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"This is a 'go-to' reference text for a serious cytologist. " Reviewed by: Kathleen Tennant on behalf of Veterinary Record, November 2015

- Comprehensive coverage of all body systems and body fluids  and the pathological changes associated with various infectious agents  emphasizes areas in which the application of cytology has the greatest diagnostic value.
- Exceptional-quality, full-color photomicrographs show both normal and abnormal tissue and also include detailed legends.
- Discussions of clinical, differential, and cytological diagnosis accompany the illustrations of lesions and conditions in each chapter.
- Helpful hints for improving specimen quality are provided in discussions of common errors and problems encountered in the preparation of cytological specimens.
- Coverage of histology in organ system chapters demonstrates the histological or histopathologic corollary of cytologic findings.
- Clear, concise descriptions include sampling techniques, slide preparation and examination, and guidelines for interpretation, leading to accurate in-house and commercial laboratory diagnosis.
- Easy-to-use, well-organized format includes many tables, algorithms, boxes, and Key Point callouts for at-a-glance reference.
- NEW! Chapter on Fecal Cytology
- Highlighted boxes featuring Key Points provide helpful tips for best conceptual understanding and diagnostic effectiveness
- Photomicrographs now include more comparative histology
- Discussions of broader uses of stains and immunocytochemistry for differential cytologic characterization
- Expanded chapter on Advanced Diagnostic Techniques includes more methodology and application of current tools, representing advances in both aspiration and exfoliative cytology.

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Current Topics in Transplantation, An Issue of Surgical Clinics

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An important review on transplantation for the general surgeon! Topics include: kidney transplant, left lobe liver transplants, advances in lung transplantation, stem cell and cellular transplants, pancreatectomy, management of organ failure, transplant immune suppression, antibody mediated rejection, cardiac assist devices, organ perfusion and preservation, weight reduction therapy, organ allocation and distribution, and more!

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Late Life Depression, An Issue of Psychiatric Clinics

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Apart from Alzheimer's dementia, depressive disorders are emerging to account for the next greatest share of disability among older adults. Depressive illnesses complicate the recovery of many important medical illnesses and are associated with suicide death in the elderly at rates exceeding those seen in young adults. This issue of Psychiatric Clinics provides information for general adult psychiatrists, internal medicine geriatricians, and primary care physicians and care extenders to enable them to meet the most basic needs of depressed older adults. Topics in this issue address the questions: What is late life depression? What are the unique cognitive deficits seen in late life depression? What is the nature of the two-way relationship between medical illness and depression in late life depression? What complications arise from late life depression? What is the relationship between late life depression and dementing illnesses? What assessments should be done of the person with suspected late life depression? What are the psychological treatments for late life depression? What is the role of medications in late life depression? What is the role of alternative treatments in late life depression? Is there a role for ECT/TMS/VNS in late life depression? Vaughn McCall of Georgia Health Sciences University provides his expertise to lead this issue.

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Obstructive Sleep Apnea, An Issue of Sleep Medicine Clinics

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This issue of Sleep Medicine Clinics will be Guest Edited by Jim Barker, MD CPE, FACP, FCCP, FAASM Shirley Fong Jones, MD, FCCP of Scott and White Memorial Hospital and will focus on Obstructive Sleep Apnea. Article topics include Weight loss, Pharmacologic therapy of obstructive sleep apnea, Alternative Therapies, Masks and Interfaces, Outcomes of treatment of hypersomnia for OSA, Effects of therapy on CV outcomes, Complex Sleep Apnea, Oral appliances, Cost of therapy, Medicolegal aspects of treatment, Residual sleepiness, Therapy and Metabolic Outcomes, and Therapies for Children with OSA.

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Clinical Neurogenetics, An Issue of Neurologic Clinics

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This issue of Neurologic Clinics features a review of clinical neurogenetics as it pertains to the following disorders: Huntington Disease; Autism/ASD;Fragile X Tremor Ataxia Syndrome (FXTAS); Lysosomal Storage Diseases; Psychiatric Disorders; Dominant Spinocerebellar Ataxias; Metabolic Disorders; Friedreich Ataxia; ALS; Dementia; Neuromuscular Disorders; Stroke; Epilepsy; and Dystonia.

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Orthopedics, An Issue of Primary Care Clinics in Office Practice

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This issue of Primary Care: Clinics in Office Practice features expert clinical reviews on Orthopedics which includes current information on . The Preparticipation Physical Examination, Exercise Prescription, Diagnosis and Treatment of Osteoarthritis, Evaluation and Treatment of Cervical Radiculopathy, Choosing the Right Diagnostic Imaging Modality in Musculoskeletal Diagnosis, Evaluation and Treatment of Musculoskeletal Chest Pain, Evaluation and Treatment of Rotator Cuff Pathology, Evaluation and Treatment of Sternoclavicular, Clavicular, and Acromioclavicular Injuries, Evaluation and Treatment of Upper Extremity Nerve Entrapment Syndromes, Complementary and Alternative Treatments in Musculoskeletal Medicine, Evaluation and Treatment of Biking and Running Injuries, Common Injections in Musculoskeletal Medicine, and Considerations in Footwear and Orthotics.

