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Bacterial Pathogenesis, Part C: Identification, Regulation and Function of Virulence Factors

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The critically acclaimed laboratory standard for more than forty years, Methods in Enzymology is one of the most highly respected publications in the field of biochemistry. Since 1955, each volume has been eagerly awaited, frequently consulted, and praised by researchers and reviewers alike. Now with more than 300 volumes (all of them still in print), the series contains much material still relevant todaytruly an essential publication for researchers in all fields of life sciences.

Key Features
* Presents alternatives to mammalian model systems
* Discusses virulence and essential gene identification
* Defines global gene expression

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International Review of Cytology presents current advances and comprehensive reviews in cell biology--both plant and animal. Articles in this volume address topics such as GABA and GABA receptors in CNS and other organs, neuroendocrine control of pheromone biosynthesis in moths, gene transfer to salivary glands, cell type-specificexpression of secretory TFF-peptides in the brain, molecular patterning along the sea urchin animal-vegetal axis, and cell and molecular cell biology of melanin-concentrating hormone. Authored by some of the foremost scientists in the field, each volume provides up-to-date information and directions for future research.

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Advances in Immunology presents current developments as well as comprehensive reviews in immunology. Articles address the wide range of topics that comprise immunology, including molecular and cellular activation mechanisms, phylogeny and molecular evolution, and clinical modalities. Edited and authored by the foremost scientists in the field, each volume provides up-to-date information and directions for future research.

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International Review of Cytology presents current advances and comprehensive reviews in cell biology--both plant and animal. Articles in this volume address topics such as class A macrophage scavenger receptors, microtubule transport in the axon, G-protein-coupled receptors, genes involved in the initiation of DNA replication in yeast, phenotype switching in polymorphic tetrahymena, and mitosis and motor proteins. Authored by some of the foremost scientists in the field, each volume provides up-to-date information and directions for future research.

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International Review of Cytology presents current advances and comprehensive reviews in cell biology--both plant and animal. Articles in this volume address such topics as cytoskeleton-dependent transport and localization of nRNA, special cytochemistry in cell biology, plasticity and stabilization of neuromuscular and CNS synapses, adipokinetic hormones of insects, and iron metabolism in mammalian cells. Authored by some of the foremost scientists in the field, each volume provides up-to-date information and directions for future research.

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International Review of Cytology presents current advances and comprehensive reviews in cell biology--both plant and animal. Articles address structure and control of gene expression, nucleocytoplasmic interactions, control of cell development and differentiation, and cell transformation and growth. Authored by some of the foremost scientists in the field, each volume provides up-to-date information and directions for future research.

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The Advances in Cancer Research series provides invaluable information on the exciting and fast-moving field of cancer research. This volume presents outstanding and original reviews on a variety of topics, including gene expression in inherited breast cancer, multiparameter analyses of cell cycle regulation in tumorigenesis, Rho GTPases in transformation and metastasis, the myc oncogene, genetic requirements for the episomal maintenance of oncogenic herpesvirus genomes, treatment of Epstein-Barr virus-associated malignancies with specific T cells, the role of glycogen synthase kinase-3 in cancer, chronic immune activation and inflammation in the pathogenesis of AIDS and cancer, and molecular biology of Hodgkin's lymphoma. Gene Expression in Inherited Breast Cancer Multiparameter Analyses of Cell Cycle Regulatory Proteins in Human Breast Cancer: A Key to Definition of Separate Pathways in Tumorigenesis Rho GTPases in Transformation and Metastasis The myc Oncogene: Marvelously Complex Genetic Requirements for the Episomal Maintenance of Oncogenic Herpevirus Genomes Treatment of Epstein-Barr Virus-Associated Malignancies with Specific T Cells Role of Glycogen Synthase Kinase-3 in Cancer: Regulation Wnts and Other Signaling Pathways Chronic Immune Activation and Inflammation in the Pathogenesis of AIDS and Cancer Molecular Biology of Hodgkin's Lymphoma

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The content of this volume is designed to reach a wide audience, including those involved with relevant technologies such as electrophoresis and mass spectrometry, to those interested in how proteomics can benefit research. A wide range of techniques are discussed, each specifically designed to address different needs in proteomic analysis. The concluding chapter discusses the important issue related to handling large amounts of data accumulated in proteomic studies. Discusses proteomics in the postgenomic age Includes various strategies for quantitative proteomics Covers the role of MS in structural functional proteomics and proteomics in drug discovery and bioinformatics

