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GET /services/catalog/products?format=api&page=74358
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The next chapter deals with the molecular genetics and polymorphism of of class II (Ia) antigens, as well as the correlation between immunogenetic and molecular genetic maps. The antigen-specific T cell clones and the specific factors derived from them are then examined. The last chapter considers the relationship between infection and autoimmunity; the role of infection in the expression of class II antigens; and processes responsible for the induction of autoimmune diseases. A specific therapy for these diseases is described. This monograph will be of interest to practitioners and researchers in immunology, experimental and clinical medicine, biochemistry, and other disciplines.", "author": "Michael Sela", "slug": "the-antigens-295345-9781483269665", "thumbnail_image": "//redshelf-images.s3-external-1.amazonaws.com/cover_image/9781483269665.jpg", "default_thumbnail_image": "//redshelf-images.s3-external-1.amazonaws.com/thumbnail/default_book_thumbnail.jpg", "product_type": "book", "product_id": "295345", "product_url": "/app/ecom/book/295345/the-antigens-295345-9781483269665", "bisac_codes": [ "SCI008000", "900" ], "items_count": null, "identifiers": { "ISBN13": "9780126355079", "EISBN13": "9781483269665", "EISBN10": "1483269663" }, "drm": null, "cover_image": null, "default_cover_image": null, "book_type": null }, "relationships": { "lowest_offering": { "data": { "type": "offerings", "id": "00010026369982" } } } }, { "type": "Product", "id": "00010000295346", "attributes": { "name": "Strategies of Immune Regulation", "subtitle": "", "description": "Strategies of Immune Regulation provides an overview of the state of knowledge on how immune regulation works. Many working scientists have taken the time to set down their views in one of two categories: (a) \"\"conventional\"\" short papers with standard documentation, (b) short expressions of opinion, with or without references. It is hoped that this book will act as a jumping-off point for new young workers, entering the field, who will ultimately fashion the next paradigm. The book contains 94 chapters organized into two sections. Section I begins with discussions of the general regulatory features of the immune systems. This is followed by papers on the role of the major histocompatibility complex and regulation involving the antibody molecules. The contributions in Section II cover the organization of Ig genes; antibody diversity and the development of the immune repertoire; MHC restriction; lymphocyte interactions and regulatory targets; role of the Ig receptor in triggering; function of IgD; lymphocyte maturation; idiotype regulation; and control of antiself reactions.", "author": "Eli Sercarz, Alastair J. Cunningham", "slug": "strategies-of-immune-regulation-295346-9781483270357", "thumbnail_image": "//redshelf-images.s3-external-1.amazonaws.com/thumbnail/9781483270357.jpg", "default_thumbnail_image": "//redshelf-images.s3-external-1.amazonaws.com/thumbnail/default_book_thumbnail.jpg", "product_type": "book", "product_id": "295346", "product_url": "/app/ecom/book/295346/strategies-of-immune-regulation-295346-9781483270357", "bisac_codes": [ "NAT019000", "SCI070030" ], "items_count": null, "identifiers": { "ISBN13": "9780126371406", "EISBN13": "9781483270357", "EISBN10": "1483270351" }, "drm": null, "cover_image": null, "default_cover_image": null, "book_type": null }, "relationships": { "lowest_offering": { "data": { "type": "offerings", "id": "00010026346753" } } } }, { "type": "Product", "id": "00010000295344", "attributes": { "name": "The Joints and Synovial Fluid", "subtitle": "Volume II", "description": "The Joints and Synovial Fluid II is a collection of papers that deals with the basic aspects of the articular apparatus, including the general pathology of the appendicular and axial structures, the disease processes, and comparative anthology. Some papers discuss in vitro culture of joints and articular tissues, the chemistry of the ground substance of joint cartilage, and the structure of the intervertebral disc in relation to its function and to the aging process. As a humans being ages, the whole nucleus found in the disc will behave more like a sponge than a shock absorber as regards its ability to distribute stress and pressure from the end plates of the disc. Another paper describes load distribution