invertebrates, cell culture, rodents, and mammals provide in the identification of the molecular components and mechanisms involved in the cell death, and outline the opportunities that these systems provide in drug discovery. Comprehensive and critical assessment of the utility of various model systems to identify the molecular components and pathways involved in Parkinsons disease Describes the power of toxin and genetic models to identify novel therapeutic targets and compounds that can be used in PD Current overviews of current status of PD research and discovery from bench-to-bedside Provides novel insights and views on where the future of PD research may lead Provides a powerful teaching tool and template to explore the utility of model systems to identify molecular pathways, molecular targets, and therapeutics that are applicable to a variety of neurological diseases

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Tracking Animal Migration with Stable Isotopes

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Tracking Animal Migration with Stable Isotopes provides a consolidated overview of the current knowledge of stable isotopes in terrestrial migration research questions. It offers ecologists and conservation biologists provide a practical handbook for those considering using stable isotopes in their migration research. Presents information for readers to understand how to apply isotopic methods for tracking Critical information on areas for future research Practical guidelines and discussions of sample collection, sample preparation, and data analysis Enhanced understanding of data and statistical analysis in isotope-based studies of migratory animals

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The Bioarchaeology of Metabolic Bone Disease

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The Bioarchaeology of Metabolic Bone Disease provides a comprehensive and invaluable source of information on this important group of diseases.  It is an essential guide for those engaged in either basic recording or in-depth research on human remains from archaeological sites.  The range of potential tools for investigating metabolic diseases of bone are far greater than for many other conditions, and building on clinical investigations, this book will consider gross, surface features visible using microscopic examination, histological and radiological features of bone, that can be used to help investigate metabolic bone diseases. Clear photographs and line drawings illustrate gross, histological and radiological features associated with each of the conditions Covers a range of issues pertinent to the study of metabolic bone disease in archaeological skeletal material, including the problems that frequent co-existence of these conditions in individuals living in the past raises, the preservation of human bone and the impact this has on the ability to suggest a diagnosis of a condition Includes a range of conditions that can lead to osteopenia and osteoporosis, including previous investigations of these conditions in archaeological bone

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Principles and Practice of Clinical Trial Medicine

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Clinical trials are an important part of medicine and healthcare today, deciding which treatments we use to treat patients. Anyone involved in healthcare today must know the basics of running and interpreting clinical trial data. Written in an easy-to-understand style by authors who have considerable expertise and experience in both academia and industry, Principles and Practice of Clinical Trial Medicine covers all of the basics of clinical trials, from legal and ethical issues to statistics, to patient recruitment and reporting results. Jargon-free writing style enables those with less experience to run their own clinical trials and interpret data Book contains an ideal mix of theory and practice so researchers will understand both the rationale and logistics to clinical trial medicine Expert authorship whose experience includes running clinical trials in an academic as well as industry settings Numerous illustrations reinforce and elucidate key concepts and add to the book's overall pedagogy

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A Guide for Authors, Editors, and Researchers

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Much like the Chicago Manual of Style, The Manual of Scientific Style addresses all stylistic matters in the relevant disciplines of physical and biological science, medicine, health, and technology. It presents consistent guidelines for text, data, and graphics, providing a comprehensive and authoritative style manual that can be used by the professional scientist, science editor, general editor, science writer, and researcher. Scientific disciplines treated independently, with notes where variances occur in the same linguistic areas Organization and directives designed to assist readers in finding the precise usage rule or convention A focus on American usage in rules and formulations with noted differences between American and British usage Differences in the various levels of scientific discourse addressed in a variety of settings in which science writing appears Instruction and guidance on the means of improving clarity, precision, and effectiveness of science writing, from its most technical to its most popular

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Principles of Biomedial Informatics provides a foundation for understanding the fundamentals of biomedical informatics, which deals with the storage, retrieval, and use of biomedical data for biological problem solving and medical decision making. It covers the application of these principles to the three main biomedical domains of basic biology, clinical medicine, and public health. The author offers a coherent summary, focusing on the three core concept areas of biomedical data and knowledge representation: biomedical information access, biomedical decision making, and information and technology use in biomedical contexts. Develops principles and methods for representing biomedical data, using information in context and in decision making, and accessing information to assist the medical community in using data to its full potential Provides a series of principles for expressing biomedical data and ideas in a computable form to integrate biological, clinical, and public health applications Includes a discussion of user interfaces, interactive graphics, and knowledge resources and reference material on programming languages to provide medical informatics programmers with the technical tools to develop systems