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Advances in Botanical Research is a multi-volume publication that brings together reviews by recognized experts on subjects of importance to those involved in botanical research. First published in 1963, Advances in Botanical Research has earned a reputation for excellence in the field for more than thirty years. In 1995, Advances in Botanical Research was merged with Advances in Plant Pathology to provide one comprehensive resource for the plant science community, with equal coverage of plant pathology and botany in both thematic and mixed volumes. Now edited by J.A. Callow (University of Birmingham, UK), supported by an international Editorial Board, Advances in Botanical Research publishes in-depth and up-to-date reviews on a wide range of topics which will appeal to post-graduates and researchers in plant sciences including botany, plant biochemistry, plant pathology and plant physiology. Eclectic volumes in the serial are supplemented by thematic volumes on such topics as Plant Protein Kinases, and Plant Trichomes.In 1999, the Institute for Scientific Information released figures showing that Advances in Botanical Research has an Impact Factor of 4.378, placing it 8th in the highly competitive category of Plant Sciences.

* Features a wide range of scientific perspectives* Written by internationally recognized authorities at the leading edge of the relevant science* For over 30 years, series has enjoyed a reputation for excellence

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The Advances in Cancer Research series provides invaluable information on the exciting and fast-moving field of cancer research. This volume presents outstanding and original reviews on a variety of topics including Central Roles of Mg2+ and MgATP2- in the Regulation of Protein Synthesis and Cell Proliferation: Significance for Neoplastic Transformation; Presence and Influence of Human Papillomaviruses (HPV) in Tonsillar Cancer; T-Cell Transformation and Oncogenesis by a2-Herpesviruses; Chaperoning Antigen Presentation by MHC Class II Molecules and Their Role in Oncogenesis; Soluble Mediators of Inflammation During Tumor Development; Classical and Non-Classical HLA Class I Antigen and NK Cell Activating Ligand Changes in Malignant Cells:  Current Challenges and Future Directions.

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Advances in Food and Nutrition Research recognizes the integral relationship between the food and nutritional sciences and brings together outstanding and comprehensive reviews that highlight this relationship.

Contributions detail the scientific developments in the broad areas of food science and nutrition are intended to ensure that food scientists in academia and industry as well as professional nutritionists and dieticians are kept informed concerning emerging research and developments in these important disciplines.

Chapters cover biosensors and bio-based methods for the separation and detection of foodborne pathogens, the immunological components of human milk, PCR-based diagnosis and quantification of mycotoxin-producing fungi, molluscan shellfish allergy, nutritargeting, and a review of the supporting science behind the health benefits of calcium citrate malate.
Series established since 1948 Advisory Board consists of 8 respected scientists Unique series as it combines food science and nutrition research

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Lipidomics and Bioactive Lipids: Specialized Analytical Methods and Lipids in Disease

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This volume in the well-established Methods in Enzymology series features methods for the study of lipids using mass spectrometry techniques. Articles in this volume cover topics such as Liquid chromatography mass spectrometry for quantifying plasma lysophospholipids: potential biomarkers for cancer diagnosis; Measurement of eicosanoids in cancer tissues; Noninvasive Assessment of the Role of Cyclooxygenases in Cardiovascular HealthA Detailed HPLC/MS/MS Method; Lipidomics in Diabetes and the Metabolic Syndrome; LC-MS-MS Analysis of Neutral Eicosanoids; Quantification Of F2-Isoprostanes In Biological Fluids And Tissues As A Measure Of Oxidant Stress; Measurement of Products of Docosahexaenoic Acid Peroxidation, Neuroprostanes, and Neurofurans; Enantiomeric separation of hydroxy and hydroperoxy eicosanoids by chiral column chromatography; Targeted Chiral Lipidomics Analysis by Liquid Chromatography Electron Capture Atmospheric Pressure Chemical Ionization Mass Spectrometry (LC-ECAPCI/MS); Shotgun Lipidomics by Tandem Mass Spectrometry under Data-Dependent Acquisition Control; Identification of Intact Lipid Peroxides by Ag+ Coordination Ionspray Mass Spectrometry (CIS-MS); Quantification of Cardiolipin by Liquid Chromatography Electrospray Ionization Mass Spectrometry.

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Advances in Applied Microbiology offers intensive reviews of the latest techniques and discoveries in this rapidly moving field. The editors are recognized experts and the format is comprehensive and instructive. Covers topics of historical interest Includes a discussion on foodborne pathogens Entire sections devoted to various topics such as genomics, and microbial genetics

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Allen I. Laskin, Joan W. Bennett, Geoffrey M. Gadd

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Advances in Microbial Physiology is one of the most successful and prestigious series from Academic Press, an imprint of Elsevier. It publishes topical and important reviews, interpreting physiology to include all material that contributes to our understanding of how microorganisms and their component parts work. First published in 1967, the editors have always striven to interpret microbial physiology in the broadest context and have never restricted the contents to traditional views of whole cell physiology. Now edited by Professor Robert Poole, University of Sheffield, Advances in Microbial Physiology continues to be an influential and very well reviewed series.