of the knee, ankle joint, the spine, the arms, elbows, fingers. One paper deals with the pathology of the spine covering infectious diseases, metabolic and developmental disease of cartilage and bones, traumatic and degenerative diseases, autoimmune connective tissue diseases (such as ankylosing spondylitis), and miscellaneous diseases (such as tumors). The collection is suitable for researchers, scientists, medical practitioners, and academicians in the fields of biochemistry, bioengineering, anatomical sciences, immunology, organ physiology, cell biology, orthopedics, rheumatology, or rehabilitation medicine.", "author": "Leon Sokoloff", "slug": "the-joints-and-synovial-fluid-295344-9781483259628", "thumbnail_image": "//redshelf-images.s3-external-1.amazonaws.com/cover_image/9781483259628.jpg", "default_thumbnail_image": "//redshelf-images.s3-external-1.amazonaws.com/thumbnail/default_book_thumbnail.jpg", "product_type": "book", "product_id": "295344", "product_url": "/app/ecom/book/295344/the-joints-and-synovial-fluid-295344-9781483259628", "bisac_codes": [ "MED075000", "SCI036000" ], "items_count": null, "identifiers": { "ISBN13": "9780126551020", "EISBN13": "9781483259628", "EISBN10": "1483259625" }, "drm": null, "cover_image": null, "default_cover_image": null, "book_type": null }, "relationships": { "lowest_offering": { "data": { "type": "offerings", "id": "00010026357116" } } } }, { "type": "Product", "id": "00010000295343", "attributes": { "name": "Early Experiences and Early Behavior", "subtitle": "Implications for Social Development", "description": "Early Experiences and Early Behavior: Implications for Social Development discusses the problems associated with determining the effects of early experiences on later behavior, with emphasis on social development, both in humans and in animals. The overall approach is one of constructive criticism, in that specific problems in methodology and conceptualization are highlighted and promising new approaches are suggested and illustrated. The book is divided into two parts. Part I deals with methodological, theoretical, and conceptual problems: Recurring problems of methodology and definition are specified; a thorough review of the animal literature in early experiences studies over the past quarter of a century pinpoints certain areas of progress among many other areas where advances have been sparse; and two newer approaches are discussed and supported, namely behavioral metamorphosis and the interactional-developmental approach. Part II presents two case studies which serve to exemplify a variety of older and newer approaches to the investigation of the effects of early experiences on social development.", "author": "Edward C. Simmel", "slug": "early-experiences-and-early-behavior-295343-9781483262918", "thumbnail_image": "//redshelf-images.s3-external-1.amazonaws.com/cover_image/9781483262918.jpg", "default_thumbnail_image": "//redshelf-images.s3-external-1.amazonaws.com/thumbnail/default_book_thumbnail.jpg", "product_type": "book", "product_id": "295343", "product_url": "/app/ecom/book/295343/early-experiences-and-early-behavior-295343-9781483262918", "bisac_codes": [ "SOC002000", "SOC053000" ], "items_count": null, "identifiers": { "ISBN13": "9780126440805", "EISBN13": "9781483262918", "EISBN10": "148326291X" }, "drm": null, "cover_image": null, "default_cover_image": null, "book_type": null }, "relationships": { "lowest_offering": { "data": { "type": "offerings", "id": "00010026358447" } } } }, { "type": "Product", "id": "00010000295342", "attributes": { "name": "Proceedings of the Conference on Finite Groups", "subtitle": "", "description": "Proceedings of the Conference on Finite Groups provides information pertinent to the fundamental aspects of finite group theory. This book presents the problem of characterizing simple groups in terms of the local structure of a group. Organized into five parts encompassing 43 chapters, this book begins with an overview of the characterization of the Chevalley groups over fields of odd order and indicates the role of this characterization in the theory of component type groups. This text then examines the structure as well as the representations of specific simple groups. Other chapters consider the general theory of representations and characters of finite groups. This book discusses as well permutation groups and the connection between group theory and geometry. The final chapter deals with finite solvable groups as well