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Either in the form of reviews or of original presentations, the various authors proffer observations and ideas that generally relate to the regulation of the immune response at the molecular and cellular levels. The topic of Molecules encompasses the effect of molecular aggregation upon the triggering of physiological events, cooperative binding, and the expression of immunoglobulins during the lymphocyte differentiation process. Under the heading of Cells, there are contributions dealing with the physiological and pathological roles of interiorized antibodies; the mechanisms of antigen recognition by T cells; and the synthesis of membrane proteins by myeloma cells which somehow protect them from killer T cells. The section on Parasites includes some unique contributions on the immunology of human and animal cysticercosis and amebiasis, complemented by a general discussion of host-parasite relationships.", "author": "Carlos Larralde, Kaethe Willms, Librado Ortiz-Ortiz", "slug": "molecules-cells-and-parasites-in-immunology-294935-9781483270265", "thumbnail_image": "//redshelf-images.s3-external-1.amazonaws.com/thumbnail/9781483270265.jpg", "default_thumbnail_image": "//redshelf-images.s3-external-1.amazonaws.com/thumbnail/default_book_thumbnail.jpg", "product_type": "book", "product_id": "294935", "product_url": "/app/ecom/book/294935/molecules-cells-and-parasites-in-immunology-294935-9781483270265", "bisac_codes": [ "NAT019000", "SCI070030" ], "items_count": null, "identifiers": { "ISBN13": "9780124368408", "EISBN13": "9781483270265", "EISBN10": "1483270262" }, "drm": null, "cover_image": null, "default_cover_image": null, "book_type": null }, "relationships": { "lowest_offering": { "data": { "type": "offerings", "id": "00010026356338" } } } }, { "type": "Product", "id": "00010000294934", "attributes": { "name": "Underwater Physiology", "subtitle": "Proceedings of the Fourth Symposium on Underwater Physiology", "description": "Underwater Physiology is a collection of papers that deals with the physiologically limiting effects of undersea, high pressure exposure ranging from fundamental biological reactions, through integration of physiological stresses, and to limits actually experienced in deep diving. Papers discuss oxygen, the mechanisms of toxicity, and the effects of oxygen on cells and systems such as its pathological and physiological influences in the neurosensory ocular tissue. Other papers discuss the physical effects of pressure and gases on cellular function, protein structure, and the possibility of alleviating symptoms through the administration of drugs. Tests in mice show that various gases exhibit qualitative and semi-quantitative differences in the characteristics of sickness, reactions to hypoxia, and the time before the onset of symptoms. A computer, programmed for nonlinear gas transfer and other variables, running in real time can compute directly from the breathing mixture and provide a real time solution to decompression sickness under various conditions. A combined therapeutic approach, recompression and dextran (an effective lipemic clearing agent) should be capable of treating decompression sickness in humans. Other papers investigate the influence of inert gases and pressure on the central nervous system, as well as, situations in undersea and manned chamber operations. This collection can prove valuable for physiologists, biochemists, cellular biologists, and researchers involved in deep sea diving.", "author": "C. J. Lambertsen", "slug": "underwater-physiology-294934-9781483272559", "thumbnail_image": "//redshelf-images.s3-external-1.amazonaws.com/cover_image/9781483272559.jpg", "default_thumbnail_image": "//redshelf-images.s3-external-1.amazonaws.com/thumbnail/default_book_thumbnail.jpg", "product_type": "book", "product_id": "294934", "product_url": "/app/ecom/book/294934/underwater-physiology-294934-9781483272559", "bisac_codes": [ "MED075000", "SCI036000" ], "items_count": null, "identifiers": { "ISBN13": "9780124347502", "EISBN13": "9781483272559", "EISBN10": "1483272559" }, "drm": null, "cover_image": null, "default_cover_image": null, "book_type": null }, "relationships": { "lowest_offering": { "data": { "type": "offerings", "id": "00010026354240" } } } }, { "type": "Product", "id": "00010000294933", "attributes": { "name": "Equations of Membrane Biophysics", "subtitle": "", "description": "Equations of Membrane Biophysics provides an introduction to the relevant principles of thermodynamics, kinetics, electricity, surface chemistry, electrochemistry, and other mathematical theorems so that the quantitative aspects of membrane phenomena in model and biological systems could be described. The book begins by introducing several phenomena that arise across membranes, both artificial and biological, when different driving forces act across them. This is followed by separate chapters on thermodynamic principles related to properties of dilute aqueous electrolyte solutions along