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Marine Mammals of the World: A Comprehensive Guide to Their Identification

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With coverage on all the marine mammals of the world, authors Jefferson, Webber, and Pitman have created a user-friendly guide to identify marine mammals alive in nature (at sea or on the beach), dead specimens in hand, and also to identify marine mammals based on features of the skull. This handy guide provides marine biologists and interested lay people with detailed descriptions of diagnostic features, illustrations of external appearance, beautiful photographs, dichotomous keys, and more. Full color illustrations and vivid photographs of every living marine mammal species are incorporated, as well as comprehendible maps showing a range of information. For readers who desire further consultation, authors have included a list of literature references at the end of each species account. For an enhanced understanding of habitation, this guide also includes recognizable geographic forms described separately with colorful paintings and photographs. All of these essential tools provided make Marine Mammals of the World the most detailed and authoritative guide available!

* Contains superb photographs of every species of marine mammal for accurate identification
* Authors collective experience adds up to 80 years, and have seen nearly all of the species and distinctive geographic forms described in the guide
* Provides the most detailed and anatomically accurate illustrations currently available
* Special emphasis is placed on the identification of species in problem groups, such as the beaked whales, long-beaked oceanic dolphin, and southern fur seals
* Includes a detailed list of sources for more information at the back of the book.

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Thomas Allen Jefferson, Marc A. Webber, Robert L. Pitman, Brett Jarrett

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The Evolution of Hemispheric Specialization in Primates

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Hemispheric specialization, and lateralized sensory, cognitive or motor function of the left and right halves of the brain, commonly manifests in humans as right-handedness and left hemisphere specialization of language functions. Historically, this has been considered a hallmark of, and unique to, human evolution. Some theories propose that human right-handedness evolved in the context of language and speech while others that it was a product of the increasing motor demands associated with feeding or tool-use. In the past 20-25 years, there has been a plethora of research in animals on the topic of whether population-level asymmetries in behavioral processes or neuro-anatomical structures exist in animals, notably primates and people have begun to question the historical assumptions that hemispheric specialization is unique to humans. This book brings together various summary chapters on the expression of behavioral and neuro-anatomical asymmetries in primates. Several chapters summarize entire families of primates while others focus on genetic and non-genetic models of handedness in humans and how they can be tested in non-human primates. In addition, it makes explicit links between various theoretical models of the development of handedness in humans with the observed patterns of results in non-human primates. A second emphasis is on comparative studies of handedness in primates. There is now enough data in the literature across different species to present an evolutionary tree for the emergence of handedness (and perhaps other aspects of hemispheric specialization, such as neuro-anatomical asymmetries) and its relation to specific morphological and ecological adaptations in various primate species.

* The first treatment of this important topic since 1998* Examines the tenet that lateralization and handedness is a uniquely human character through evidence from higer and lower primates and with reference to other vertebrates.* Advances our understanding of the occurrence, evolution and significance of lateralization and handedness effects.

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Practical Guide to Clinical Computing Systems

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The development of clinical computing systems is a rapidly growing priority area of health information technology, spurred in large measure by robust funding at the federal and state levels. It is widely recognized as one of the key components for reducing costs and improving the quality of care. At the same time as more and more hospitals and clinics are installing clinical computing systems, major issues related to design, operations, and infrastructure remain to be resolved. This book tackles these critical topics, including system selection, configuration, installation, user support, interface engines, and long-term operation. It also familiarizes the reader with regulatory requirements, budgetary issues, and other aspects of this new electronic age of healthcare delivery.

It begins with an introduction to clinical computing and definition of key terminology. The next several chapters talk about system architecture and interface design, followed by detailed discussion of all aspects of operations. Attention is then given to the realities of leadership, planning, oversight, budgeting, and employee recruitment. This invaluable resource includes a special section that talks about career development for students and others interested in entering the field.

*Provides a complete overview of practical aspects
*Detailed guidance on the design and operation of clinical computing systems
*Discusses how clinical computing systems relate to health care organization committees and organizational structure
*Includes numerous real-life examples with expert insights on how to avoid pitfalls

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Wine Science, Third Edition, covers the three pillars of wine science grape culture, wine production, and sensory evaluation. It takes readers on a scientific tour into the world of wine by detailing the latest discoveries in this exciting industry.