as the theory of formations. This book is a valuable resource for mathematicians, graduate students, and research workers.", "author": "William R. Scott, Fletcher Gross", "slug": "proceedings-of-the-conference-on-finite-groups-295342-9781483261089", "thumbnail_image": "//redshelf-images.s3-external-1.amazonaws.com/thumbnail/9781483261089.jpg", "default_thumbnail_image": "//redshelf-images.s3-external-1.amazonaws.com/thumbnail/default_book_thumbnail.jpg", "product_type": "book", "product_id": "295342", "product_url": "/app/ecom/book/295342/proceedings-of-the-conference-on-finite-groups-295342-9781483261089", "bisac_codes": [ "MAT002040", "500" ], "items_count": null, "identifiers": { "ISBN13": "9780126336504", "EISBN13": "9781483261089", "EISBN10": "1483261085" }, "drm": null, "cover_image": null, "default_cover_image": null, "book_type": null }, "relationships": { "lowest_offering": { "data": { "type": "offerings", "id": "00010026370049" } } } }, { "type": "Product", "id": "00010000295340", "attributes": { "name": "Metric Affine Geometry", "subtitle": "", "description": "Metric Affine Geometry focuses on linear algebra, which is the source for the axiom systems of all affine and projective geometries, both metric and nonmetric. This book is organized into three chapters. Chapter 1 discusses nonmetric affine geometry, while Chapter 2 reviews inner products of vector spaces. The metric affine geometry is treated in Chapter 3. This text specifically discusses the concrete model for affine space, dilations in terms of coordinates, parallelograms, and theorem of Desargues. The inner products in terms of coordinates and similarities of affine spaces are also elaborated. The prerequisites for this publication are a course in linear algebra and an elementary course in modern algebra that includes the concepts of group, normal subgroup, and quotient group. This monograph is suitable for students and aspiring geometry high school teachers.", "author": "Ernst Snapper, Robert J. Troyer", "slug": "metric-affine-geometry-295340-9781483269337-ernst-snapper-robert-j-troyer", "thumbnail_image": "//redshelf-images.s3-external-1.amazonaws.com/thumbnail/9781483269337.jpg", "default_thumbnail_image": "//redshelf-images.s3-external-1.amazonaws.com/thumbnail/default_book_thumbnail.jpg", "product_type": "book", "product_id": "295340", "product_url": "/app/ecom/book/295340/metric-affine-geometry-295340-9781483269337-ernst-snapper-robert-j-troyer", "bisac_codes": [ "MAT012000", "500" ], "items_count": null, "identifiers": { "ISBN13": "9780126536508", "EISBN13": "9781483269337", "EISBN10": "1483269337" }, "drm": null, "cover_image": null, "default_cover_image": null, "book_type": null }, "relationships": { "lowest_offering": { "data": { "type": "offerings", "id": "00010026350980" } } } }, { "type": "Product", "id": "00010000295341", "attributes": { "name": "Culture and Political Economy in Western Sicily", "subtitle": "", "description": "Culture and Political Economy in Western Sicily presents the relationship between the early colonial period, a time when Sicily exported wheat and animal products, and a later neocolonial period, during which manpower is the principal energy loss. The book discusses the rise and development of the Mafia; cultural codes that are important to contemporary social Sicilian organization; and the origins of these codes in early adaptations of the Sicilian people to externally generated political and economic forces. The text will be of value to sociologists, economists, historians, and people who want a deeper understanding of the Mafia.", "author": "Jane Schneider, Peter Schneider", "slug": "culture-and-political-economy-in-western-sicily-295341-9781483272689-jane-schneider-peter-schneider", "thumbnail_image": "//redshelf-images.s3-external-1.amazonaws.com/cover_image/9781483272689.jpg", "default_thumbnail_image": "//redshelf-images.s3-external-1.amazonaws.com/thumbnail/default_book_thumbnail.jpg", "product_type": "book", "product_id": "295341", "product_url": "/app/ecom/book/295341/culture-and-political-economy-in-western-sicily-295341-9781483272689-jane-schneider-peter-schneider", "bisac_codes": [ "SOC000000", "095" ], "items_count": null, "identifiers": { "ISBN13": "9780126278507", "EISBN13": "9781483272689", "EISBN10": "1483272680" }, "drm": null, "cover_image": null, "default_cover_image": null, "book_type": null }, "relationships": { "lowest_offering": { "data": { "type": "offerings", "id": "00010026352799" } } } }, { "type": "Product", "id": "00010000295339", "attributes": { "name": "Behavior