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Procedures in the Office Setting, An Issue of Obstetric and Gynecology Clinics

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Gynecology is a procedure-related field that, like other specialties, has moved toward minimally invasive procedures that can be performed in the office setting. This issue of the Obstetrics and Gynecology Clinics covers the most commonly performed gynecologic procedures performed in the office setting. Colposcopy, Cryosurgery, LEEP, sterilization, D and C, and Urogynecologic procedures are all covered, along with articles on surgically implanted contraceptives and surgical abortion.

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Moderate Preterm, Late Preterm, and Early Term Births, An Issue of Clinics in Perinatology

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This issue is expected to be in high demand, being extremely valuable to both neonatologists and maternal-fetal medicine physicians. The Guest Editors have put together a very comprehensive issue that looks at the premature infant. Topics include: Moderate Preterm. Late Preterm and Early Term Births: Epidemiology and Trends; Stillbirth Reduction Efforts and Impact on Early Births; Management of Indicated Early Term and Late Preterm Births; Physiological Underpinnings for Clinical Problems in Moderately Preterm, Late Preterm;Brain Maturation in the Second of Half of Pregnancy; Respiratory Disorders in Moderately Preterm, Late Preterm and Early Term Infants; Metabolic and Neurologic Issues in Moderately Preterm, Late Preterm and Early Term Infants; and Quality Initiatives Related to Moderately Preterm, Late Preterm and Early Term Births.

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Pediatric Hematology, An Issue of Pediatric Clinics

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This issue will assist the practicing pediatrician with providing evidence-based care to children with common, rare, inherited and acquired hematological disorders whom they regularly see in general pediatric practice. The information in this edition will support a general pediatrician's understanding of recently developed diagnostic and therapeutic tools--for instance, techniques for the assessment of transfusional iron overload in chronically transfused patients  resulting in better surveillance of medication side effects and improved support for patients who are prescribed with complex chelation regimens. New, improved therapeutic approaches to treatment of children with venous thromboembolic disease have recently been introduced; affected patients often require close monitoring in their communities through the general pediatrician whose practice will be enhanced by information that has been prepared by pediatric specialists with pediatric patients in mind.

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Drug Hepatotoxicity, An Issue of Clinics in Liver Disease

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Dr. Pyrsopolous has created a comprehensive review on the most important and timely topics in drug heptatotoxicity. He has arraanged for there to be a full span of very basic articles that discuss drug metabolism, hepatotoxicity, and drug-induced acute liver failure as well as other important articles devoted to clinical manifestations and treatment of drug induced hepatotoxicity; Pathological manifestations of drug induced hepatotoxicity; Drug induced cholestasis; Lipid lowering agents induced hepatotoxicity; Herbal ,complementary and alternative medicine induced liver injury; Antiretroviral and anti - HCV DAA related hepatotoxicity; Antibiotic related hepatotoxicity; Acetaminophen related hepatoxicity; NSAIDS induced hepatoxocity; Chemotherapy induced hepatotoxicity; Anti epileptic induced hepatotoxicity; and steatohepatitis induced by drugs.

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Molecular Pathology, An Issue of Clinics in Laboratory Medicine

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Molecular pathology has significantly matured over the past decade to establish itself as a discipline in its own right. Patient diagnosis, prognosis, management and care have been influenced by molecular pathology testing algorithms on a global scale. Whether it pertains to carrier status of deleterious genes, diagnosis by molecular techniques, assessment of appropriate remission post treatment, parentage or forensics testing  molecular pathology continues to increase its presence and influence in the diagnostic laboratory armamentarium. Furthermore, intellectualization and proprietization of molecular pathology with respect to the discovery of new genes and or new techniques continues to pose new challenges of test ownership, legalities, liabilities, widespread acceptance and utility. This issue of Laboratory Clinics seeks to provide selective state of the art understanding of molecular pathology with respect to its relationship to key pathology disciplines as well as the current challenges and promise for the future.

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Innovations in the Cavus Foot Deformity, An Issue of Foot and Ankle Clinics

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This issue of Foot and Ankle Clinics will focus on all aspects of surgical treatment of Cavus foot deformities, from an orthopedic standpoint. It will cover related surgical techniques to revise problems in the forefoot, arch, and ankle (all are affected by the disease). It will also address specific instances, such as pediatric patients, and cases where total ankle arthroplasty are required.

