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Hot Spot Pollutants describes how pharmaceuticals and/or endocrine active compounds gain entry into the aquatic ecosystem, effects on specific organisms and the potential risk involved for the whole ecosystem. In addition it presents the latest views and developments regarding legal requirements for assessing the environmental risk of pharmaceuticals. This books includes the views of academic, industry and government scientists, and thus aims for a balanced presentation of all standpoints.
The book consists of papers that appeared previously in the journal Toxicology Letters in 2002 and 2003, and have been collected in this single volume to make them accessible to a broader audience. Authors were asked to update their contributions where necessary. See also Toxicology Letters volume 131, issues 1 and 2 (2002), and volume 142 issue 3 (2003).

* State-of-the-art information of pharmaceuticals in the environment
* Leading Academic, industry and government contributors
* Provides the views of the experts in the field
* Offers a thorough basis to attain a good overview including all facets of the field

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Daniel R. Dietrich, Simon Webb, Thomas Petry

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Geometric Morphometrics for Biologists is an introductory textbook for a course on geometric morphometrics, written for graduate students and upper division undergraduates, covering both theory of shape analysis and methods of multivariate analysis. It is designed for students with minimal math background; taking them from the process of data collection through basic and more advanced statistical analyses. Many examples are given, beginning with simple although realistic case-studies, through examples of complex analyses requiring several different kinds of methods. The book also includes URLs for free software and step-by-step instructions for using the software.

* Accessible, student-tested introduction to sophisticated methods of biological shape analysis
* Detailed instructions for conducting analyses with freely available, easy to use software
* Numerous illustrations; including graphical presentations of important theoretical concepts and demonstrations of alternative approaches to presenting results
* Many realistic examples, both simple and complex, from on-going research
* Comprehensive glossary of technical terms

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Miriam Zelditch, Donald Swiderski, H. David Sheets, William L. Fink

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This volume presents work from six different groups working on various aspects of cycloaddition chemistry. Jose Mascarenas gives us a very interesting account of the chemistry of &Bgr;-alkoxy-&ggr;-pyrones and related species. Al Padwa and Chris Staub discuss further advances in rhodium carbenoid chemistry and the unusual cycloaddition processes possible with these intermediates. Higher order cycloadditions mediated by transition metals highlight Jim Rigby's update on his group's efforts in this area. Lily Lee and John Snyder present us with a detailed account of the indole ring as a dienophile, challenging us to consider the untapped potential in this area. Brian Keay and Ian Hunt discuss the intramolecular Diels-Alder reactions of furan; a report that is both top-notch science, and what could be a great learning tool for students who need to see how fundamental chemical principles can and should be applied to synthetic problems. Finally, Kay Brummond introduces us to a new version of the Pauson-Khand reactions, one that will no doubt be further exploited in productive ways by her group well into the future.

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PET and SPECT are two of todays most important medical-imaging methods, providing images that reveal subtle information about physiological processes in humans and animals. Emission Tomography: The Fundamentals of PET and SPECT explains the physics and engineering principles of these important functional-imaging methods. The technology of emission tomography is covered in detail, including historical origins, scientific and mathematical foundations, imaging systems and their components, image reconstruction and analysis, simulation techniques, and clinical and laboratory applications. The book describes the state of the art of emission tomography, including all facets of conventional SPECT and PET, as well as contemporary topics such as iterative image reconstruction, small-animal imaging, and PET/CT systems. This book is intended as a textbook and reference resource for graduate students, researchers, medical physicists, biomedical engineers, and professional engineers and physicists in the medical-imaging industry. Thorough tutorials of fundamental and advanced topics are presented by dozens of the leading researchers in PET and SPECT. SPECT has long been a mainstay of clinical imaging, and PET is now one of the worlds fastest growing medical imaging techniques, owing to its dramatic contributions to cancer imaging and other applications. Emission Tomography: The Fundamentals of PET and SPECT is an essential resource for understanding the technology of SPECT and PET, the most widely used forms of molecular imaging.