of Nonhuman Primates", "subtitle": "Modern Research Trends", "description": "Behavior of Nonhuman Primates: Modern Research Trends, Volume 5 is a collection of papers on research trends in the study of the various aspects of primate behavior. Chapters in the book discuss topics on the history of the study of cognitive processes in primates; ways in which visual stimuli in monkeys are perceived, stored in memory, and retrieved; and behavior of prosimians. The book will be of value to primatologists, psychologists, and zoologists.", "author": "Allan M. Schrier, Fred Stollnitz", "slug": "behavior-of-nonhuman-primates-295339-9781483259604", "thumbnail_image": "//redshelf-images.s3-external-1.amazonaws.com/cover_image/9781483259604.jpg", "default_thumbnail_image": "//redshelf-images.s3-external-1.amazonaws.com/thumbnail/default_book_thumbnail.jpg", "product_type": "book", "product_id": "295339", "product_url": "/app/ecom/book/295339/behavior-of-nonhuman-primates-295339-9781483259604", "bisac_codes": [ "NAT019000", "SCI070030" ], "items_count": null, "identifiers": { "ISBN13": "9780126291056", "EISBN13": "9781483259604", "EISBN10": "1483259609" }, "drm": null, "cover_image": null, "default_cover_image": null, "book_type": null }, "relationships": { "lowest_offering": { "data": { "type": "offerings", "id": "00010026365393" } } } }, { "type": "Product", "id": "00010000295338", "attributes": { "name": "Elliptic Problem Solvers", "subtitle": "", "description": "Elliptic Problem Solvers provides information pertinent to some aspects of the numerical solution of elliptic partial differential equations. This book presents the advances in developing elliptic problem solvers and analyzes their performance. Organized into 40 chapters, this book begins with an overview of the approximate solution of using a standard Galerkin method employing piecewise linear triangular finite elements. This text then defines the types of vector architecture and discusses the variation in performance that can occur on a vector processor as a function of algorithm and implementation. Other chapters consider the implementation of techniques for elliptical problems. This book discusses as well the six techniques for the solution of nonsymmetric linear systems arising from finite difference discretization of the convection-diffusion equation. The final chapter deals with the basic semiconductor device equations. This book is a valuable resource for electrical and computer engineers, scientists, computer programmers, pure mathematicians, and research workers.", "author": "Martin H. Schultz", "slug": "elliptic-problem-solvers-295338-9781483259123", "thumbnail_image": "//redshelf-images.s3-external-1.amazonaws.com/thumbnail/9781483259123.jpg", "default_thumbnail_image": "//redshelf-images.s3-external-1.amazonaws.com/thumbnail/default_book_thumbnail.jpg", "product_type": "book", "product_id": "295338", "product_url": "/app/ecom/book/295338/elliptic-problem-solvers-295338-9781483259123", "bisac_codes": [ "MAT005000", "MAT034000" ], "items_count": null, "identifiers": { "ISBN13": "9780126326208", "EISBN13": "9781483259123", "EISBN10": "1483259129" }, "drm": null, "cover_image": null, "default_cover_image": null, "book_type": null }, "relationships": { "lowest_offering": { "data": { "type": "offerings", "id": "00010026356210" } } } }, { "type": "Product", "id": "00010000295337", "attributes": { "name": "The Antigens", "subtitle": "Volume III", "description": "The Antigens, Volume III is a comprehensive treatise covering all aspects of antigens, including their chemistry and biology as well as their immunologic role and expression. Topics covered range from microbial polysaccharides and lymphocytic receptors for antigens to antigenic determinants and antibody-combining sites. Allergens and the genetics of allergy are also explored. Comprised of seven chapters, this volume begins with a review of microbial polysaccharides as antigens, followed by a discussion on antigenic determinants and their specific reaction with antibody-combining sites. The reader is then introduced to the reaction of antigens with their specific receptors on lymphocytes. The next four chapters are concerned with several categories of more complex antigens which, in most cases, have yet to be characterized adequately at a molecular level: allergens, histocompatibility antigens, antigens of Mycoplasmatales and