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Comprised of 12 chapters, this book begins with an overview of the physiology of bone, with emphasis on the structures produced by bone cells and the different hormones that influence them. The symptoms, signs, and investigation of metabolic bone disease are then described and compared. The following chapters focus on the biochemistry and clinical aspects of disorders affecting the skeleton, from osteoporosis and osteomalacia to Ehlers-Danlos syndrome, fibrous dysplasia, osteopetroses and hyperostoses, and fibrogenesis imperfecta ossium. The final chapter offers a short description of advances that have been made in understanding these biochemical disorders, including the significance of low-plasma calcitonin in women; the role of mithramycin in Paget's disease; and the identification of the different types of osteogenesis imperfecta. This monograph will be a valuable resource for physicians, pediatricians, and orthopedic surgeons.", "author": "Roger K. W. 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This book discusses the clinical and research implications of studies that use these techniques. This text is comprised of 14 chapters; the first of which introduces the reader to the origins and general principles of cytochemical bioassays, along with their advantages. This discussion is followed by a chapter that explains what is meant by \"\"an assay\"\"; for what purpose assays are done; the basic components of an assay method; and the nature of the difference between in vivo and in vitro hormone bioassays, in vitro ligand assays, and enzyme assays. Attention then turns to the techniques of cytochemical bioassays and the cytochemical bioassay procedures for adrenocorticotropic hormones; thyroid-stimulating hormones; the thyroid-stimulating antibody of Graves' disease; thyroid growth stimulating and blocking immunoglobulins; and luteinizing hormones. The next chapters focus on the technique and clinical relevance of a cytochemical bioassay for gastrin-like activity and for measurement of antidiuretic hormones, parathyroid hormones, angiotensin II, natriuretic hormones, and hypothalamic regulating hormones. 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All the patients presented to the Department of Neurology including those with more obscure diagnoses. The book consists of 12 exercises, each of six cases broadly corresponding to the style of the MRCP (UK) written case history papers. Each case is set out with the history and physical findings given first. There follows either a series of questions or true/false statements on one side of the page which the reader should attempt before continuing on to the answer section on the other side. There then follows a short discussion about each case and a single reference. This book is intended for those doctors studying for higher professional qualifications such as the MRCP, although it may be of interest and use to medical students approaching their final examinations.", "author": "G. S. Venables, D. Bates, N. E. F. 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This book covers the most important areas of maternofetal medicine and presents different views of the critical problems of development. The various components of fetal metabolism are highlighted to demonstrate how animal experimentation has given a clear view of the interrelationship of the mother, placenta, and fetus. This text is comprised of 24 chapters; the first of which describes the use of ultrasound in antenatal diagnosis of congenital structural anomalies. This topic is followed by a discussion on sexual differentiation, acquired immunity, and endocrine changes, as well as the physiology of breathing, the control of the fetal cardiovascular system, lung maturation, fetal infections, and the effects of hypoxia on the fetal brain. This book also provides comprehensive reviews of fetal regulatory mechanisms, such as the reninangiotensin system, water metabolism, and fetal and placental hormone production. Other chapters focus on clinical applications, such as antenatal fetal heart rate monitoring, the technical aspects of fetal and uterine pressure measurements, fetal acid-base balance, and the prevention of preterm delivery. A section that explores the transition from intrauterine to extrauterine life concludes this book. This source is of great potential value to all students and practitioners of reproductive medicine.", "author": "Richard W. Beard, Peter W. 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Topics covered include the equipment and technique for constant-current coulometry and controlled-potential coulometry; titrations in organic and inorganic analysis using constant-current coulometry; and applications of controlled-potential coulometry to analysis of organic and inorganic compounds. This book is comprised of seven chapters and begins by introducing the reader to the principles of electrolysis and the emergence of coulometry as a technique in analytical chemistry. The distinction between coulometry at constant current and coulometry at constant potential is considered, along with the difficulties associated with each technique. The next chapter examines the electrochemistry of each system. The discussion then turns to the equipment and technique for constant-current coulometry, coulometers for controlled-potential coulometry, and controlled-potential coulometric titrators. The use of controlled-potential coulometry in the analysis of organic and inorganic compounds is also discussed. The final chapter presents some papers of major importance in the historical development of coulometry as an analytical method. This book will be of interest to undergraduate students and practicing analytical chemists, as well as those who wish to learn the great development in analytical chemistry in general, or electro analytical chemistry in particular.", "author": "G. W. C. Milner, G. M. Phillips, R. J. 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It should help relieve some of the information storage burden of the specialist and should aid the nonspecialist who is seeking help with a specific problem to become rapidly aware of recent synthetic advances. In producing this volume the editors abstracted 48 primary chemistry journals, selecting useful synthetic advances. All reactions and methods which are new, synthetically useful, and reasonably general are included. Each entry is comprised primarily of structures accompanied by very few comments. The purpose of this is to aid the reader in rapidly scanning the book. Chapters I-III are organized by reaction type and constitute the major part of the book. Chapter IV deals with methods of synthesizing heterocyclic systems. Chapter V covers the use of new protecting groups. Chapter VI is divided into three main parts and covers those synthetically useful transformations that do not fit easily into the first three chapters. The first part deals only with functional group synthesis. The second part covers ring expansion and contraction, and the third part involves useful multistep sequences.", "author": "L. G. Wade, Martin J. 