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"Its continuity of pertineence, excellence, and authority remains unbroken - a tribute to the skillful editing and writing involved. Every informed laboratory staff must have available a copy of this volume."
- CLINICAL CHEMISTRY

For more than thirty years, this serial has helped to broaden the technical scope and expand the scientific base of clinical chemistry. These volumes will clarify the areas of molecular biology, informatics, and the monitoring of physiological parameters in crticial situations as they pertain to clinical chemistry. Each volume of Advances in Clinical Chemistry contains an index, and each chapter includes references.

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Advances in the Study of Behavior remains one of the most-turned-to sources for penetrating insight on the latest findings in behavior research. This serial has kept pace with the vigorous multidisciplinary growth of the field and covers all major aspects, from ecology to endocrinology, in both human and animal subjects. Critical reviews, presentations of major research programs, and communication of significant new concepts provide readers with an up-to-date overview of the latest developments in this field.<br>The series does not focus narrowly on one or a few fields, but features articles covering the best behavioral work from a wide spectrum. The skill and concepts of scientists in such diverse fields necessarily differ, making the task of developing cooperation and communication among them a difficult one. But it is one that is of great importance, and one to which the editors and publisher of Advances in the Study of Behavior are committed. Each volume of Advances in the Study of Behavior contains an index, and each chapter includes references.

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Peter J.B. Slater, Colin Beer, Manfred Milinski, Jay S. Rosenblatt

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International Review of Research in Mental Retardation

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This volume addresses three important areas of current research in mental retardation: behavioral toxicology research and its implications for the cause and prevention of some types of mental retardation, cognitive processes in mentally retarded individuals and the significance of this issue for the further development of remediation techniques, and social adaptation and family functioning and the importance of these topics for the study of mental retardation.

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This volume contains reviews highlighting some of the most important achievements in understanding the molecular basis of cancer. Included are reviews on human papilloma virus and tumor suppressor gene products, the function of SH2 and SH3 domains in tyrosine kinase signal transduction, oncogene activation in mammary tumors, the phenotypes of polyoma middle T antigen in transgenic animals, and the role of protein kinase C and FCg receptors in neoplastic disease. Transgenic animal models for the study of molecular events in cancer are especially featured in these reviews.

* Highlights of Volume 64:* Interactions of papilloma virus proteins with tumor suppressors* Retinoblastoma tumor suppressor protein* SH2 and SH3 domains in tyrosing kinase signal transduction* Oncogene activation in mammary tumors* Polyomavirus middle T antigen phenotypes in transgenic animals* Protein kinase C and FCg receptors in neoplastic disease* Transgenic mouse models for molecular carcinogenesis

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Under new editorial direction, Advances in Agronomy both continues its long tradition and expands to include innovative methods and technologies. Leading international scientists cover topics in plant and soil sciences, biotechnology, terrestrial ecosystems, and environmental concerns.The second volume under new editorial direction, Advances in Agronomy, Volume 47 focuses on environmental quality and biotechnology. Four articles on soil science cover acid deposition, chemical transport, and surface complexation. Two articles on crop science survey variety fingerprinting and corn evolution. This and related volumes will be of interest to agronomists and biotechnologists in academe, industry, and government. Acidic deposition in forested soils Modeling organic and inorganic chemical transport in soils Surface complexation models in soil chemical systems Fingerprinting crop varieties Evolution of corn

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Molecular Biology of Receptors and Transporters: Bacterial and Glucose Transporters

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This multi-volume set within International Review of Cytology encompasses the recent advances in the understanding of structure-function relationships at the molecular level of receptors, transporters, and membrane proteins. Several diverse families of membrane receptors/proteins are discussed with respect to the molecular and cellular biology of their synthesis, assembly, turnover, and function. Included are such receptor superfamilies as G-proteins, immunoglobulins, ligand-gated receptors, interleukins, and tyrosine kinases as well as such transporter/protein families as pumps, ion channels, and bacterial transporters. Each section of each volume also features a "perspectives/commentary" chapter which includes comments on the recent advances and predictions on new directions. Volume 137A highlights the recent advances in bacterial and glucose transporter mechanisms.

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Kwang W. Jeon, M. Friedlander, Michael Mueckler

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Continuing the international tradition, Volume 49 of Advances in Agronomy highlights current areas of interest to both researchers and students of agronomy. Areas covered include phosphogypsum in agriculture, nutrient cycling and soil fertility in the grazed pasture ecosystem. It also discusses the current use of computer assisted tomography (CAT) in studying water movement around plant roots as well as future applications of CAT in agronomy, and electrical conductivity methods for measuring and mapping soil salinity.

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Continuing the international tradition of Advances in Agronomy, Volume 48 highlights crop and soil science including hybrid improvement in tropical maize, pearl millet as food, feed and forage, cotton host plant resistance to insects, and electrochemical techniques applied to soils. This volume should be of interest to researchers and students in agronomy.