From grape anatomy to wine and health, this book includes coverage of material not found in other enology or viticulture texts including details on cork and oak, specialized wine making procedures, and historical origins of procedures. Author Ronald Jackson uniquely breaks down sophisticated techniques, allowing the reader to easily understand wine science processes.

This updated edition covers the chemistry of red wine color, origin of grape varietyies, wine language, significance of color and other biasing factors to wine perception, various meanings and significance of wine oxidation. It includes significant additional coverage on brandy and ice wine production as well as new illustrations and color photos.

This book is recommended for grape growers, fermentation technologists; students of enology and viticulture, enologists, and viticulturalists.
NEW to this edition:

* Extensive revision and additions on: chemistry of red wine color, origin of grape varietyies, wine language, significance of color and other biasing factors to wine perception, various meanings and significance of wine oxidation
* Significant additional coverage on brandy and ice wine production
* New illustrations and color photos

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Gluten-Free Cereal Products and Beverages

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Gluten-Free Cereal Products and Beverages is the only book to address gluten-free foods and beverages from a food science perspective. It presents the latest work in the development of gluten-free products, including description of the disease, the detection of gluten, and the labeling of gluten-free products as well as exploring the raw materials and ingredients used to produce gluten-free products.

Identifying alternatives to the unique properties of gluten has proven a significant challenge for food scientists and for the 1% of the worlds population suffering from the immune-mediated entropathy reaction to the ingestion of gluten and related proteins, commonly known as Celiac Disease. This book includes information on the advances in working with those alternatives to create gluten free products including gluten-free beer, malt and functional drinks.

Food scientists developing gluten-free foods and beverages, cereal scientists researching the area, and nutritionists working with celiac patients will find this book particularly valuable.
Written by leading experts, presenting the latest developments in gluten-free products Addresses Coeliac Disease from a food science perspective Presents each topic from both a scientific and industrial point of view

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In today's industrialized societies, the majority of parents work full time while caring for and raising their children and managing household upkeep, trying to keep a precarious balance of fulfilling multiple roles as parent, worker, friend, & child. Increasingly demands of the workplace such as early or late hours, travel, commute, relocation, etc. conflict with the needs of being a parent. At the same time, it is through work that people increasingly define their identity and self-worth, and which provides the opportunity for personal growth, interaction with friends and colleagues, and which provides the income and benefits on which the family subsists. The interface between work and family is an area of increasing research, in terms of understanding stress, job burn out, self-esteem, gender roles, parenting behaviors, and how each facet affects the others.

The research in this area has been widely scattered in journals in psychology, family studies, business, sociology, health, and economics, and presented in diverse conferences (e.g., APA, SIOP, Academy of Management). It is difficult for experts in the field to keep up with everything they need to know, with the information dispersed. This Handbook will fill this gap by synthesizing theory, research, policy, and workplace practice/organizational policy issues in one place.

The book will be useful as a reference for researchers in the area, as a guide to practitioners and policy makers, and as a resource for teaching in both undergraduate and graduate courses.

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Karen Korabik, Donna S. Lero, Denise L. Whitehead

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What Can Nanotechnology Learn From Biotechnology?

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Social and Ethical Lessons for Nanoscience from the Debate over Agrifood Biotechnology and GMOs

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What Can Nanotechnology Learn From Biotechnology? presents diverse perspectives on biotechnology and nanotechnologies. Avoiding extreme perspectives, unwarranted hype and absolute rejection, this book explores the diverse territory of proponents and opponents of challenging but potentially risky technologies. Contributions from recognized experts in their fields represent the perspectives of a diverse range of stakeholders.