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Topics covered range from carbon-carbon bond forming reactions to oxidations, reductions, synthesis of heterocycles, and synthetic preparations. This book consists of seven chapters and begins with a list of papers on carbon-carbon bond forming reactions, including carbon-carbon single, double, and triple bonds as well as cyclopropanations and synthesis through organometallics. The following chapters focus on oxidations and reductions; methods of synthesizing heterocyclic systems such as lactams and lactones; and the use of protecting groups. Synthetically useful transformations are considered next, with emphasis on functional group synthesis, additions to alkenes or alkynes, and sulfur compounds. The final chapter deals with other reviews of topics ranging from asymmetric synthesis and molecular recognition to reactive intermediates; organometallics and organometalloids; halogen compounds and halogenation; and natural products. This monograph will appeal to organic chemists, both specialist and nonspecialist in synthesis.", "author": "Kenneth Turnbull, Phillip Weintraubull, Daniel M. 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This volume covers a wide range of preparative approaches, physics phenomena, and applications related to thin films. This book is comprised of four chapters and begins with a discussion on metal coatings and protective layers for front surface mirrors used at various angles of incidence from the ultraviolet to the far infrared. Thin-film materials and deposition conditions suitable for minimizing reflectance changes with angle of incidence are described, along with novel oxide protective coatings with enhanced chemical stability and mechanical durability. The next chapter offers a comprehensive treatment of photoemissive materials. After giving a rather detailed review of the physics of photoemission, the main classes of thin-film photoemitters, including Ag-O-Cs, alkali antimonides, and negative-electron affinity photocathodes, are considered. A description of field-assisted cathodes potentially suitable for wavelengths beyond 1.1 micrometers, such as transferred-electron structures and field-emission arrays, is also given. The reader is then introduced to spray pyrolysis and the solution growth technique for chemical solution deposition of inorganic films. This text concludes with a chapter on plasma-enhanced chemical vapor deposition of thin films, paying particular attention to the experimental conditions required for a range of element and compound materials as well as some of the unusual film properties and structures achieved by this approach. This monograph will be useful to students and practitioners of physics, especially those interested in thin films.", "author": "Georg Hass, Maurice H. Francombe, John L. 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This text also explores the disordered muscle tone, a term used to describe the sensation of resistance felt by the clinician as he manipulates a joint through a range of movement with the subject attempting to relax. Other chapters discuss the basal ganglia and their disorders and the cerebellum and its disorders. The anatomy and physiology of the special senses, cranial nerves, and autonomic nervous system are also explained. The last three chapters elucidate consciousness, unconsciousness, epilepsy, and the relationship between brain and mind. This book will be useful to those in the field of clinical neurology.", "author": "James W. Lance, James G. 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The most common in-lake techniques or procedures, plus nutrient diversion, are reviewed with regard to their scientific basis, methods of application, known effectiveness, feasibility, drawbacks, and costs. Areas for further research and development are also highlighted. This book is comprised of 16 chapters organized into four sections. After an introduction to the theory of the problem and the restoration technique, the discussion turns to the various restoration methods such as those used for physical and chemical control of nutrients. Diversion and advanced waste treatment, hypolimnetic withdrawal, and dilution and flushing are considered along with phosphorus precipitation and inactivation, sediment oxidation, sediment removal, and hypolimnetic aeration. Case studies and success stories are presented and the costs and potential negative impacts of the methods are examined. The following chapters focus on methods to control plant biomass, including artificial circulation, water-level drawdown, harvesting, biological control, and surface and sediment covers. A chapter on liming acidified lakes concludes this text. This monograph will be useful to professional limnologists and engineers, on-site lake or reservoir managers, and those who are interested in learning about the problems and management of lakes and reservoirs.", "author": "G. Dennis Cooke, Eugene B. Welch, Spencer A. 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Topics covered range from carbon-carbon bond forming reactions to oxidations, reductions, synthesis of heterocycles, and synthetic preparations. This book consists of seven chapters and begins with a list of papers on carbon-carbon bond forming reactions, including carbon-carbon single, double, and triple bonds. The chapters that follow focus on oxidations and reductions, methods of synthesizing heterocyclic systems, and the use of protecting groups. Synthetically useful transformations that do not fit easily into the first three chapters are considered next, with emphasis on functional group synthesis, ring expansion and contraction, and useful multistep transformations. The final chapter deals with miscellaneous reviews on topics ranging from cycloadditions to asymmetric catalysis, metalation, electrophilic substitutions, and pyrylium-mediated transformations of primary amino groups into other functional groups. 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