with a review of the principles of electrostatics, electrochemical principles, Fick's laws of diffusion, and the rate theory of diffusion; the quantitative aspects of the electrochemistry of solutions and membranes, and the quantitative relations between charges and electrostatic potentials related to surfaces and interfaces; and membrane theories pertaining to electrical potentials arising across a variety of membranes. Subsequent chapters deal with steady-state thermodynamic approaches to several transport phenomena in membranes; tissue impedance, cable theory, and Hodgkin-Huxley equations; and fluctuation analysis of the electrical properties of the membrane.", "author": "N Lakshminarayanaiah", "slug": "equations-of-membrane-biophysics-294933-9781483272160-n-lakshminarayanaiah", "thumbnail_image": "//redshelf-images.s3-external-1.amazonaws.com/thumbnail/9781483272160.jpg", "default_thumbnail_image": "//redshelf-images.s3-external-1.amazonaws.com/thumbnail/default_book_thumbnail.jpg", "product_type": "book", "product_id": "294933", "product_url": "/app/ecom/book/294933/equations-of-membrane-biophysics-294933-9781483272160-n-lakshminarayanaiah", "bisac_codes": [ "SCI008000", "907" ], "items_count": null, "identifiers": { "ISBN13": "9780124342606", "EISBN13": "9781483272160", "EISBN10": "1483272168" }, "drm": null, "cover_image": null, "default_cover_image": null, "book_type": null }, "relationships": { "lowest_offering": { "data": { "type": "offerings", "id": "00010026351667" } } } }, { "type": "Product", "id": "00010000294932", "attributes": { "name": "The Mammary Gland / Human Lactation / Milk Synthesis", "subtitle": "", "description": "Lactation: A Comprehensive Treatise, Volume IV, The Mammary Gland/Human Lactation/Milk Synthesis, forms the fourth in a series. When the first three volumes were published in 1974, publication of future volumes was not contemplated. However, the gratifying acceptance by the scientific community and the continuation of rapid advances in lactation, have provided the impetus for the continuation of the series. The present volume is concerned with general aspects of the mammary gland, human lactation, and mechanisms of milk synthesis. The volume is divided into three main parts. Part I covers some aspects of the mammary gland and lactation not discussed in the first three volumes and expands on others. Topics discussed include the development of the mammary apparatus and neuroendocrine control of lactation. Part II is devoted to more specific consideration of human lactation as a whole. It includes studies on breast feeding and the breast cancer process. Part III on milk synthesis deals with the mechanisms of milk synthesis; enzymology and control of lactose biosynthesis; molecular aspects of milk protein biosynthesis; and ion and water transport in the mammary gland.", "author": "Bruce L. 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The book provides the fundamental definitions of sound, its measurement, and concepts of the basic functioning, and the attributes of the auditory system. The text also presents along with their experimental basis, procedures for estimating from physical measures of noise its effects on man's auditory system and speech communications. The last part of the book is devoted to man's nonauditory system responses and includes information about the effects of noise on work performance, sleep, feelings of pain, vision, and blood circulation.", "author": "Karl D. Kryter, Douglas H.K. Lee, E. Wendell Hewson, C. Fred Gurnham", "slug": "the-effects-of-noise-on-man-294931-9781483272627-karl-d-kryter", "thumbnail_image": "//redshelf-images.s3-external-1.amazonaws.com/cover_image/9781483272627.jpg", "default_thumbnail_image": "//redshelf-images.s3-external-1.amazonaws.com/thumbnail/default_book_thumbnail.jpg", "product_type": "book", "product_id": "294931", "product_url": "/app/ecom/book/294931/the-effects-of-noise-on-man-294931-9781483272627-karl-d-kryter", "bisac_codes": [ "PSY024000", "711" ], "items_count": null, "identifiers": { "ISBN13": "9780124274501", "EISBN13": "9781483272627", "EISBN10": "1483272621" }, "drm": null, "cover_image": null, "default_cover_image": null, "book_type": null }, "relationships": { "lowest_offering": { "data": { "type": "offerings", "id": "00010026344467" } } } }, { "type": "Product", "id": "00010000294930", "attributes": { "name": "An Analysis of the Determinants of Occupational Upgrading", "subtitle": "", "description": "An Analysis of the Determinants of Occupational Upgrading presents a study that focuses on occupational mobility as a proxy measure for job upgrading. This monograph was first prepared in 1975 as a final report to the Manpower Administration of the U.S. Department of Labor. It is the second monograph of the Institute for Research on Poverty to deal with black-white income differentials and is also part of a growing Institute literature on the dual labor market theories and occupational mobility. The book contains seven chapters and begins with an overview