Key Features* Maize, pearl millet, and cotton crops* Reactions and availability of nickel in soils* Electrochemical techniques for soil analysis

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The Biochemical Ecology of Marine Fishes

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This volume is dedicated to an in-depth discussion of the biochemical ecology of marine fishes. The authors review fish biology with regard to the environment and the world's fisheries. They show how fish can be assessed for harvesting at the best time in their life cycles and in the correct condition for marketing, freezing, and preserving. In this context, they include coverage of adaptations of fish to the environment, life cycles, and metabolism. This volume will be of interest to biochemists, marine ecologists, and fishery scientists.

Advances in Marine Biology has always offered marine biologists an in-depth and up-to-date review on a variety of topics. As well as many volumes that provide a selection of important topics, the series also includes thematic volumes that examine a particular field in detail.

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This volume deals for the most part, with current status of four groups of alkaloids of substantial biological releavance. Chapter 1 by Lounasmaa and Tolvanen, focuses on the "Eburanmine-Vincamine Alkaloids," and discusses the new alkaloids, and the extensive synthetic and pharmacologic work that has been conducted since the last review in 1981.  Clark and Hufford present a review which focuses on the "Antifungal Alkaloids," especially those compounds that might be important as lead structures for the development of agents usefulin treating the opportunistic infections associated with AIDS.  Wang and Liang bring up-to-date the area of the diterpenoid alkaloids from a chemical perspective.  Over the years this large group of alkaloids has produced a fascinating array of molecular gyrations.  Finally, Wrobel and Wojtasiewicz revisit the topic of "Sulfur-Containing Alkaloids" (which was last covered in Volume 26) from a chemical and biological perspective.

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Published since 1959, this serial presents in-depth reviews of key topics in neuroscience, from molecules to behavior. The serial stays keenly atuned to recent developments through the contributions of first-class experts in the many fields of neuroscience. Neuroscientists as well as clinicians, psychologists, physiologists and pharmacoloists will find this serial an indispensable addition to their library.

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Techniques for the Study of Mycorrhiza, Part II

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Volumes 23 and 24 of this highly acclaimed series focus on methods used for the study of both ectomycorrhiza and vesicular-arbuscular mycorrhiza. Written by a team of international experts, these volumes comprise the most extensive compilation of methods available on this topic.

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J. R. Norris, David J. Read, A. K. Varma

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Published since 1959, this serial presents in-depth reviews of key topics in neuroscience, from molecules to behavior. The serial stays keenly atuned to recent developments through the contributions of first-class experts in the many fields of neuroscience. Neuroscientists as well as clinicians, psychologists, physiologists and pharmacoloists will find this serial an indispensable addition to their library.

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Microcompartmentation and Phase Separation in Cytoplasm

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International Review of Cytology presents current advances and comprehensive reviews in cell biology-both plant and animal. Articles address structure and control of gene expression, nucleocytoplasmic interactions, control of cell development and differentiation, and cell transformation and growth. Authored by some of the foremost scientists in the field, each volume provides up-to-date information and directions for future research.This volume provides an overview of major cytoplasmic properties and events which including cytoarchitecture and the physical properties of cytoplasm, molecular compartmentation and gradients, channeling, sorting, and trafficking. It also addresses physicochemical events, both measured and anticipated, which attend solutions under conditions prevailing in cytoplasm: molecular crowding. It summarizes the current state of knowledge in the field and considers questions such as how molecules in cytoplasm interact.

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Kwang W. Jeon, Harry Walter, Donald E. Brooks, Paul A. Srere

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International Review of Cytology presents current advances and comprehensive reviews in cell biology-both plant and animal. Articles address structure and control of gene expression, nucleocytoplasmic interactions, control of cell development and differentiation, and cell transformation and growth. Authored by some of the foremost scientists in the field, each volume provides up-to-date information and directions for future research. Body Patterning in the Early Amphibian Embryo Calcium Regulation of the Actin-Myosin Interaction Characteristics of Skeletal Muscle Phosphate Transport and Homeostasis in Plant Cells Synaptic-like Microvesicles in Mammalian Pinealocytes Invertebrate Integrin

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Interest in the factors controlling the spread of pathogenic bacteria in both human and animal populations has led, in recent years, to the development of various techniques for the characterization of isolates from epidemics. These take many forms. Biochemical tests, serological analysis, phage and bacterocin typing are particularly important. Volumes 10-13 of Methods in Microbiology collect together, for the first time, the methods used in identifying all major human and animal pathogenic bacteria of epidemiological importance. The attention to practical detail will enable the methods to be followed in the laboratory, and it is hoped that this will lead to increased uniformity of methods around the world.<br>These volumes will be of value to workers in epidemiology, clinicians working in infectious disease clinics, microbiologists concerned with environmental health and general microbiologists wanting an insight into current thinking and practice concerning the identification of bacteria at the species and sub-species level.