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Disorders of the Anorectum and Pelvic Floor, An Issue of Gastroenterology Clinics

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This issue provides important updates on the management of disorders of the anorectum and pelvic floor. Expert authors provide information on hemorrhoidal issues, anorectal anatomy and imaging techniques, fissure and anal stenosis, rectal prolapse, and anal abscess and fistula. Other articles are devoted to sexually transmitted and infectious diseases, treatment of radiation proctitis, and pruiritis ani. Readers will come away with a full understanding of the current strategies for diagnosis and management of these disorders.

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Update in Sexually Transmitted Infections, an Issue of Infectious Disease Clinics

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This issue of the Infectious Disease Clinics is devoted to the treatment and prevention of the most common STDs  including syphilis, gonorrhea, herpes, and HPV. The articles will discuss the current research in the field such as antimicrobial resistance in treating gonorrhea and the development/trials of a genital herpes vaccine.

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Acute and Chronic Complications of Diabetes, An Issue of Endocrinology and Metabolism Clinics

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This issue of Endocrinology Clinics brings the reader up to date on the important advances in research surrounding acute diabetic complications. Guest edited by Leonid Poretsky and Eliana Liao, the topics covered include retinopathy, neuropathy, gastrointestinal complications, diabetic foot, dental complications, dermatologic complications, and more.

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Transplantation, An Issue of Anesthesiology Clinics

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This issue of Anesthesiology Clinics covers the latest updates in transplantation written by the world-leading experts on the topic. Procedurally-focused articles cover best practices in patient selection, intraoperative care, postoperative care, organ donor management and more. Achieve the best outcomes and keep current on this area of anesthesia practice.

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Shoulder Instability in the Athlete, An Issue of Clinics in Sports Medicine

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This issue of Clinics in Sports Medicine focuses on anatomy and biomechanics and includes exam and imagine, surgical timing, and covers a variety of conditions. Internal impingement, multi-directional instability, bone loss, revision surgery, posterior instability, and a variety of other clinical conditions are thoroughly addressed. In addition, there are also chapters on both contact and non-contact athletes, instability in pediatric patients and rehabilitation.

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Clinical and Electrophysiologic Management of Syncope, An Issue of Cardiac Electrophysiology Clinics

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This issue of Cardiac Electrophysiology Clinics devoted to syncope a disorder that is associated with increased mortality. Internationally recognized experts discuss the many causes of syncope, helping the clinician to distinguish life-threatening etiologies from benign ones.

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Computer-Guided Dental Implants and Reconstructive Surgery

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Written by recognized dental implant surgery experts Marco Rinaldi, Scott Ganz, and Angelo Mottola, Computer-Guided Applications for Dental Implants, Bone Grafting, and Reconstructive Surgery is the first text to provide state-of-the-art information on procedures and techniques used in guided dental implant surgery and bone grafting. It begins with the basic principles of guided dental implants including anatomical obstacles, pathologies, and pharmacological management of patients, and then uses a templated, atlas format to discuss clinical case studies. With a companion website includes videos demonstrating surgical procedures, this text makes it easier for the entire surgical team to share in the diagnosis and treatment planning for patients receiving implants.

- Coverage of computer-guided surgery from treatment planning to recovery includes a combination of actual 3-D computed imagery and clinical photos to clearly demonstrate implant surgeries.
- Bone grafting protocols address 3-D evaluation of bone density and the use of bone grafts to augment bone volume prior to dental implant surgery.
- 40 case studies include pre- and post-operative considerations as well as the description of the surgical procedure, using high-quality clinical photos as well as CT and 3-D images to clearly illustrate every guided-implant challenge.
- Over 1,800 full-color images include pre-, intra-, and post-operative photographs, showing pathologies, procedures, and outcomes.
- Expert, authoritative authors provide guidance based upon extensive experience with current techniques as well as the latest technological advances in guided-implant surgery.
- A companion website includes 10 video clips that are linked to selected clinical cases in the text.
- Digital book formats supplement the print book, making this reference easy to access on iPads, tablets, e-readers, and smart phones.

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Marco Rinaldi, Scott D Ganz, Angelo Mottola

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COPD, An Issue of Clinics in Chest Medicine

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This issue of Clinics in Chest Medicine is Guest Edited by Peter J. Barnes FRS, FMedSci from Imperial College London and will fosus on COPD. Article topics include epidemiology, pathophysiology, cellular and molecular mechanisms and comorbidities of COPD, diagnosis and phenotype of COPD, pulmonary rehabilitation, asthma and COPD, biomarkers, bronchodilators, non invasive ventialtion, and new drug therapies.