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This third edition of Fish Nutrition is a comprehensive treatise on nutrient requirements and metabolism in major species of fish used in aquaculture or scientific experiments. It covers nutrients required and used in cold water, warm water, fresh water, and marine species for growth and reproduction. It also highlights basic physiology and biochemistry of the nutrients and applications of these principles to scientific and practical diet formulations and to manufacturing techniques for major species used worldwide in aquaculture.

*Nutrient requirements for dietary formulations for fish farming*Digestive physiology*Comparative nutritional requirements of different species*Fish as unique animals for certain metabolic pathways

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International Review of Cytology presents current advances and comprehensive reviews in cell biology-both plant and animal. Articles address structure and control of gene expression, nucleocytoplasmic interactions, control of cell development and differentiation, and cell transformation and growth. Authored by some of the foremost scientists in the field, each volume provides up-to-date information and directions for future research. Structural and Functional Evolution of the Natriuretic Peptide System in Vertebrates The Kinetochore of Higher Eukaryotes Mitochondrial Proteins at Unexpected Cellular Locations The Petite Mutation in Yeast Effects on Stress on Cellular Infrastructure and Metabolic Organization in Plant Cells

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Apoptosis provides a current and comprehensive collection of methods for the study of cell death. Using a diverse range of technical approaches and model systems, the chapters in this volume cover topics from the cellular and organismal to the molecular and anatomical. The methods are illustrated with user-friendly recipes and over 100 tables, halftones, and diagrams. Current methodologies for studying cell death Wide range of model systems  Molecular, biochemical, cellular, and genetic approaches Complements the original Cell Death volume Up-to-date methodology for a fast moving field Designed with the needs of both basic scientists and clinicians in mind Authors are leaders in their respective fields

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Leslie Wilson, Paul T. Matsudaira, Lawrence M. Schwartz, Jonathan D. Ashwell

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A Guide to Starting Psychotherapy Groups

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How does a therapist go about starting a psychotherapy group? In this practical guide the reader finds the elements, both attitudinal and procedural, needed for starting a therapy group. The processes of obtaining referrals, selecting clients, orienting and educating clients, and preparing clients for psychotherapy are covered in clear step-by-step procedures. Tables and charts are provided for the necessary record keeping. The initial chapters detail the important stages leading up to the first therapy session. Eminent group therapists present special chapters on various therapeutic approaches. The topics of terminating groups and the role of the therapist close this pragmatic guide to therapy groups.

A Guide to Starting Psychotherapy Groups assists psychologists, social workers, psychiatrists, nurse clinicians, pastoral counselors, school and college counselors and other trained therapists in the process of forming and maintaining groups.
Steps for getting groups started, beginning with first mention of group therapy to clients Clarification of differing theoretical approaches to doing groups Helpful guides for tracking referrals and billing Analysis of group psychotherapy's effectiveness Attention to special groups and co-therapy leadership Authoritative articles by international leaders in group psychotherapy

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John R. Price, David R. Hescheles, A. Rae Price

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Amyloid, Prions, and Other Protein Aggregates

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This volume includes a core of methodologies to attack the unique experimental problems presented by protein misassembly. Emphasis is on human biology applications, the area in which there is the most interest, in which most of the work has already been done, and in which there is the best evidence for the structural sophisitication of the protein aggregates.The critically acclaimed laboratory standard for more than forty years, Methods in Enzymology is one of the most highly respected publications in the field of biochemistry. Since 1955, each volume has been eagerly awaited, frequently consulted, and praised by researchers and reviewers alike. Now with more than 300 volumes (all of them still in print), the series contains much material still relevant today--truly an essential publication for researchers in all fields of life sciences.

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John N. Abelson, Melvin I. Simon, Ronald Wetzel

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Carbon Isotope Techniques is a hands-on introduction to using carbon isotope tracers in experimental biology and ecology. It provides an easy bench-top reference with many simple-to-follow protocols for studying plants, animals, and soils. The 11C, 12C, 13C, and 14C carbon isotopes are considered and standard techniques are described by established authors. This is a synthetic compilation of well-established techniques.<br>Researchers and students in a wide range of disciplines spanning plant and soil science, agricultural chemistry, forestry, ecology, oceanography, limnology, biogeochemistry, anthropology, and archaeology will find Carbon Isotope Techniques a valuable resource. Features isotopes in ecological research Highlights specific user-oriented techniques Considers carbon cycle in plants, soils, animals, air, and water Provides examples and sample calculations for radioisotopes in plant, soil, and aquatic biology

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Eldor Paul, Jerry Melillo, David C. Coleman, Brian Fry

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Blood substitutes are solutions designed for use in patients who need blood transfusions, but for whom whole blood is not available, or is not safe. This interest has intensified in the wake of the AIDS and hepatitis C epidemics. Blood Substitutes describes the rationale, current approaches, clinical efficacy, and design issues for all blood substitutes now in clinical trials. The many summary diagrams and tables help make the book accessible to readers such as surgeons and blood bankers, who have less technical expertise than the biochemists and hematologists who are designing and testing blood substitutes.