chlamydiae, and animal viruses. The book concludes with an analysis of virus infections and the immune responses they elicit. This monograph will be of interest to practitioners and researchers in immunology, experimental and clinical medicine, biochemistry, and other disciplines.", "author": "Michael Sela", "slug": "the-antigens-295337-9781483269566", "thumbnail_image": "//redshelf-images.s3-external-1.amazonaws.com/cover_image/9781483269566.jpg", "default_thumbnail_image": "//redshelf-images.s3-external-1.amazonaws.com/thumbnail/default_book_thumbnail.jpg", "product_type": "book", "product_id": "295337", "product_url": "/app/ecom/book/295337/the-antigens-295337-9781483269566", "bisac_codes": [ "HEA039000", "MED045000" ], "items_count": null, "identifiers": { "ISBN13": "9780126355031", "EISBN13": "9781483269566", "EISBN10": "1483269566" }, "drm": null, "cover_image": null, "default_cover_image": null, "book_type": null }, "relationships": { "lowest_offering": { "data": { "type": "offerings", "id": "00010026352561" } } } }, { "type": "Product", "id": "00010000295336", "attributes": { "name": "The Antigens", "subtitle": "Volume II", "description": "The Antigens, Volume II is a comprehensive treatise covering all aspects of antigens, including their chemistry and biology as well as their immunologic role and expression. Topics covered range from protein antigens and blood group antigens to low molecular weight antigens and immunoglobulin A. The idiotypy of antibodies is also explored, along with the application of antibodies to the measurement of substances of physiological and pharmacological interest. Comprised of six chapters, this volume begins with a discussion on the molecular bases of antigenicity and immunogenicity of proteins, followed by a chapter dealing with blood group antigens. The immunologic effects of low molecular weight antigens are then considered, together with their elicitation of allergic reactions and their tolerance and specific inhibition of the immune response. The next chapter focuses on the use of antibodies to measure substances of physiological and pharmacological interest, with emphasis on the general principle of quantitative immunoassay. The book also analyzes the idiotypy of antibodies before concluding with a description of the antibody functions of immunoglobulin A. This monograph will be of interest to practitioners and researchers in immunology, experimental and clinical medicine, biochemistry, and other disciplines.", "author": "Michael Sela", "slug": "the-antigens-295336-9781483269559", "thumbnail_image": "//redshelf-images.s3-external-1.amazonaws.com/cover_image/9781483269559.jpg", "default_thumbnail_image": "//redshelf-images.s3-external-1.amazonaws.com/thumbnail/default_book_thumbnail.jpg", "product_type": "book", "product_id": "295336", "product_url": "/app/ecom/book/295336/the-antigens-295336-9781483269559", "bisac_codes": [ "SCI013030", "900" ], "items_count": null, "identifiers": { "ISBN13": "9780126355024", "EISBN13": "9781483269559", "EISBN10": "1483269558" }, "drm": null, "cover_image": null, "default_cover_image": null, "book_type": null }, "relationships": { "lowest_offering": { "data": { "type": "offerings", "id": "00010026362106" } } } }, { "type": "Product", "id": "00010000295335", "attributes": { "name": "Handbook of VLSI Chip Design and Expert Systems", "subtitle": "", "description": "Handbook of VLSI Chip Design and Expert Systems provides information pertinent to the fundamental aspects of expert systems, which provides a knowledge-based approach to problem solving. This book discusses the use of expert systems in every possible subtask of VLSI chip design as well as in the interrelations between the subtasks. Organized into nine chapters, this book begins with an overview of design automation, which can be identified as Computer-Aided Design of Circuits and Systems (CADCAS). This text then presents the progress in artificial intelligence, with emphasis on expert systems. Other chapters consider the impact of design automation, which exploits the basic capabilities of computers to perform complex calculations and to handle huge amounts of data with a high speed and accuracy. This book discusses as well the characterization of microprocessors. The final chapter deals with interactive I/O devices. This book is a valuable resource for system design experts, circuit analysts and designers, logic designers, device engineers, technologists, and application-specific