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For more than thirty years, this serial has broadened the technical scope and expanded the scientific base of clinical chemistry. These volumes clarify the areas of molecular biology, informatics, and the monitoring of physiological parameters in critical situations as they pertain to clinical chemistry. Each volume of Advances in Clinical Chemistry contains an index, and each chapter includes references.

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The Zebrafish, Volume II Genetics and Genomics

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This is the second volume of a two-volume, comprehensive treatment of the methodologies used in researching the zebrafish, an emerging vertebrate model system. The text includes discussions on development, genetic methodologies, and model applications.

Key Features* Details state-of-the-art zebrafish protocols in a single-source reference* Presents methods and reagents in user-friendly format* Delineates critical steps and pitfalls of he procedures* Illustrates techniques with full-color plates* Summarizes many new and interesting developmental mutants* Includes appendices with strain information and a compendium of zebrafish World Wide Web sites* Relevant to clinicians interested in vertebrate models of human congenital diseases

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Leslie Wilson, Paul T. Matsudaira, H. William Detrich III, Monte Westerfield, Leonard I. Zon

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International Review of Research in Mental Retardation

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This serial was established under the editorship of Dr. Norman R. Ellis in 1966. As a result of his editorial effort and the contributions of many authors, the serial is now recognized as the area's best source of reviews of behavioral research on mental retardation. From its inception, active research scientists and graduate students in mental retardation have looked to this serial as a major source of critical reviews of research and theory in the area.

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International Review of Cytology presents current advances and comprehensive reviews in cell biology-both plant and animal. Articles address structure and control of gene expression, nucleocytoplasmic interactions, control of cell development and differentiation, and cell transformation and growth. Authored by some of the foremost scientists in the field, each volume provides up-to-date information and directions for future research. Role of Rab GTPases in Membrane Traffic Lignification in Plant Cell Walls Cytoskeleton, Membranes, and Cell Wall Interactions in the Pollen Tube of Flowering Plants Biology of the Postsynapic Glycine Receptor Cell Fate Specification in Ascidian Embryos Distribution of Na+, K+-ATPase in Insect Photoreceptor Cells

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Advances in Marine Biology contains up-to-date reviews of all areas of marine science, including fisheries science and macro/micro fauna. Each volume contains peer-reviewed papers detailing the ecology of marine regions. Up-to-date reviews on marine biology Particular focus on plankton, fisheries, and crustacea Volume 31 includes taxonomic index, cumulative index of titles, and cumulative index of authors for Volumes 1-31

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Written by international authorities in agronomy, Volume 62 contains five comprehensive reviews covering key contemporary topics on crop and soil sciences. As always, the topics are varied and exemplify the wide array of subject matter covered by this long-running serial. With this latest volume, Advances in Agronomy continues to be recognized as a leading reference and as a first-rate source of the latest research in agronomy, crop science, and soil science.

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Advances in Botanical Research is a multi-volume publication that brings together reviews by recognized experts on subjects of importance to those involved in botanical research. For more than thirty years, Advances in Botanical Research has earned a reputation for excellence in the field. For those working on plant pathology, Advances in Plant Pathology has also carved a niche in the plant sciences during its decade of publication.
Academic Press has merged Advances in Plant Pathology into Advances in Botanical Research. The plant science community will find that the merger of these two serials will provide one comprehensive resource for the field. To ensure complete coverage, John Andrews and Inez Tommerup, the editors of Advances in Plant Pathology, have joined the editorial board of the new series, which will include equal coverage of plant pathology and botany in both thematic and mixed volumes. The first fewvolumes of the new series will be slanted toward botany or plant pathology; however, future eclectic volumes will be fully integrated.
The resulting synergy of these two serials greatly benefits the plant science community by providing a more comprehensive resource under one roof. The joint aim is to continue to include the very best articles, thereby maintaining the status of a high impact factor review series.

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This volume contains papers highlighting the diverse interests of modern ecologists. Areas covered range from physiological and evolutionary ecology to ecosystem ecology. Papers address the longevity of roots, the importance of wind dispersal to the population ecology of nocturnal insects, the different functions of soil fauna, 15N abundance in an old field ecosystem and forest productivity. This volume will be essential for all ecologists.

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This volume is an authoritative and comprehensive treatment of the approaches and techniques used for Green Fluorescent Proteins (GFP). The primary focus of this work is on research using biological systems. The volume covers all aspects of GFP, from its expression in different organisms to specific microscopic and data analysis methods.