* Includes chapters necessary to the understanding of blood substitutes, including history, toxicity, physiology, and clinical applications* Presents detailed descriptions of the various products that have been developed and have advanced to clinical trials, and some that are in earlier states of development

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Recent advances in understanding the biological role of singlet oxygen in the pathways of cellular responses to ultraviolet-A radiation: its key position in photodynamical effects, and its generation by photochemical (dark) reactions, e.g. by cells of the immune system such as eosinophils and macrophages, are the focus of this volume. The new methods and techniques responsible for the rapid progress in this area are presented.

The critically acclaimed laboratory standard for more than forty years, Methods in Enzymology is one of the most highly respected publications in the field of biochemistry. Since 1955, each volume has been eagerly awaited, frequently consulted, and praised by researchers and reviewers alike. Now with more than 300 volumes (all of them still in print), the series contains much material still relevant today--truly an essential publication for researchers in all fields of life sciences.

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John N. Abelson, Melvin I. Simon, Lester Packer, Helmut Sies

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International Review of Cytology presents current advances and comprehensive reviews in cell biology, both plant and animal. Articles address structure and control of gene expression, nucleocytoplasmic interactions, control of cell development and differentiation, and cell transformation and growth. Authored by some of the foremost scientists in the field, each volume provides up-to-date information and directions for future research.This volume brings together current information on the localization and roles of RNAs in cell-lineage determination and subsequent patterning in embryonic development. Guest co-editor Lawrence Etkin is one of the leading researchers in molecular genetics of Xenopus.

Key Features* A number of important concepts are discussed, including:* How polarity is established during oogenesis* How germ cell determinants become organized in the establishment of the germ cell lineage* Different strategies used by organisms to establish the germ cell lineage* Similarities and differences between the mechanisms used in embryonic patterning* The mechanisms and machinery by which molecules such as RNA become asymmetrically segregated* The use of similar signaling pathways in patterning of the dorsal-ventral and right-left asymmetries, embryonic germ layers, limb, and nervous system* The link between fundamental biological processes such as RNA translation and localization in the regulation of axis specification

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Paroxysmal Nocturnal Hemoglobinuria (PNH) has been recognized for over a century. This mysterious disease is now understood at the level of the gene and the protein. The pathophysiology is related to a class of cell surface proteins with distinctive biochemical and physical characteristics. Recently it has been acknowledged that PNH is not rare, and once sensitive assays--based on the chemistry of the proteins--can be applied to many patients.
Written by international experts in the field, this book includes a number of distinctive characteristics, such as the clinical features of PNH, the mechanism of hemolysis, the biochemistry of glycosylphosphoinositol anchors, and the chemistry and biophysics of GPI-anchored proteins.
This unique and timely volume will have a wide audience, including hematologists and oncologists with a clinical interest in this disease, as well as basic biochemists, immunologists, and cell biologists studying this class of proteins. Outlines the chemical features of PNH Explains the mechanism of hemolysis Includes work on the biochemistry of glycophosphoinositol anchors Contains descriptions of the chemistry and biophysics of GPI-anchored proteins

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This treatment guide is based on selected disorders taken from the American Psychiatric Association DSM-IV Diagnostic Classifications. The disorders selected are treatable or responsive to brief therapy methods.<br>The therapist or student in training can use this book to identify the elements needed for formulating a treatment plan on disorders typically encountered in clinical practice. The approaches taken are based on cognitive behavioral principles and makes use of empirical findings. However, the case study format allows the reader to see how the assessment and treatment is implemented in a "real-life" patient, and not as a clinical abstraction distilled from research studies. Moreover, the treatment plan is outlined in a manner that makes reimbursement likely from managed care organizations and insurance companies. Effective Brief Therapies is useful as a reference for therapists and as a training guide for graduate students. Case Descriptions Treatment Conceptualization Assessment Techniques Treatment Implementation Techniques Concurrent Diagnoses and Treatment Complications and Treatment Implications Dealing with Managed Care and Accountability Outcome and Follow-up Dealing with Recidivism