designers.", "author": "A. F. Schwarz", "slug": "handbook-of-vlsi-chip-design-and-expert-systems-295335-9781483258058-a-f-schwarz", "thumbnail_image": "//redshelf-images.s3-external-1.amazonaws.com/cover_image/9781483258058.jpg", "default_thumbnail_image": "//redshelf-images.s3-external-1.amazonaws.com/thumbnail/default_book_thumbnail.jpg", "product_type": "book", "product_id": "295335", "product_url": "/app/ecom/book/295335/handbook-of-vlsi-chip-design-and-expert-systems-295335-9781483258058-a-f-schwarz", "bisac_codes": [ "TEC009070", "077" ], "items_count": null, "identifiers": { "ISBN13": "9780126324259", "EISBN13": "9781483258058", "EISBN10": "148325805X" }, "drm": null, "cover_image": null, "default_cover_image": null, "book_type": null }, "relationships": { "lowest_offering": { "data": { "type": "offerings", "id": "00010026353544" } } } }, { "type": "Product", "id": "00010000295334", "attributes": { "name": "The Evolution of Protein Structure and Function", "subtitle": "A Symposium in Honor of Professor Emil L. Smith", "description": "The Evolution of Protein Structure and Function documents the proceedings of the symposium \"\"Evolution of Protein Structure and Function\"\" held at the Dickson Art Auditorium, University of California Los Angeles (UCLA), 28-29 June 1979. Its objective was to honor Professor Emil L. Smith on the occasion of his retirement as Professor and Chairman, Department of Biological Chemistry, School of Medicine, UCLA. The papers presented by Emils colleagues, friends, and students from all phases of his long and varied scientific career provided a valuable review of enzymology, protein chemistry, and biochemical evolution. The volume contains 16 chapters is organized into three parts. Part I contains papers on enyzmology, including the role of the recA protein of Escherichia coli in general recombination; the evolution of enzyme families; and studies on metalloenzymes. Part II takes up protein structure and function. It includes papers on glycoprotein hormones, thymus hormones, chromosome biology and chemistry, and the evolution of histones. Part III examines the evolution of proteins, including the evolution of cythochrome c and evolution of phycobilisome of cyanobacteria and red algae.", "author": "David S. Sigman, Mary A. B. Brazier", "slug": "the-evolution-of-protein-structure-and-function-295334-9781483262819", "thumbnail_image": "//redshelf-images.s3-external-1.amazonaws.com/cover_image/9781483262819.jpg", "default_thumbnail_image": "//redshelf-images.s3-external-1.amazonaws.com/thumbnail/default_book_thumbnail.jpg", "product_type": "book", "product_id": "295334", "product_url": "/app/ecom/book/295334/the-evolution-of-protein-structure-and-function-295334-9781483262819", "bisac_codes": [ "SCI008000", "907" ], "items_count": null, "identifiers": { "ISBN13": "9780126431506", "EISBN13": "9781483262819", "EISBN10": "1483262812" }, "drm": null, "cover_image": null, "default_cover_image": null, "book_type": null }, "relationships": { "lowest_offering": { "data": { "type": "offerings", "id": "00010026357101" } } } }, { "type": "Product", "id": "00010000295333", "attributes": { "name": "Bleomycin Chemotherapy", "subtitle": "", "description": "Bleomycin Chemotherapy focuses on the clinical uses of bleomycin. Bleomycin, a group of glycopeptides isolated from Streptomyces verticillus, has a unique structure and mechanism of action among anticancer drugs. The drugs remarkable lack of bone marrow toxicity prompted its addition to myelosuppressive regimens and enabled treatment of patients with compromised hematopoietic function. Bleomycin is an integral component of one of the great triumphs of medical oncologythe curative treatment of metastatic testicular carcinomas. Similar curative potential has been demonstrated for bleomycin in combination with cisplatin and vinblastine in germ-cell cancers of the ovary. Bleomycin is included in several important treatment regimens for Hodgkin's disease and non-Hodgkin's lymphomas. The drug also has clinical activity against squamous carcinomas of various sites. These uses and other aspects, including the development of new bleomycin analogs, are discussed in the following chapters, which were first presented at a symposium jointly sponsored by the Northern California Cancer Program and Bristol Laboratories in San Francisco, California, 14-15 September 1984.", "author": "Branimir Ivan Sikic, Marcel Rozencweig, Stephen K. 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