Key Features* Only volume on Green Fluorescent Protein research* Covers all aspects of GFP* Provides specific microscopic and data analysis methods* Discusses the design and construction of GFP fusion proteins* Covers GFP expression in animals, insects, plants, and microbes* Details procedures for time lapse imaging of living cells* Explains how to implement single molecule fluorescence detection with GFP* Discusses dual label GFP strategies for multicolor fluorescence* Presents fluorescence resonance energy transfer methods with GFPs* Details quantitative fluorescence imaging techniques* Extensively illustrated with color photographs

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Leslie Wilson, Paul T. Matsudaira, Kevin F. Sullivan, Steve A. Kay

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Written by international authorities in agronomy, Volume 61 contains five comprehensive reviews covering key contemporary topics on crop and soil sciences. As always, the topics are varied and exemplary of the array of subject matter covered by this long-running serial. In this volume, a definitive treatise on dynamic conservation of plant genetic resources is included, as is an environmentally timely update on coal surface mine reclamation practices; contemporary and thorough reviews of diffusion in the soil-plant system, dorminancy, germinability, and germination in crop and weed seeds, and control of soil-borne plant pests. With this latest volume, Advances in Agronomy continues to be recognized as a leading reference and as a first-rate source of the latest research in agronomy, crop science, and soil science. The control of soil-borne plant pests Ion-diffusion in the soil-plant system Dormancy, germinability, and germination in crop and weed seeds Dynamic conservation of plant genetic resources Coal surface mine reclamation

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The Psychology of Learning and Motivation publishes empirical and theoretical contributions in cognitive and experimental psychology, ranging from classical and instrumental conditioning to complex learning and problem solving. Each chapter provides a thoughtful integration of a body of work. Includes computational models of human learning Provides contributions from ten leading researchers in the field Contains interdisciplinary perspectives on perceptual learning Synthesizes research from psychology and computer science Focuses on the specific mechanisms that drive perceptual learning

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Phillippe G. Schyns, Robert L. Goldstone, Douglas L. Medin

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Catecholamines: Bridging Basic Science with Clinical Medicine

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This volume in Advances in Pharmacology focuses on all aspects of catecholamine research, from very basic to medical. It is broad based and covers many areas within physiology and medicine.

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J. Thomas August, Ferid Murad, M. W. Anders, Joseph T. Coyle, David S. Goldstein, Graeme Eisenhofer, Richard McCarty

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Articles in this volume analyze rapidly evolving approaches, many at the cusp of development, to research plant defense mechanisms, pathogen variability, and epidemiology. Jones and Jones focus on emerging patterns that key resistance genes encode or require leucine-rich repeat proteins. Holub and Beynon analyze associating host resistance specificity with a locus and whether a phenotype is due to single or multiple genes. Ashby combines biochemical, molecular, and classical plant pathology to analyze interactions and provide leads to novel control strategies. Heath and Skalamera question why fungal biotrophs form intracellular structures, the significance of ensuing cellular rearrangements and death of invaded resistant cells. Spencer-Phillips explores the roles of haustoria and intercellular hyphae in intercepting organic and inorganic nutrients from hosts.Chamberlain and Ingram compare pathogen asexual and sexual reproduction for generating genetic variation, physiological and fitness costs and trade-offs. Hardham and Hyde consider new knowledge of sporangiogenesis and zoospore production in oomycetes. Dewey et al. analyze recent advances in accurately enumerating pathogens in soil. Wistemeyer et al. consider opportunities for horizontal gene transfer amongst microbes and plants in soil. Irwin et al. discuss origins of genetic variationof Phytophthora pathogens of pasture legumes. Rodriguez and Redman show how prominent pathogens which also behave as endophytes or saprophytes may influence plant community structure and dynamics. Haubold and Rainey challenge us to consider geneticvariation in plant-colonizing bacterial populations. Milgroom and Fry demonstrate that the practical need to understand pathogen variation is the most significant application of population genetics to disease management.

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Membrane Permeability: 100 Years Since Ernest Overton

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Membrane permeability is fundamental to all cell biology and subcellular biology. The cell exists as a closed unit. Import and export depend upon a number of sophisticated mechanisms, such as active transport, endocytosis, exocytosis, and passive diffusion. These systems are critical for the normal housekeeping physiological functions. However, access to the cell is also taken advantage of by toxic microbes (such as cholera or ptomaine) and when designing drugs.