This book details the lessons to be learned from the controversy over genetically modified foods, and how those lessons can be applied to developing nanotechnologies, particularly agricultural and other food-related applications. Exploring the environmental, social and ethical impact of nanotechnology in addition to the technical and economical impacts, it an ideal reference for any scientist, engineer, research program administrator, resource allocator, and NGO advocate.
Addresses the growing concern over the responsibility of science to the impacted population Uses real-world experience to outline practical approaches for emerging technologies Addresses the concerns of science as well as social science

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This unique reference provides a primary source for osteologists and the medical/legal community for the understanding of burned bone remains in forensic or archaeological contexts. It describes in detail the changes in human bone and soft tissues as a body burns at both the chemical and gross levels and provides an overview of the current procedures in burned bone study. Case studies in forensic and archaeological settings aid those interested in the analysis of burned human bodies, from death scene investigators, to biological anthropologists looking at the recent or ancient dead. Includes the diagnostic patterning of color changes that give insight to the severity of burning, the positioning of the body, and presence (or absence) of soft tissues during the burning event Chapters on bones and teeth give step-by-step recommendations for how to study and recognize burned hard tissues

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Fundamental Neuroscience, Third Edition introduces graduate and upper-level undergraduate students to the full range of contemporary neuroscience. Addressing instructor and student feedback on the previous edition, all of the chapters are rewritten to make this book more concise and student-friendly than ever before. Each chapter is once again heavily illustrated and provides clinical boxes describing experiments, disorders, and methodological approaches and concepts.Capturing the promise and excitement of this fast-moving field, Fundamental Neuroscience, 3rd Edition is the text that students will be able to reference throughout their neuroscience careers! 30% new material including new chapters on Dendritic Development and Spine Morphogenesis, Chemical Senses, Cerebellum, Eye Movements, Circadian Timing, Sleep and Dreaming, and Consciousness Additional text boxes describing key experiments, disorders, methods, and concepts Multiple model system coverage beyond rats, mice, and monkeys Extensively expanded index for easier referencing

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Larry Squire, Darwin Berg, Floyd E. Bloom, Sascha du Lac, Anirvan Ghosh, Nicholas C. Spitzer, Larry R. Squire, Floyd E. Bloom, Nicholas C. Spitzer

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An Introduction to Behavioral Evidence Analysis

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Now in its third edition, Criminal Profiling is established as an industry standard text. It moves evidence-based criminal profiling into a full embrace of the scientific method with respect to examining and interpreting behavioral evidence. If focuses on criminal profiling as an investigative and forensic process, helping to solve crime through an honest understanding of the nature and behavior of the most violent criminals. Throughout the text, the author outlines specific principles and practice standards for Behavioral Evidence Analysis, focusing on the application of theory and method to real cases.  Criminal Profiling, Third Edition, is an ideal companion for students and professionals alike, including investigators, forensic scientists, criminologists, mental health professionals, and attorneys. With contributing authors representing law enforcement, academic, mental health, and forensic science communities, it offers a balanced perspective not found in other books on this subject. Readers will use it as a comprehensive reference text, a handbook for evaluating physical evidence, a tool to bring new perspectives to cold cases, and as an aid in preparing for criminal trials. Best-selling author Brent Turvey defines the deductive profiling method, which focuses on examining the nature and behavior of criminals in order to solve crimes Contributing authors represent law enforcement, academic, mental health, and forensic science communities for a balanced perspective Completely revised with 35% new material including updates on the latest advances in evidence-based profilingNew to this edition New cases in every chapter New chapters in logic and reasoning New chapter reviewing non-evidence based profiling methods New chapter on mass homicide New chapter on terrorist profiling and interviewing

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Cellular and Molecular Neurophysiology, Third Edition, is the new, thoroughly revised edition of the only current, established, and authoritative text focusing on the cellular and molecular physiology of nerve cells. Previously titled Cellular and Molecular Neurobiology, the new title better reflects this focus. This version contains 80% new or updated material.

Fifteen appendices describing neurobiological techniques are interspersed in the text. Now in full color throughout, the book has over 400 carefully selected and constructed illustrations. It includes an instructor website with all the images in electronic format, plus additional material. The book is hypothesis driven rather than just presenting the facts, and the content is firmly based on numerous experiments performed by the top experts in the field.

While covering the important facts, the book also presents the background for how researchers arrived at this knowledge to provide a context for the field. It promotes a real understanding of the function of nerve cells that is useful for practicing neurophysiologists and students in a graduate-level course on the topic alike.
* 80% new or updated material* Fifteen appendices describing neurobiological techniques are interspersed in the text* Now in full color throughout, with more than 400 carefully selected and constructed illustrations* Provides an instructor website with all the images in electronic format, plus additional material