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The Primer on the Autonomic Nervous System presents, in a readable and accessible format, key information about how the autonomic nervous system controls the body, particularly in response to stress. It represents the largest collection of world-wide autonomic nervous system authorities ever assembled in one book. It is especially suitable for students, scientists and physicians seeking key information about all aspects of autonomic physiology and pathology in one convenient source. Providing up-to-date knowledge about basic and clinical autonomic neuroscience in a format designed to make learning easy and fun, this book is a must-have for any neuroscientists bookshelf! Greatly amplified and updated from previous edition including the latest developments in the field of autonomic cardiovascular regulation and neuroscience Provides key information about all aspects of autonomic physiology and pathology Discusses stress and how its effects on the body are mediated Compiles contributions by over 140 experts on the autonomic nervous system

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Volume 324 of Methods in Enzymology supplements Volume 166. It includes genetic information (cloning, gene expression) and information on human genetic diseases not available when Volume 166 was published.General Description of the Series:The critically acclaimed laboratory standard for more than forty years, Methods in Enzymology is one of the most highly respected publications in the field of biochemistry. Since 1955, each volume has been eagerly awaited, frequently consulted, and praised by researchers and reviewers alike. Now with more than 300 volumes (all of them still in print), the series contains much material still relevant today--truly an essential publication for researchers in all fields of life sciences. Preparation of substrates and assay of enzymes Cloning, expression, and purification of enzymes Detection and consequences of genetic defects Regulation and expression of enzymes

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John N. Abelson, Melvin I. Simon, John R. Sokatch, Robert Adron Harris

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International Handbook of Earthquake & Engineering Seismology, Part A

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Modern scientific investigations of earthquakes began in the 1880s, and the International Association of Seismology was organized in 1901 to promote collaboration of scientists and engineers in studying earthquakes. The International Handbook of Earthquake and Engineering Seismology, under the auspices of the International Association of Seismology and Physics of the Earth's Interior (IASPEI), was prepared by leading experts under a distinguished international advisory board and team of editors.The content is organized into 56 chapters and includes over 430 figures, 24 of which are in color.

This large-format, comprehensive reference summarizes well-established facts, reviews relevant theories, surveys useful methods and techniques, and documents and archives basic seismic data. It will be the authoritative reference for scientists and engineers and a quick and handy reference for seismologists.Also available is The International Handbook of Earthquake and Engineering Seismology, Part B.

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William H.K. Lee, Paul Jennings, Carl Kisslinger, Hiroo Kanamori

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Paleomagnetism is the study of the fossil magnetism in rocks. It has been paramount in determining that the continents have drifted over the surface of the Earth throughout geological time. The fossil magnetism preserved in the ocean floor has demonstrated how continental drift takes place through the process of sea-floor spreading. The methods and techniques used in paleomagnetic studies of continental rocks and of the ocean floor are described and then applied to determining horizontal movements of the Earth's crust over geological time. An up-to-date review of global paleomagnetic data enables 1000 million years of Earth history to be summarized in terms of the drift of the major crustal blocks over the surface of the Earth.

The first edition of McElhinny's book was heralded as a "classic and definitive text." It thoroughly discussed the theory of geomagnetism, the geologic reversals of the Earth's magnetic field, and the shifting of magnetic poles. In the 25 years since the highly successful first edition of Palaeomagnetism and Plate Tectonics (Cambridge, 1973) the many advances in the concepts, methodology, and insights into paleomagnetism warrant this new treatment. This completely updated and revised edition of Paleomagnetism: Continents and Oceans will be a welcome resource for a broad audience of earth scientists as well as laypeople curious about magnetism, paleogeography, geology, and plate tectonics.

Because the book is intended for a wide audience of geologists, geophysicists, and oceanographers, it balances the mathematical and descriptive aspects of each topic.
Details the theory and methodology of rock magnetism, with particular emphasis on intrepreting crustal movements from continental and oceanic measurements Outlines Earth history for the past 1000 million years, from the Rodinia super-continent through its breakup and the formation of Gondwana to the formation and breakup of Pangea and the amalgamation of Eurasia Provides a comprehensive treatment of oceanic paleomagnetism Provides a set of color pateogeographic maps covering the past 250 million years Written by two internationally recognized experts in the field

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Michael W. McElhinny, Phillip L. McFadden, Renata Dmowska, James R. Holton, H. Thomas Rossby