of occupational mobility in the United States. The next chapter considers previous attempts to test the dual labor market hypothesis and presents a model of occupational mobility to be used in testing five hypotheses on the determinants of occupational upgrading. Subsequent chapters discuss the Census and NLS samples and outline the empirical variables used to measure the variables specified in the model; the impact on occupational upgrading of formal vocational training, industry structure, and job tenure; and the impact of interfirm and interindustry mobility on occupational progression. The final chapter summarizes the empirical findings with respect to each of the five testable hypotheses and considers some policy conclusions drawn from the analysis.", "author": "Duane E. Leigh", "slug": "an-analysis-of-the-determinants-of-occupational-upgrading-294930-9781483267371-duane-e-leigh", "thumbnail_image": "//redshelf-images.s3-external-1.amazonaws.com/cover_image/9781483267371.jpg", "default_thumbnail_image": "//redshelf-images.s3-external-1.amazonaws.com/thumbnail/default_book_thumbnail.jpg", "product_type": "book", "product_id": "294930", "product_url": "/app/ecom/book/294930/an-analysis-of-the-determinants-of-occupational-upgrading-294930-9781483267371-duane-e-leigh", "bisac_codes": [ "BUS038000", "POL013000" ], "items_count": null, "identifiers": { "ISBN13": "9780124428508", "EISBN13": "9781483267371", "EISBN10": "1483267377" }, "drm": null, "cover_image": null, "default_cover_image": null, "book_type": null }, "relationships": { "lowest_offering": { "data": { "type": "offerings", "id": "00010026351128" } } } }, { "type": "Product", "id": "00010000294929", "attributes": { "name": "A New Approach to Scientific Computation", "subtitle": "", "description": "A New Approach to Scientific Computation is a collection of papers delivered at a symposium held at the IBM Thomas J. Watson Research Center on August 3, 1982. The symposium provided a forum for reviewing various aspects of an approach to scientific computation based on a systematic theory of computer arithmetic. Computer demonstration packages for standard problems of numerical mathematics are considered. Comprised of 12 chapters, this volume begins by summarizing an extensive research activity in scientific computation as well as the experience gained through various implementations of a new approach to arithmetic on diverse processors, including even microprocessors. A complete listing of the spaces that occur in numerical computations is presented, followed by a discussion of aspects of traditional computer arithmetic and a new definition of computer arithmetic. The properties of semimorphisms are also considered. Subsequent chapters focus on potential applications of programming packages to standard problems in numerical analysis implemented on a Z80 based minicomputer, with a PASCAL extension called PASCAL-SC as the programming language; methods for solving algebraic problems with high accuracy; and the use of a computer with floating-point arithmetic to obtain guaranteed sharp bounds for the value of an arithmetic expression. An extension of FORTRAN which satisfies contemporary requirements of numerical computation is also described. This book will be helpful to students and practitioners in the fields of computer science and applied mathematics.", "author": "Ulrich W. Kulisch, Willard L. Miranker", "slug": "a-new-approach-to-scientific-computation-294929-9781483272047", "thumbnail_image": "//redshelf-images.s3-external-1.amazonaws.com/thumbnail/9781483272047.jpg", "default_thumbnail_image": "//redshelf-images.s3-external-1.amazonaws.com/thumbnail/default_book_thumbnail.jpg", "product_type": "book", "product_id": "294929", "product_url": "/app/ecom/book/294929/a-new-approach-to-scientific-computation-294929-9781483272047", "bisac_codes": [ "MAT003000", "MAT029000" ], "items_count": null, "identifiers": { "ISBN13": "9780124286603", "EISBN13": "9781483272047", "EISBN10": "1483272044" }, "drm": null, "cover_image": null, "default_cover_image": null, "book_type": null }, "relationships": { "lowest_offering": { "data": { "type": "offerings", "id": "00010026353215" } } } }, { "type": "Product", "id": "00010000294928", "attributes": { "name": "Immunological Methods", "subtitle": "Volume IV", "description": "Immunological Methods, Volume IV provides information pertinent to the methods in immunological research. This book focuses on cells, clones, and cell lines, as well as on their components and secreted products. Organized into 21 chapters, this volume begins with an overview of hybridoma methodology as the most celebrated immunological method. This text then discusses cell fusion, hybridoma technology, and everything related to monoclonal antibodies. Other chapters consider another molecular biology method, which describes the procedure required for establishing a partitioned cDNA-library. This book provides as well a comprehensive analysis of mRNA populations in which every messenger species appears