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This compendium provides a concise and up-to-date assessment of critical recent issues related to erythroid biology.  Developmental, epigenetic, methodological, biochemical, and clinical aspects are integrated to provide a powerful overview of their interrelationships and importance to the generation of the red cell.  The excitement generated by these novel observations and the anticipation of future directions in studies of the red cell is a highlight of this volume. The first comprehensive volume covering the breadth of the topic The latest advancements that lead to novel directions in the study of red cells An informative discussion of red cells as they relate to the essential oxygen-carrying component of the body

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This superbly illustrated work provides short accounts of the lives and scientific contributions of all of the major pioneers of Tropical Medicine. Largely biographical, the stories discussed enlighten a new generation of scientists to the advances made by their predecessors. Written by Gordon Cook, contributor to the hugely popular Mansons Tropical Diseases, this report discusses the pioneers themselves and offers a global accounting of their experiences at the onset of the discipline.

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Epilepsy is a neurological disorder that affects millions of patients worldwide and arises from the concurrent action of multiple pathophysiological processes. The power of mathematical analysis and computational modeling is increasingly utilized in basic and clinical epilepsy research to better understand the relative importance of the multi-faceted, seizure-related changes taking place in the brain during an epileptic seizure. This groundbreaking book is designed to synthesize the current ideas and future directions of the emerging discipline of computational epilepsy research. Chapters address relevant basic questions (e.g., neuronal gain control) as well as long-standing, critically important clinical challenges (e.g., seizure prediction). Computational Neuroscience in Epilepsy should be of high interest to a wide range of readers, including undergraduate and graduate students, postdoctoral fellows and faculty working in the fields of basic or clinical neuroscience, epilepsy research, computational modeling and bioengineering. Covers a wide range of topics from molecular to seizure predictions and brain implants to control seizures Contributors are top experts at the forefront of computational epilepsy research Chapter contents are highly relevant to both basic and clinical epilepsy researchers

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Interpersonal Relations Across the Life Course

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This volume (number 12) is subtitled Interpersonal Relations across the Life Course. It is inspired by the increased awareness in recent years of the way in which structural and psychosocial dimensions of the life course shape interpersonal relations. Interest in this issue has included both the maintenance of long-term relationships that may span many phases of the life course and the development of relationships that are specific to particular phases. The volume is a combination of invited and author initiated papers--all anonymously peer reviewed--that seeks to present a cohesive source of information on the multiform nature and influences of interpersonal relations from a variety of perspectives, theoretical frames, and substantive areas. Contributions reflect:Macro-micro linkages and interpersonal relations, (i.e., age structures, social institutions, and race/ethnicity) Parenting across the life course Parent-adult child relations and transitionsTransitions in non-kin relationshipsSocial relationships and well-being

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International Review of Cytology presents current advances and comprehensive reviews in cell biology  both plant and animal. Authored by some of the foremost scientists in the field, each volume provides up-to-date information and directions for future research.

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Laboratory Manual of Biomathematics is a companion to the textbook An Invitation to Biomathematics. This laboratory manual expertly aids students who wish to gain a deeper understanding of solving biological issues with computer programs.

It provides hands-on exploration of model development, model validation, and model refinement, enabling students to truly experience advancements made in biology by mathematical models. Each of the projects offered can be used as individual module in traditional biology or mathematics courses such as calculus, ordinary differential equations, elementary probability, statistics, and genetics. Biological topics include: Ecology, Toxicology, Microbiology, Epidemiology, Genetics, Biostatistics, Physiology, Cell Biology, and Molecular Biology .

Mathematical topics include Discrete and continuous dynamical systems, difference equations, differential equations, probability distributions, statistics, data transformation, risk function, statistics, approximate entropy, periodic components, and pulse-detection algorithms. It includes more than 120 exercises derived from ongoing research studies.

This text is designed for courses in mathematical biology, undergraduate biology majors, as well as general mathematics. The reader is not expected to have any extensive background in either math or biology.
Can be used as a computer lab component of a course in biomathematics or as homework projects for independent student work Biological topics include: Ecology, Toxicology, Microbiology, Epidemiology, Genetics, Biostatistics, Physiology, Cell Biology, and Molecular Biology Mathematical topics include: Discrete and continuous dynamical systems, difference equations, differential equations, probability distributions, statistics, data transformation, risk function, statistics, approximate entropy, periodic components, and pulse-detection algorithms Includes more than 120 exercises derived from ongoing research studies