*Contains thorough tutorial treatments, coupled with coverage of advanced topics
*Three of the four holders of the prestigious Institute of Electrical and Electronics Engineers Medical Imaging Scientist Award are chapter contributors
*Include color artwork

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Adaptation to Built and Cultivated Environments

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This book is a collection of papers highlighting ways in which Raptors have successfully adapted to man-made landscapes and structures. The coverage of Raptors in Human Landscapes is broad, ranging from the impact of human activity on country-wide scales to the particular conditions associated with urban, cultivated, and industrial landscapes, as well as to the various schemes specifically directed towards the provision of artificial nest sites and platforms. The cases described hail from a wide geographic range including North and South America, Europe, Africa and elsewhere, and from a broad spectrum of species groups such as the falcons, accipiters, eagles, kites, and many others.This is a book of immense value not only to ornithologists and conservation biologists, but also to engineers and managers involved in all kinds of building and environmental work in cities, power and water works, agriculture, and forestry. Serves as a good introduction to all aspects of the subject Focuses on successful adaptations of Raptors to environmental change

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David M. Bird, Daniel E. Varland, Juan Jose Negro

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Advances in Applied Microbiology offers intensive reviews of the latest techniques and discoveries in this rapidly moving field. The editors are recognized experts and the format is comprehensive and instructive.

This volume contains 12 comprehensive reviews, including: Uses of Trichoderma spp. to alleviate or remediate soil and water pollution; Lincosamides, chemical structure, biosynthesis, mechanism of action, resistance and applications; Polysaccharide breakdown by anaerobic microogranisms inhabiting the mammalian gut; and Novel aspects of signaling in Streptomyces development.

* This series has been in constant publication since 1959
* An ISI impact factor of 1.0 in 2002
* This volume contains 12 comprehensive reviews of current research in applied microbiology

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Allen I. Laskin, Joan W. Bennett, Geoffrey M. Gadd

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Freshwater algae are among the most diverse and ubiquitous organisms on earth. They occupy an enormous range of ecological conditions from lakes and rivers to acidic peat swamps, inland saline lakes, snow and ice, damp soils, wetlands, desert soils, wastewater treatment plants, and are symbionts in and on many plants, fungi, and animals. In North America, the variety of freshwater habitats colonized by algae is very rich, and offers an enormous and fascinating range of environments for their study. They form the base of most aquatic food webs and are critical to studies of ecosystem health. Algal ecologists and taxonomists play an important role in the understanding of aquatic ecosystems: their biodiversity, productivity, interactions with other organisms, and water quality. This book provides in one volume a practical and comprehensive guide to the genera of freshwater algae known from North America. The format combines the necessary ecological, taxonomic and methodological information for all scientists working in aquatic environments, whether their specialty is in environmental monitoring and water quality assessment, biological composition, ecology, evolution, or molecular biology.

Key Features
* The first complete accounting of North America's freshwater algal genera in more than 50 years
* Includes a guide to the current literature on species identification in each group of algae
* High-quality photographs and drawings of more than 770 genera
* A clear, easy-to-use introductory key to the diagnostic chapters
* Synthetic chapters on freshwater habitats, use of algae in environmental assessment, and control of nuisance algae
* Contributions from 27 experts in all areas of freshwater algae
* Extensive literature citations
* Companion volume of Ecology and Classification of North American Freshwater Invertebrates 2nd edition, edited by Throp and Covich

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John D. Wehr, Robert G. Sheath, J. Patrick Kociolek, James H. Thorp

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The development and application of cycloaddition methodology continues to be at the forefront of research in synthetic organic chemistry. This volume begins with a review of methods available for the synthesis of seven-membered rings and is followed with work on metal-catalyzed cycloadditions.  There is then an update on the cycloaddition chemistry of 2-pyrone, and then a unique application of photocycloaddition is detailed.  The final chapter is a discussion of the latest explorations of the reaction of rhodium-stabilized vinyl carbenoids with dienes.

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This volume covers all aspects of embryonic stem cell differentiation, including mouse embryonic stem cells, mouse embryonic germ cells, monkey and human embryonic stem cells, and gene discovery.