as a distinct element, and so provides accurate answers to questions concerning genetic complexity. The final chapter provides an example of how transgenic mice can be used to study the development of T cell repertoires. This book is a valuable resource for cell biologists, scientists, immunologists, and research workers.", "author": "Ivan Lefkovits, Benvenuto Pernis", "slug": "immunological-methods-294928-9781483265360", "thumbnail_image": "//redshelf-images.s3-external-1.amazonaws.com/thumbnail/9781483265360.jpg", "default_thumbnail_image": "//redshelf-images.s3-external-1.amazonaws.com/thumbnail/default_book_thumbnail.jpg", "product_type": "book", "product_id": "294928", "product_url": "/app/ecom/book/294928/immunological-methods-294928-9781483265360", "bisac_codes": [ "MED044000", "941" ], "items_count": null, "identifiers": { "ISBN13": "9780124427044", "EISBN13": "9781483265360", "EISBN10": "1483265366" }, "drm": null, "cover_image": null, "default_cover_image": null, "book_type": null }, "relationships": { "lowest_offering": { "data": { "type": "offerings", "id": "00010026355451" } } } }, { "type": "Product", "id": "00010000294927", "attributes": { "name": "Immunological Methods", "subtitle": "Volume III", "description": "Immunological Methods, Volume III provides information pertinent to the fundamental aspects of immunological methods. This book presents recombinant DNA technology as applied to immunology. Organized into 25 chapters, this volume begins with an overview of the major histocompatibility complex. This text then examines the use of monoclonal antibodies in the identification of lymphocyte membrane antigens and explains the use of monoclonal antibodies in histocompatibility typing. Other chapters consider the methods in two-dimensional electrophoretic analysis of proteins and another to lymphokines that support B cells. This book discusses as well the production and expansion of cloned B and T cell lines and hybridomas. The final chapter deals with the sophisticated methodology used with particular animal species, namely, birds, sheep, and amphibians to probe specific immunological questions. This book is a valuable resource for immunologists and investigators with extensive experience in using immunological methods. Protein chemists and biologists will also find this book useful.", "author": "Ivan Lefkovits, Benvenuto Pernis", "slug": "immunological-methods-294927-9781483269634", "thumbnail_image": "//redshelf-images.s3-external-1.amazonaws.com/thumbnail/9781483269634.jpg", "default_thumbnail_image": "//redshelf-images.s3-external-1.amazonaws.com/thumbnail/default_book_thumbnail.jpg", "product_type": "book", "product_id": "294927", "product_url": "/app/ecom/book/294927/immunological-methods-294927-9781483269634", "bisac_codes": [ "NAT019000", "SCI070030" ], "items_count": null, "identifiers": { "ISBN13": "9780124427037", "EISBN13": "9781483269634", "EISBN10": "1483269639" }, "drm": null, "cover_image": null, "default_cover_image": null, "book_type": null }, "relationships": { "lowest_offering": { "data": { "type": "offerings", "id": "00010026354764" } } } }, { "type": "Product", "id": "00010000294926", "attributes": { "name": "Population Patterns in the Past", "subtitle": "", "description": "Population Patterns in the Past focuses on the study of historical populations. This book presents methods for the exploitation and use of aggregate data for demographic inference, facilitating the development and testing of hypotheses with socioeconomic content through advances in the use of demographic time-series. The topics discussed include homeostatic demographic regime; peasant household organization and demographic change in lower Saxony; civil code and nuptiality; and primonuptiality and ultimonuptiality. The deaths, marriages, births, and the Tuscan economy; influence of economic and social variables on marriage and fertility in 18th and 19th century Japanese villages; and childbearing and land availability are also elaborated. This text also covers the American fertility patterns since the civil war; a repertory of stable populations; and methods and models for analyzing historical series of births, deaths, and marriages. This publication is recommended for demographists, historians, and sociologists in charge of analyzing behavioral models in historical demography.", "author": "Ronald Demos Lee", "slug": "population-patterns-in-the-past-294926-9781483270197", "thumbnail_image": "//redshelf-images.s3-external-1.amazonaws.com/cover_image/9781483270197.jpg", "default_thumbnail_image": "//redshelf-images.s3-external-1.amazonaws.com/thumbnail/default_book_thumbnail.jpg", "product_type": "book", "product_id": "294926", "product_url": "/app/ecom/book/294926/population-patterns-in-the-past-294926-9781483270197", "bisac_codes": [ "SOC002000", "SOC053000" ], "items_count": null, "identifiers": { "ISBN13": "9780124418509", "EISBN13": "9781483270197", "EISBN10": "148327019X" }, "drm": null, "cover_image": null, "default_cover_image": null, "book_type": null }, "relationships": { "lowest_offering": { "data": { "type": "offerings", "id": "00010026366295" } } } }, { "type": "Product", "id": "00010000294922", "attributes": { "name": "Topology", "subtitle": "Volume II", "description": "Topology, Volume II deals with topology and covers topics ranging from compact spaces and connected spaces to locally connected spaces, retracts, and neighborhood retracts. Group theory and some cutting problems are also discussed, along with the topology of the plane. Comprised of seven chapters, this volume begins with a discussion on the compactness of a topological space, paying particular attention to Borel, Lebesgue, Riesz, Cantor, and Bolzano-Weierstrass conditions. Semi-continuity and topics in dimension theory are also considered. The reader is then introduced to the connectedness of a space, with emphasis on the general properties and monotone mappings of connected spaces; local connectedness of a topological space; absolute retracts and contractible spaces; and general properties of commutative groups. Qualitative problems related to polygonal arcs are also examined, together with cohomotopic multiplication and duality theorems. The final chapter is devoted to the topology of a plane and evaluates the concept of the Janiszewski space. This monograph will be helpful to students and practitioners of algebra and mathematics.", "author": "K. 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This book gives a detailed account of the current state of the theory of nonlinear differential equations in a Banach space, and discusses existence theory for differential equations with continuous and discontinuous right-hand sides. Of special importance is the first systematic presentation of the very important and complex theory of multivalued discontinuous differential equations.", "author": "V. 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This book begins with a discussion on single-cell responses, followed by a discussion of sensory information processing that leads into models of perceptual processes and their possible neural bases. This text concludes with some general principles and theoretical investigations relating to units that make up a nervous system, through a sensory pathway and central structures. The peripheral stimuli that explain the operations of the brain are also described. This publication is a good reference for neurologists, medical practitioners, and researchers conducting work on the nervous system theory.", "author": "K. N. 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The papers explore trends in nonlinear phenomena in mathematical sciences, with emphasis on nonlinear functional analytic methods and their applications; nonlinear wave theory; and applications to medical and life sciences. In the area of nonlinear functional analytic methods and their applications, the following subjects are discussed: optimal control theory; periodic oscillations of nonlinear mechanical systems; Leray-Schauder degree theory; differential inequalities applied to parabolic and elliptic partial differential equations; bifurcation theory, stability theory in analytical mechanics; singular and ordinary boundary value problems, etc. The following topics in nonlinear wave theory are considered: nonlinear wave propagation in a randomly homogeneous media; periodic solutions of a semilinear wave equation; asymptotic behavior of solutions of strongly damped nonlinear wave equations; shock waves and dissipation theoretical methods for a nonlinear Schr?dinger equation; and nonlinear hyperbolic Volterra equations occurring in viscoelasticity. Applications to medical and life sciences include mathematical modeling in physiology, pharmacokinetics, and neuro-mathematics, along with epidemic modeling and parameter estimation techniques. This book will be helpful to students, practitioners, and researchers in the field of mathematics.", "author": "V. 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The book opens with an integrative view of the role of lymphokines in the generation of fever. It stresses that pirogenicity is the attribute of more than one lymphokine: interleukin 1 (IL-1), interferon a, and tumor necrosis factor (TNF) all possess this quality. This is followed by separate chapters on the chemistry of IL-1 molecules and cloning of the gene for human monocyte IL-1; the production of lymphokine by cells of the central nervous system; the acute phase plasma protein response studied at the level of gene structure and expression; and the involvement of calcium and calcium-linked enzymes in T cell proliferation. Subsequent chapters deal with the involvement of pteridines in T cell activation; the discovery of cachectin and the establishment of its identity with TNF; the effect of IFN-? and several cytotoxic cytokines on the proliferation, differentiation, and function of normal and leukemic myeloid cells; and the cytotoxic lymphokines produced by effector T cells. 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