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Gene transfer within humans has been an obstacle until about 10 years ago. At that time, it was found that viral vectors were effective carriers of "healthy genes" into patients' cells. The problem, however, was that viral vectors proved unnecessarily harmful to humans: subjects experienced inflamatory activity and negative immunological responses to the genes. Viral vectors were also unable to meet the needs of the pharmaceutical community: they were not reproducible in large-scale proportions in cost-effective ways.
Thus, research was undertaken to find a safer way to transfer genes to patients without jeopardizing the safety of the patient. And so non-viral vectors were discovered. This volume presents the various non-viral vectors currently under development. Although not methodologically oriented, it will provide the necessary details behind the development of the vectors. This information will prove useful to both researchers and clinicians.

Key Features
* Presents state-of-the art developments of nonviral vectors as tools for modern molecular medicine
* Covers all types of nonviral vectors, from molecular structure to therapeutic application
Provides a comprehensive review of synthetic vectors
* Includes contributions from major investigators and leading experts in the field

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Mien-Chie Hung, Leaf Huang, Ernst Wagner

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Carbon Dioxide, Populations, and Communities

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In past decades and in association with a continuing global industrial development, the global atmospheric concentration of carbon dioxide has been rising. Among the many predictions made concerning this disturbing trend is global warming sufficient to melt polar ice-caps thereby dramatically altering existing shorelines. This book will help fill an obvious gap in the carbon dioxide debate by substituting date for speculation.

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* Includes contributions from leading authorities around the world
* Serves as a companion to Carbon Dioxide and Terrestrial Ecosystems
* The first book of its kind to explore evolutionary responses of both populations and communities to elevated carbon dioxide

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Sea Level Rise, History and Consequences includes a special emphasis on the evidence for historical sea level change; case studies are used to demonstrate the resulting consequences. A CD-ROM is included which contain tide gauge data and trends of relative sea level from the Permanent Service for Mean Sea Level. The material on the CD-ROM is either in the form of text files, or web sites that can be opened by widely available web-browsers.

Sea level is expected to rise as much as 60-100 centimeters over the next century due to greenhouse-induced global warming -- or at least that is what the some scientists predict. However, the concept of sea level is extremely complex, which makes the prediction of sea level rise anything but certain. The reviewers are in consensus in enthusiastically endorsing this comprehensive book and CD-ROM treatment.

This book will be a comprehensive review of the subject using the data themselves (on CD-ROM) to illustrate the principles involved, rather than detailed mathematical treatments. The book should be readily accessible to upper division and first-year graduate students in the environmental sciences, geography, geology, and other interdisciplinary fields. Four pages (up to 16 pages) of color in the printed text.

The book will have wide appeal. It will be read by geologists, geophysicists, climatologists, oceanographers, meteorologists, environmental scientists, geomorphologists, coastal engineers, and policy makers in all of these fields.

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Bruce Douglas, Mark T Kearney, Stephen P. Leatherman

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Carbon Dioxide and Terrestrial Ecosystems

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The importance of carbon dioxide extends from cellular to global levels of organization and potential ecological deterioration may be the result of increased CO2 in our atmosphere. Recently, the research emphasis shifted from studies of photosynthesis pathways and plant growth to ground-breaking studies of carbon dioxide balances in ecosystems, regions, and even the entire globe.

Carbon Dioxide and Terrestrial Ecosystems addresses these new areas of research. Economically important woody ecosystems are emphasized because they have substantial influence on global carbon dioxide balances. Herbaceous ecosystems (e.g., grasslands, prairies, wetlands) and crop ecosystems are also covered. The interactions among organisms, communities, and ecosystems are modeled, and the book closes with an important synthesis of this growing nexus of research.

Carbon Dioxide and Terrestrial Ecosystems is a compilation of detailed scientific studies that reveal how ecosystems generally, and particular plants specifically, respond to changed levels of carbon dioxide.
Contributions from an international team of experts Empirical examination of the actual effects of carbon dioxide Variety of terrestrial habitats investigated Specific plants and whole ecosystems offered as studies

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The second edition of Mesoscale Meteorological Modeling is a fully revised resource for researchers and practitioners in the growing field of meteorological modeling at the mesoscale. Pielke has enhanced the new edition by quantifying model capability (uncertainty) by a detailed evaluation of the assumptions of parameterization and error propagation. Mesoscale models are applied in a wide variety of studies, including weather prediction, regional and local climate assessments, and air pollution investigations.