Ernest Overton, one of the pioneers in lipid membrane research, put forward the first comprehensive theory of lipid membrane structure. His most quoted paper on the osmotic properties of cells laid the foundation for the modern concepts of membrane function, most notably important in anesthesia.

This book is designed to celebrate the centennial anniversary (in the first chapter) of Overton's work. Subsequent chapters present readers with up-to-date concepts of membrane structure and function and the challenge they pose for new explorations.
Provides an historical perspective of Overton's contributions to the theory of narcosis Presents an overview of each permeability mechanism, including active transport, endocytosis, exocytosis, and passive diffusion

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Dale J. Benos, David W. Deamer, Arnost Kleinzeller, Douglas M. Fambrough

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Mitosis and Meiosis details the wide variety of methods currently used to study how cells divide as yeast and insect spermatocytes, higher plants, and sea urchin zygotes. With chapters covering micromanipulation of chromosomes and making, expressing, and imaging GFP-fusion proteins, this volume contains state-of-the-art "how to" secrets that allow researchers to obtain novel information on the biology of centrosomes and kinetochores and how these organelles interact to form the spindle.

Chapters Contain Information On:* How to generate, screen, and study mutants of mitosis in yeast, fungi, and flies* Techniques to best image fluorescent and nonfluorescent tagged dividing cells* The use and action of mitoclastic drugs* How to generate antibodies to mitotic components and inject them into cells* Methods that can also be used to obtain information on cellular processes in nondividing cells

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Leslie Wilson, Paul T. Matsudaira, Conly L. Rieder

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Advances in the Study of Behavior continues to serve scientists across a wide spectrum of disciplines. Focusing on new theories and research developments with respect to behavioral ecology, evolutionary biology, and comparative psychology, these volumes foster cooperation and communication in these diverse fields.

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Peter J.B. Slater, Charles T. Snowdon, Jay S. Rosenblatt, Manfred Milinski

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International Review of Research in Mental Retardation

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This serial was established under the editorship of Dr. Norman R. Ellis in 1966. As a result of his editorial effort and the contributions of many authors, the serial is now recognized as the area's best source of reviews of behavioral research on mental retardation. From its inception, active research scientists and graduate students in mental retardation have looked to this serial as a major source of critical reviews of research and theory in the area.

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This volume provides complete and thorough coverage of the classical and state-of-the-art methods used in cell culture. It also includes basic principles used in the selection of cells for specific scientific study, as well as analytical and procedural techniques.

Key Features
* Reviews basic principles of cell culture
* Gives options and techniques on how to look at cells

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Leslie Wilson, Paul T. Matsudaira, Jennie P. Mather, David Barnes

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Written by international authorities in agronomy, Volume 60 contains five comprehensive reviews covering key contemporary topics on plant and soil sciences. As always, the topics are varied and exemplary of the array of subject matter covered by this long-running serial. This volume contains a state-of-the-art review on adapting plants to salinity, the effects of no-tillage cropping systems on soil microbiological relationships, sustainability of agroecosystems in semiarid regions, ethics in agronomic research, and nutrient cycling information. With this latest volume, Advances in Agronomy continues to be recognized as a leading reference and as a first-rate source of the latest research in agronomy, crop science, and soil science.

Key Features
* Nutrient cycling, transformation and flows
* Adaptation of plants to salinity
* Practical ethics in agronomic research
* The influence of no-till cropping systems on microbial relationships
* The sustainability of agroecosystems in semiarid regions

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Volume 59 contains seven reviews covering key contemporary topics on crop and soil sciences. As always, the topics are varied and exemplary of the array of subject matter covered by this long-running serial. Crop science is represented by chapters on quantitative genetics and plant breeding, wheat, perennial forages, and cotton. These chapters are balanced by synthetic reviews of organoclays in pollution abatement, the applications of micromorphology, and the importance of long-term field research. With this latest volume, Advances in Agronomy continues to be recognized as a leading reference and as a first-rate source of the latest research in agronomy, crop science, and soil science. Quantitative genetics Organoclays and pollution Phenology, development, and growth Micromorphology and agronomy Physiological and morphological responses to stress Crop modeling The value of long-term experiments