* Early commitment steps and generation of chimeric mice* Differentiation to mesoderm derivatives* Gene discovery by manipulation of mouse embryonic stem cells

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Imagine trying to understand an engine without visualizing its moving parts. Biological processes involve far more complex chemical reactions and components than any engine. Furthermore, the parts work together to do many more functions than an engine which sole task is to turn a shaft. Understanding the implications of the three-dimensional coordinates for a molecule with several thousand atoms requires an understanding of, and practice with, 3D imaging. For many biologists, this means acquiring a whole new set of skills. Foundations of Structural Biology is aimed at helping the reader develop visualization skills for protein or DNA segments, while also describing the fundamental principles underlying the organization and interaction between these complex molecules.

Key Features* Explains how to use coordinate databases and atomic coordinates of biological macromolecules* Teaches the skills of stereoviewing* Contains computer-generated stereographics* Describes the principles of symmetry and handedness in proteins and DNA* Introduces metal and lipid binding proteins and DNA-protein interactions* Explains the principles involved in understanding secondary and quaternary structure * Includes coverage of protein-metal, protein-nucleic acid, and protein-lipid interactions

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This series describes selected advances in the area of atomic spectroscopy. It is promarily intended for the reader who has a background in atmoic spectroscopy; suitable to the novice and expert. Although a widely used and accepted method for metal and non-metal analysis in a variety of complex samples, Advances in Atomic Spectroscopy covers a wide range of materials. Each Chapter will completely cover an area of atomic spectroscopy where rapid development  has occurred.

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Laboratory Experiments in the Social Sciences

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Laboratory Experiments in the Social Sciences is the only book providing core information for researchers about the ways and means to conduct experiments. Its comprehensive regard for laboratory experiments encompasses how-to explanations, investigations of philosophies and ethics, explorations of experiments in specific social science disciplines, and summaries of both the history and future of social science laboratories. No other book offers such a direct avenue to enlarging our knowledge in the social sciences.This collection of original chapters combines instructions and advice about the design of laboratory experiments in the social sciences with the array of other issues. While there are books on experimental design and chapters in more general methods books on design, theory, and ethical issues, no other book attempts to discuss the fundamental ideas of the philosophy of science or lays out the methods comprehensively or in such detail. Experimentation has recently prospered because of increasing interest in cross-disciplinary syntheses, and this book of advice, guidelines, and observations underline its potential and increasing importance.

Provides a comprehensive summary of issues in social science experimentation, from ethics to design, management, and financing Offers "how-to" explanations of the problems and challenges faced by everyone involved in social science experiments Pays attention to both practical problems and to theoretical and philosophical arguments Defines commonalities and distinctions within and among experimental situations across the social sciences

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The Encyclopedia of Insects is a comprehensive work devoted to all aspects of insects, including their anatomy, physiology, evolution, behavior, reproduction, ecology, and disease, as well as issues of exploitation, conservation, and management. Articles provide definitive facts about all insects from aphids, beetles and butterflies to weevils and yellowjackets.

Insects are beautiful and dreadful, ravenous pests and devastating disease vectors, resilient and resistant to eradication, and the source of great benefit and great loss for civilization. Important for ecosystem health, they have influenced the evolution of other life forms on our planet including humans. Anyone interested in insects, from university professors and researchers to high school students preparing a report, will find The Encyclopedia of Insects an indispensable volume for insect information.

* An unprecedented collection in 1,276 pages covering every important aspect of insects
* Presents 270 original articles, thoroughly peer reviewed and edited for consistency
* Features 1,000 figures and tables, including 500 full-color photographs
* Includes the latest information contributed by 250 experts in 17 countries
* Designed to save research time with a full glossary, 1,700 cross-references, and 3,000 bibliographic entries

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Why a book on molecular neurology? Molecular neuroscience is advancing at a spectacular rate. As it does so, it is revealing important clues to the pathogenesis and pathophysiology of neurological diseases, and to the therapeutic targets that they present. Medicines work by targeting molecules. The more specific the targeting, the more specific the actions, and the fewer the side effects. Molecular Neurology highlights, for graduate and MD-PhD students, research fellows and research-oriented clinical fellows, and researchers in the neurosciences and other biomedical sciences, the principles underlying molecular medicine as related to neurology. Written by internationally recognized experts, this well-illustrated and well-referenced book presents the most up-to-date principles and disease examples relevant to molecular neurology, and reviews the concepts, strategies, and latest progress in this field. This book will interest anyone studying the molecular basis of neurology, or developing new therapies in neurology. Describes the newest molecular aspects of neurological disorders Provides an introduction to neurological disorders for basic scientists Updates clinicians and clinical researchers on the most recent developments

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Richard A. Settersten Jr., Timothy J Owens

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This updated second edition of the popular methods book "Video Microscopy" shows how to track dynamic changes in the structure or architecture of living cells and in reconstituted preparations using video and digital imaging microscopy.  Contains 10 new chapters addressing developments over the last several years.  Basic information, principles, applications, and equipment are covered in the first half of the volume and more spcialized video microscopy techniques are covered in the second half. Shows how to track dynamic changes in the structure or architecture of living cells and in reconstituted preparations using video and digital imaging microscopy Contains 10 new chapters addressing developments over the last several years Covers basic principles, applications, and equipment Spcialized video microscopy techniques are covered

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Knowledge of plant names can give insight into largely forgotten beliefs. For example, the common red poppy is known as "Blind Man" due to an old superstitious belief that if the poppy were put to the eyes it would cause blindness. Many plant names derived from superstition, folk lore, or primal beliefs. Other names are purely descriptive and can serve to explain the meaning of the botanical name. For example, Beauty-Berry is the name given to the American shrub that belongs to the genus Callicarpa. Callicarpa is Greek for beautiful fruit. Still other names come from literary sources providing rich detail of the transmission of words through the ages.Conceived as part of the author's wider interest in plant and tree lore and ethnobotanical studies, this fully revised edition of Elsevier's Dictionary of Plant Names and Their Origins contains over 30,000 vernacular and literary English names of plants. Wild and cultivated plants alike are identified by the botanical name. Further detail provides a brief account of the meaning of the name and detailed commentary on common usage.

* Includes color images * Inclusive of all Latin terms with vernacular derivatives * The most comprehensive guide for plant scientists, linguists, botanists, and historians

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Inflammation, Nutrition, and Aging in the Evolution of Lifespans

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Written by Caleb Finch, one of the leading scientists of our time, The Biology of Human Longevity: Inflammation, Nutrition, and Aging in the Evolution of Lifespans synthesizes several decades of top research on the topic of human aging and longevity particularly on the recent theories of inflammation and its effects on human health. The book expands a number of existing major theories, including the Barker theory of fetal origins of adult disease to consider the role of inflammation and Harmon's free radical theory of aging to include inflammatory damage. Future increases in lifespan are challenged by the obesity epidemic and spreading global infections which may reverse the gains made in lowering inflammatory exposure. This timely and topical book will be of interest to anyone studying aging from any scientific angle. Author Caleb Finch is a highly influential and respected scientist, ranked in the top half of the 1% most cited scientists Provides a novel synthesis of existing ideas about the biology of longevity and aging Incorporates important research findings from several disciplines, including Gerontology, Genomics, Neuroscience, Immunology, Nutrition

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Cellular and Molecular Neurobiology (Deluxe Edition)

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This Second Edition is the new, thoroughly revised edition of the established and well-respected authoritative text in the field. Cellular and Molecular Neurobiology is hypothesis-driven and firmly based on numerous experiments performed by experts in the field. Seven new chapters (five new and two totally rewritten) complement and expand on the First Edition and are written in a way that encourages students to ask questions. Additionally, new, groundbreaking research data on dendritic processing is presented in a very easy-to-understand format.

Key Features:* Ionic basis of neuronal excitability* Synaptic transmission and sensory transduction* Dentritic rocessing of afferent information* Activity and development of neuronal network

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Advances in Immunology, a long established and highly respected serial, presents current developments as well as comprehensive reviews in immunology. Articles address the wide range of topics that comprise immunology, including molecular and cellular activation mechanisms, phylogeny and molecular evolution, and clinical modalities. Edited and authored by the foremost scientists in the field, each volume provides up-to-date information and directions for future research.